BMI and postacute sequelae of SARS-CoV-2 infection in children and young adults

JAMA Network Open

2024-10-28

(Press-News.org) About The Study: In this cohort study, elevated body mass index (BMI) was associated with a significantly increased post-acute sequelae of SARS-CoV-2 infection risk in a dose-dependent manner, highlighting the need for targeted care to prevent chronic conditions in at-risk children and young adults.

Corresponding Author: To contact the corresponding author, Yong Chen, PhD, email ychen123@pennmedicine.upenn.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2024.41970)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2024.41970?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=102824

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

Cannabis use during pregnancy can impact thinking and learning skills, increase aggression among children, study shows

2024-10-28

(COLUMBUS, Ohio) – As cannabis is legalized and is more accessible in various forms across the country, there is increasing concern among health care providers about potential impact on children. Researchers at Nationwide Children’s Hospital have new findings to add to the existing evidence that cannabis exposure before birth can negatively impact children. In a study published today in JAMA Pediatrics, researchers found prenatal cannabis exposure was associated in early childhood with poorer thinking skills and behaviors such as impulse control, paying attention, planning ability, and more aggressive behavior, all of ...

Children’s Hospital of Philadelphia researchers discover underlying mechanisms that make CRISPR an effective gene editing tool

2024-10-28

Philadelphia, October 28, 2024 – CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy. However, until now, the precise mechanism of exactly how this tool works and avoids creating detrimental off-target effects was not well understood. Now, using state-of-the-art technology, researchers from Children’s Hospital of Philadelphia (CHOP) have identified several specific steps needed for CRISPR to become active and perform its gene editing function. These preclinical findings could lead to improved designs for CRISPR-based ...

Age-period-cohort analysis of cutaneous malignant melanoma incidence in the United States from 1987 to 2016

2024-10-28

Background and objectives The prevalence and fatality rates of cutaneous malignant melanoma (CMM) have been rising, particularly among the elderly. This study analyzes CMM incidence trends in the United States elderly population from 1987 to 2016 to inform prevention and management strategies. Methods Using incidence data from the Surveillance, Epidemiology, and End Results database spanning 1989 to 2008, we calculated the age-adjusted standardized population incidence rates for CMM in elderly individuals. The Joinpoint ...

NCCN Cancer Center study demonstrates usability of Health Equity Report Card (HERC) tool for driving fair access to care

2024-10-28

MINNEAPOLIS, MN [October 28, 2024] — Today, the National Comprehensive Cancer Network® (NCCN®) is presenting preliminary data from a study evaluating the usability of the Health Equity Report Card (HERC) tool during the American Public Health Association (APHA) Annual Meeting and Expo. The HERC was created by the Elevating Cancer Equity collaboration between NCCN, the American Cancer Society Cancer Action Network (ACS CAN), and the National Minority Quality Forum (NMQF) and updated by a subsequent working group. It features 19 practice evaluation and change recommendations designed to help providers and healthcare organizations identify and address disparity and bias in care ...

SwRI adds new chamber for spacecraft-related EMC, EMI testing

2024-10-28

SAN ANTONIO — October 28, 2024 —Southwest Research Institute (SwRI) has added a semi-anechoic shielded enclosure for electromagnetic compatibility and interference (EMC/EMI) testing for spacecraft. The test chamber is the next step in SwRI’s plans to create a turnkey spacecraft integration and test center within its 74,000-square-foot Space System Spacecraft and Payload Processing Facility. The 400-square-foot EMC/EMI Chamber is semi-anechoic, or free of echo, and shielded from electromagnetic interference. It supports performance of standard emissions and susceptibility testing with an upper frequency limit of 40 gigahertz ...

Molecular profiling using next-generation sequencing of sufficient endobronchial ultrasound-guided transbronchial needle aspiration and liquid biopsy samples in patients with advanced lung cancer

2024-10-28

Background and objectives Tumor molecular analysis using next-generation sequencing (NGS) is the standard of care for guiding lung cancer treatment. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive technique used to sample mediastinal lymph nodes for diagnosing and staging lung cancer. This study aimed to determine if EBUS-TBNA provided adequate tissue samples for NGS. Methods We evaluated EBUS-TBNA samples from adult advanced non-small cell lung cancer patients who had both ...

Case Western Reserve University awarded $2.6 million to study impact of high blood-pressure medications on chronic kidney disease patients

2024-10-28

CLEVELAND—The National Institutes of Health awarded a four-year, $2.6 million grant to researchers at Case Western Reserve University to study how high blood-pressure drugs affect patients with chronic kidney disease (CKD). More specifically, they want to study whether such medications increase the risk of kidney and cardiovascular disease in CKD patients. More than one in seven Americans suffer from CKD, according to the U.S. Centers for Disease Control and Prevention (CDC). CKD is a condition where ...

Dramatic drop in marijuana use among U.S. youth over a decade: (2011 to 2021)

2024-10-28

Marijuana has emerged as one of the most commonly used illicit substances among adolescents in the United States. Given the rising number of states legalizing recreational marijuana for adults and the decreasing perception of risk among adolescents, tracking trends in youth marijuana use is more crucial than ever. Researchers from Florida Atlantic University’s Schmidt College of Medicine conducted a comprehensive study using data from the Youth Risk Behavior Survey between 2011 and 2021, which surveyed 88,183 adolescents in grades nine through 12. Researchers focused on the overall time trends in use of marijuana ...

Exploring unlabeled data for enhanced semi-supervised MRI segmentation

2024-10-28

Researchers from Peking University Third Hospital have developed a novel collaborative framework that integrates various semi-supervised learning techniques to enhance MRI segmentation using unlabeled data. This new approach, published in Health Data Science, leverages advanced deep learning models to significantly improve segmentation accuracy, even when labeled data is scarce. MRI segmentation plays a crucial role in medical imaging, aiding in the precise partitioning of MR images into different regions or structures. While deep learning-based ...

Inhaled reliever therapies for asthma

2024-10-28

About The Study: In this network meta-analysis of patients with asthma, inhaled corticosteroids combined with formoterol and inhaled corticosteroids combined with short-acting β agonists were each associated with reduced asthma exacerbations and improved asthma control compared with short-acting β agonists alone. Corresponding Author: To contact the corresponding author, Derek K. Chu, MD, PhD, email chudk@mcmaster.ca. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jama.2024.22700) Editor’s ...

The Lancet: Deeply entrenched racial and geographic health disparities in the USA have increased over the last two decades—as life expectancy gap widens to 20 years

Mass General Brigham and BIDMC researchers unveil an AI protein engineer capable of making proteins ‘better, faster, stronger’

Metabolic and bariatric surgery safe and effective for patients with severe obesity

Smarter city planning: MSU researchers use brain activity to predict visits to urban areas

Using the world’s fastest exascale computer, ACM Gordon Bell Prize-winning team presents record-breaking algorithm to advance understanding of chemistry and biology

BMI and postacute sequelae of SARS-CoV-2 infection in children and young adults

ELSE PRESS RELEASES FROM THIS DATE:

LAST 30 PRESS RELEASES: