PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Link between signaling molecules could point way to therapies for epilepsy, stroke, other diseases

2011-01-08
(Press-News.org) SAN ANTONIO (Jan. 7, 2010) — In the Old West, camps sent smoke signals across distances to share key developments or strategy. Likewise, two important signaling molecules communicate across nerve cells to regulate electrical and chemical activity, neuroscientists from the UT Health Science Center San Antonio reported today.

The findings in rodent models have implications for potential future treatment of epilepsy, stroke and other problems, the researchers said.

"We now have novel targets for therapeutic intervention for a range of neurological and cardiovascular diseases, including stroke, epilepsy, dementia, hypertension, mental illness and others," said senior author Mark S. Shapiro, Ph.D., professor of physiology at the Health Science Center. "This study should guide clinicians and pharmaceutical companies in developing new therapies against mental, neurological, cardiovascular or cerebrovascular diseases that afflict many millions of people."

By isolating nerve cells from rats, the San Antonio team found a relationship between signaling enzymes called phosphoinositide kinases and calcium ions. Calcium transport and levels of calcium concentrations inside nerve cells are extremely important for proper neurobiological function, Dr. Shapiro said.

In epilepsy, for example, it is thought that the hyper-excitability in the brain causes abnormal elevations of intracellular calcium ions, which is extremely toxic. Thus, epileptic seizures often predispose people to additional seizures, as the normal regulation of brain activity increasingly breaks down.

The study is in the Jan. 7 issue of the Journal of Biological Chemistry.

INFORMATION: On Twitter and the Web

For current news from the UT Health Science Center San Antonio, please visit our news release website or follow us on Twitter @uthscsa.

About the UT Health Science Center San Antonio

The University of Texas Health Science Center at San Antonio, one of the country's leading health sciences universities, ranks in the top 3 percent of all institutions worldwide receiving National Institutes of Health (NIH) funding. Research and other sponsored program activity totaled a record $259 million in fiscal year 2009. The university's schools of medicine, nursing, dentistry, health professions and graduate biomedical sciences have produced approximately 26,000 graduates. The $744 million operating budget supports eight campuses in San Antonio, Laredo, Harlingen and Edinburg. For more information on the many ways "We make lives better®," visit www.uthscsa.edu.


ELSE PRESS RELEASES FROM THIS DATE:

Prof. Erantha De Mel Receives The US President's Service Award

2011-01-08
Sri-Lankan born Psychologist / Cognitive Neuroscientist Prof. Erantha De Mel received the President's Call to Service Award at a ceremony held in Washington DC recently. This distinguished service award by President Barack Obama was presented to him for his outstanding services to the American community in the fields of Psychology and Psychotherapy. This lifetime achievement award was established in 2003 after President George W. Bush created the President's Council on Service and Civic Participation. It is given annually to individuals who have dedicated over 4,000 ...

GridBuddy: an award-winning cloud application for the Force.com platform

2011-01-08
Salesforce.com announced that AppBuddy's new application GridBuddy was recognized as one of the top 4 installed applications in the 'Hack into Dreamforce' contest. Awards were given to applications with the highest number of customer AppExchange software installs between 9/20/10 and 11/30/10 leading up to the annual Dreamforce conference. GridBuddy is a 100% native Force.com application that allows users to edit multiple related Salesforce objects using an Excel-like view. GridBuddy has a clean, simple-to-use interface for users to view one parent object with multiple ...

Start Your New Year With A Kick, Women Self-Defense Lessons

2011-01-08
In recent years, programs geared to women only have began to take popularity. From fitness kickboxing classes, boot camps, and women fitness clubs -- women only programs have taken off like a grand slam in baseball. Starting on February 7th, 2011, local martial arts and fitness school owner and instructor, Javier Lozano, Jr. will be teaching a series of 8 Week Women Self-Defense Courses throughout the year. These 8 week courses are designed to teach women the basic fundamentals of empty-hand self-defense by using effective strikes, kicks, and blocks to fend ...

Newly Announced Webinar Compares Agile Software Development from Nearshore and Farshore Viewpoints

2011-01-08
The benefits and risks of IT outsourcing to Latin America will be explored in-depth during a special one-hour webinar coming January 25th at 2 p.m. EST. "The Agile Alternative: What Does Mexico Have that India Doesn't?", hosted by the premiere IT offshoring blog - Nearshore Americas, examines the value proposition of relying on 'nearshore' partners to provide custom application development services. Register today by visiting: http://www.csvep.com/registration/view.php?id=123 Geared toward IT decision makers and managers responsible for software development, testing ...

FoodEnquirer.com - Celebrate The Oat Meal Month And Lower Your Cholesterol

2011-01-08
To start with, it is important that we clear things up. The oatmeal that will give you health benefits are those made from pure oak flakes. The instant oatmeals will do you more harm than good since they have much sugar in them; not to mention traces of preservatives. Having oatmeal for breakfast is a good way to pump you full of energy and start the day. Aside from giving you the boost you need, there are tons of benefits of eating oatmeal. This is why it became a favorite household food item. The first of the obvious benefits of eating oatmeal is it contains fiber, ...

Real World Leader's Institute Co-Founders Debora Mclaughlin And Donna Price, Launch Their Radio Show: Real World Leadership At Blogtalkradio.

2011-01-08
With today's economy and the unique needs of today's work force the face of leadership is changing. Authority driven leadership no longer works and current employee engagement statistics report that only 29% of today's workforce are engaged, reporting to work focused on meeting performance and business outcomes. Successful companies are focusing on educating leaders on employee engagement and current cutting edge leadership strategies to positively affect the bottom line. January 5th, 2011 Debora McLaughlin, CEO of Open Door Coaching and co-founder of The Real World ...

Wall Street Journal: Scoring Unlisted Jobs (80% of job openings are unlisted)

2011-01-08
Job boards are irresistible because they seemingly put everything within easy reach. Unfortunately, the majority of job hunters are competing for the same small pool of jobs and getting turned down. More than 80% of job openings are actually unlisted, says Steven Rothberg, founder of job website CollegeRecruiter.com in Minneapolis. This can be a good opportunity for outside candidates with research and networking skills since most companies will try to promote from within or rely on employee referrals. Look for signs: Keep up with what's going on in your industry. ...

Barnes & Noble is 'Hound Bound' with Brimstone and the Borderhounds

2011-01-08
Hound Comics is proud to formally announce that its flagship brand, "Brimstone and The Borderhounds" will officially be on the shelves of Barnes & Noble and Book World retail stores nationwide on Tuesday, January 11th! On this date, the brand new comic book will be available in bookstores as well as online worldwide via Amazon.com. Hot off the official launch signing held at Borders Books & Music (October 2010 - Westbury, NY) this past fall, the "Hounds" are excited their fans will have full access to their latest endeavor. "Brimstone and the Borderhounds" is a comic ...

K-12 Digital Menu Boards with Nutritional Labeling - Simple and Effective way to fight Obesity

2011-01-08
Epicure Digital, a leader in digital menu boards, presents the Epicure Digital Menu System with special emphasis on nutritional labeling at the California School Nutrition Association (CSNA) Annual Conference and Exhibition in Pasadena, California, January 14-15, 2011, Booth #415. Epicure Digital Systems is a digital menu board company uniquely integrating its expertise in software technology and food service operations and marketing to create digital signage products and services for the food service industry. Its core product is the Epicure Digital Menu System . Its ...

Brite Future Continues Expansion with New Branch in North Miami Beach

2011-01-08
Brite Future Plumbing, Inc., a leading provider of residential and commercial plumbing services in the South Florida area, recently established its newest branch in North Miami Beach, Florida. The new North Miami Beach Plumbers branch will act as a strategic center for sales and support services to the Dade County market. "The Brite Future North Miami Beach team consists of some of the most talented plumbing experts familiar with all areas of residential and commercial plumbing," said Cassandra Cordero, President of Brite Future Plumbing. "We are committed to meeting ...

LAST 30 PRESS RELEASES:

Study unexpectedly finds living in rural, rather than urban environments in first five years of life could be a risk factor for developing type 1 diabetes

Editorial urges deeper focus on heart-lung interactions in pulmonary vascular disease

Five University of Tennessee faculty receive Fulbright Awards

5 advances to protect water sources, availability

OU Scholar awarded Fulbright for Soviet cinema research

Brain might become target of new type 1 diabetes treatments

‘Shore Wars:’ New research aims to resolve coastal conflict between oysters and mangroves, aiding restoration efforts

Why do symptoms linger in some people after an infection? A conversation on post-acute infection syndromes

Study reveals hidden drivers of asthma flare-ups in children

Physicists decode mysterious membrane behavior

New insights about brain receptor may pave way for next-gen mental health drugs

Melanoma ‘sat-nav’ discovery could help curb metastasis

When immune commanders misfire: new insights into rheumatoid arthritis inflammation

SFU researchers develop a new tool that brings blender-like lighting control to any photograph

Pups in tow, Yellowstone-area wolves trek long distances to stay near prey

AI breakthrough unlocks 'new' materials to replace lithium-ion batteries

Making molecules make sense: A regional explanation method reveals structure–property relationships

Partisan hostility, not just policy, drives U.S. protests

The Journal of Nuclear Medicine Ahead-of-Print Tip Sheet: August 1, 2025

Young human blood serum factors show potential to rejuvenate skin through bone marrow

Large language models reshape the future of task planning

Narrower coverage of MS drugs tied to higher relapse risk

Researchers harness AI-powered protein design to enhance T-cell based immunotherapies

Smartphone engagement during school hours among US youths

Online reviews of health care facilities

MS may begin far earlier than previously thought

New AI tool learns to read medical images with far less data

Announcing XPRIZE Healthspan as Tier 5 Sponsor of ARDD 2025

Announcing Immortal Dragons as Tier 4 Sponsor of ARDD 2025

Reporting guideline for chatbot health advice studies

[Press-News.org] Link between signaling molecules could point way to therapies for epilepsy, stroke, other diseases