PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Physical activity and incident obesity across the spectrum of genetic risk for obesity

JAMA Network Open

2024-03-27
(Press-News.org) About The Study: Individuals at high genetic risk of obesity needed higher daily step counts to reduce the risk of obesity than those at moderate or low genetic risk in this study of 3,124 adults. Population-based recommendations may underestimate physical activity needed to prevent obesity among those at high genetic risk. 

Authors: Evan L. Brittain, M.D., M.Sc., and Douglas M. Ruderfer, Ph.D., of the Vanderbilt University Medical Center in Nashville, are the corresponding authors.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ 

 (doi:10.1001/jamanetworkopen.2024.3821)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.3821?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=032724

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

END


ELSE PRESS RELEASES FROM THIS DATE:

Researchers create new tool for assessing risk of kidney injury after chemotherapy

2024-03-27
Using patient data from six major U.S. cancer centers, Brigham researchers and collaborators developed a risk prediction model for moderate-to-severe kidney injury after receiving the chemotherapy drug cisplatin in the largest, first generalizable study of its kind Cisplatin is a highly effective chemotherapy that has been used to treat cancer for decades, but it can cause kidney injury that can potentially lead to the discontinuation of life-saving cancer treatments. Investigators from Brigham and Women’s Hospital (BWH), a founding member of the Mass General Brigham healthcare system, with researchers from the Dana-Farber Cancer Institute and other institutions, ...

Estimated sustainable cost-based prices for diabetes medicines

2024-03-27
About The Study: High prices limit access to newer diabetes medicines in many countries. The findings of this study suggest that robust generic and biosimilar competition could reduce prices to more affordable levels and enable expansion of diabetes treatment globally.  Authors: Melissa J. Barber, Ph.D., of the Yale Collaboration for Regulatory Rigor, Integrity, and Transparency in New Haven, Connecticut, is the corresponding author.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamanetworkopen.2024.3474) Editor’s ...

Higher genetic risk of obesity means working out harder for same results

Higher genetic risk of obesity means working out harder for same results
2024-03-27
Persons with a higher genetic risk of obesity need to work out harder than those of moderate or low genetic risk to avoid becoming obese, according to a Vanderbilt University Medical Center (VUMC) paper published in JAMA Network Open.   Study authors used activity, clinical and genetic data from the National Institutes of Health’s All of Us Research Program to explore the association of genetic risk of higher body mass index and the level of physical activity needed to reduce incident obesity.   “Physical activity guidelines do not ...

The ISSCR announces 2024 election results

The ISSCR announces 2024 election results
2024-03-27
Evanston, IL – The International Society for Stem Cell Research (ISSCR) is pleased to announce the results of its 2024 election. Lorenz Studer, MD, founding director of the Center for Stem Cell Biology and member of the Developmental Biology Program, Memorial Sloan Kettering Cancer Center, USA, will become the next Vice President. All terms of office for the new leaders will begin on 1 July 2024. The following three members were newly elected to the ISSCR Board of Directors for a three-year term: Jacqueline Barry, PhD, ...

Safer, more efficient drug discovery

2024-03-27
McGill researchers have discovered a safer and more efficient technique for testing new drugs while they are in development. “Because this approach is so much more streamlined, it could help accelerate this step in the drug development process and make it less dangerous, since probing the distribution and fate of a drug in the body is required for any pharmaceutical candidate to be approved,” says Bruce A. Arndtsen, a James McGill Professor who teaches in the Department of Chemistry at McGill and is the senior author on the paper describing the new process, published recently in Nature Chemistry. “This research replaces what can be a days’ long, dangerous and ...

New image of the center of our Milky Way: Spiral magnetic fields surround black hole Sagittarius A*

New image of the center of our Milky Way: Spiral magnetic fields surround black hole Sagittarius A*
2024-03-27
FRANKFURT. In 2022, scientists of the EHT unveiled the first image of Sgr A* – which is approximately 27,000 light-years away from Earth – revealing that the Milky Way’s supermassive black hole looks remarkably similar to M87’s, even though it is more than a thousand times smaller and less massive.  This made scientists wonder whether the two shared common traits outside of their looks. To find out, the team decided to study Sgr A* in polarized light. Previous studies of light around M87* had shown that the magnetic fields around the gigantic black hole allowed it to launch powerful jets of material back into the surrounding environment. ...

A promising discovery in a rare neurodegenerative disease

2024-03-27
Imagine being middle aged and starting to feel that you are off balance a lot and that you are having a hard time coordinating your movements. Those are among the symptoms of Spinocerebellar ataxia type 6, known as SCA6, a rare neurodegenerative disease which typically appears in adulthood and worsens over time. Over time, other problems such as slurred speech and difficulty seeing or seeing double, may also appear. It is estimated that fewer than 5,000 people in the US have the condition, which is the result of genetic mutations in the cerebellum. The disease currently has no cure. But this may change, thanks to a new discovery made by McGill researchers. In ...

Extreme heat and ozone pollution: A call for targeted control strategies in China

Extreme heat and ozone pollution: A call for targeted control strategies in China
2024-03-27
Elevated surface ozone concentrations in China are posing a significant threat to both human health and crop yields. Extreme heat can greatly exacerbate ozone pollution through both complex chemical and physical processes. For example, extreme heat is often accompanied by stagnant weather conditions, which can lead to the accumulation and subsequent elevation of ozone. Considering that extreme heat events have been becoming increasingly frequent in recent decades, and are also expected to do so on into the future, effective control strategies to reduce ozone pollution risks are urgently needed. Therefore, a research group led by Prof. Ke ...

Researchers discover a mechanism that could improve platinum-based cancer therapy

2024-03-27
AURORA, Colo. (March 27, 2024) – Researchers have identified a protein that, when targeted, enables cisplatin-resistant cancer cells to become responsive to treatment. Cisplatin, and other similar platinum drugs, are incredibly effective at killing rapidly growing cancer cells, which is why they have been used in treating cancers for over 45 years. However, these drugs are non-targeted and can cause debilitating toxic side effects, resulting in a diminished lifestyle, and patients in poor health are deemed ineligible for use. In a study, published today in Cancer Research, a journal of the American Association for Cancer Research, researchers say they ...

Memory self-test via smartphone can identify early signs of Alzheimer’s disease

2024-03-27
Dedicated memory tests on smartphones enable the detection of “mild cognitive impairment”, a condition that may indicate Alzheimer’s disease, with high accuracy. Researchers from DZNE, the Otto-von-Guericke University Magdeburg and the University of Wisconsin-Madison in the United States who collaborated with the Magdeburg-based company “neotiv” report these findings in the scientific journal npj Digital Medicine. Their study is based on data from 199 older adults. The results underline the potential of mobile apps for Alzheimer’s disease research, clinical trials and routine medical care. The app that ...

LAST 30 PRESS RELEASES:

Global Virus Network statement on Nipah virus outbreak

A new molecular atlas of tau enables precision diagnostics and drug targeting across neurodegenerative diseases

Trends in US live births by race and ethnicity, 2016-2024

Sex and all-cause mortality in the US, 1999 to 2019

Nasal vaccine combats bird flu infection in rodents

Sepsis study IDs simple ways to save lives in Africa

“Go Red. Shop with Heart.” to save women’s lives and support heart health this February

Korea University College of Medicine successfully concludes the 2025 Lee Jong-Wook Fellowship on Infectious Disease Specialists Program

Girls are happiest at school – for good reasons

Researchers from the University of Maryland School of Medicine discover genetic ancestry is a critical component of assessing head and neck cancerous tumors

Can desert sand be used to build houses and roads?

New species of ladybird beetle discovered on Kyushu University campus

Study identifies alternate path for inflammation that could improve RA treatment

MANA scientists enable near-frictionless motion of pico- to nanoliter droplets with liquid-repellent particle coating

Chung-Ang University scientists generate electricity using Tesla turbine-inspired structure

Overcoming the solubility crisis: a solvent-free method to enhance drug bioavailability

Baby dinosaurs a common prey for Late Jurassic predators

Land-intensive carbon removal requires better siting to protect biodiversity

Devastation of island land snails, especially in the Pacific

Microwaves help turn sugar industry waste into high-performance biochar

From craft dust to green gold: Turning palm handicraft waste into high value bio based chemicals

New roadmap shows how to turn farm nitrogen models into real world water quality gains

Heart damage is common after an operation and often goes unnoticed, but patients who see a cardiologist may be less likely to die or suffer heart disease as a result

New tool exposes scale of fake research flooding cancer science

Researchers identify new blood markers that may detect early pancreatic cancer

Scientists uncover why some brain cells resist Alzheimer's disease

The Lancet: AI-supported mammography screening results in fewer aggressive and advanced breast cancers, finds full results from first randomized controlled trial

New AI tool improves treatment of cancer patients after heart attack

Kandahar University highlights global disparities in neurosurgical workforce and access to care

Research spotlight: Discovering risk factors for long-term relapse in alcohol use disorder

[Press-News.org] Physical activity and incident obesity across the spectrum of genetic risk for obesity
JAMA Network Open