(Press-News.org) Barcelona, Spain - 12 June 2025 - The EBMT, the EHA, and the GoCART Coalition proudly announce the release of the second edition of the EU CAR-T Handbook, a comprehensive, open-access resource covering the latest developments in CAR-T cell therapies. This updated edition provides expanded insights into scientific advances, clinical applications, and evolving regulatory frameworks.
Developed with contributions from leading experts in academia and industry, the new edition includes approximately 50% more chapters than the first and offers broader coverage of clinical management, including emerging indications such as autoimmune diseases. It also introduces content on other immune cellular therapies such as tumour-infiltrating lymphocytes, extending the handbook’s relevance to solid tumours.
Given the rapid evolution of the field—marked by new products, indications, and advances in related therapies such as bispecific antibodies—this edition reflects significant shifts in clinical decision-making and redefines treatment algorithms. It incorporates international perspectives, further enhancing its value as a global reference for healthcare professionals.
Professor Christian Chabannon, Editor-in-Chief, stated: “The EU CAR-T Handbook is a key component of our educational efforts and will serve as the foundational material for the upcoming CAR-T Passport—a practical resource for clinicians, nurses, pharmacist and other healthcare professionals involved in CAR-T and other Immune Effector Cell (IECs) therapies.”
The second edition was first presented at the 51st Annual Meeting of the EBMT in April 2025 in Florence, Italy, and subsequently at the EHA Annual Congress in June 2025. It is freely available online, underscoring the EBMT, EHA, and GoCART Coalition’s commitment to accessible education and knowledge-sharing in cellular therapies.
Access the handbook here: https://www.ebmt.org/education/carthandbook/#/
About EBMT:
The EBMT is a non-profit medical and scientific organisation established in 1974 which hosts a unique patient registry providing a pool of data to perform studies and assess new trends. We aim to be the connection between patients, researchers and other stakeholders to anticipate the future of cellular and stem cell-based therapies. Our community of healthcare professionals is focused on innovation, research and the advancement of these fields to save and improve the lives of patients with blood-related disorders.
For more information, please visit www.ebmt.org.
Follow @TheEBMT on X, LinkedIn, Facebook and YouTube
About EHA:
The European Hematology Association (EHA) is a membership association that promotes excellence in patient care, research, and education in hematology. EHA works towards its mission by connecting hematologists worldwide, supporting their career development and research, through harmonizing education and advocating the interests of hematology. EHA brings together relevant stakeholders so that, together, we can shape the future of hematology.
For more information, please visit www.ehaweb.org.
Follow @EHA on X, LinkedIn, Facebook, Instagram and YouTube
About GoCART Coalition:
GoCART is a multi-stakeholder coalition in the field of gene and cellular therapies manufactured from cells and tissues of haematopoietic origin. The Coalition was launched in 2020 and brings together stakeholders from across the sector, including health care professionals, patients, health authorities, Health Technology Assessment bodies and reimbursement agencies, pharmaceutical companies and medical non-profit organisations. The Coalition was founded by EHA and EBMT, the two leading European societies in the field of haematology and stem cell transplantation.
For more information, please visit https://thegocartcoalition.com.
Follow @TheGoCoaltion on X and LinkedIn
Press Contacts:
EBMT: Mélanie Chaboissier, Communication Coordinator, Email: melanie.chaboissier@ebmt.org
EHA: Georgie Mills, Marketing & PR Coordinator, Email: g.mills@ehaweb.org
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About The Study: In adult patients receiving mechanical ventilation and supplemental oxygen in the intensive care unit, minimizing oxygen exposure through conservative oxygen therapy did not significantly reduce all-cause mortality at 90 days.
Corresponding Author: To contact the corresponding author, Daniel S. Martin, PhD, email daniel.martin@plymouth.ac.uk.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
(doi:10.1001/jama.2025.9663)
Editor’s Note: Please see the article for additional information, including other authors, ...
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