PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Japanese P2 study shows potential of combined vaccine and steroid drug in castration resistant PCa

2013-03-15
(Press-News.org) Arnhem, 11 March 2013- Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer (CRPC) patients.

The study, which won the third prize for best abstract in oncology at the 28th European Association of Urology Congress held in Milan, Italy from 15 to 19 March, showed the promising benefit of this combination therapy in patients who are chemotherapy-naive or those not yet exposed to specific antigens.

"Results of our randomized prospective study suggest that multi-peptide vaccination therapy in combination with low dose dexamethasone has the therapeutic potential as a safe and efficient option for chemotherapy-naïve CRPC patients," said lead study author Dr. Takahiro Kimura, of the Jikei University School of Medicine, Dept. of Urology, Tokyo, Japan.

Since immunotherapy does not have a strong ability to decrease tumour burden, it is considerably difficult to evaluate the full extent of a significant therapeutic effect with peptide vaccines, explained Kimura. "Taking this into consideration, the present evidence is promising," he said.

The researchers have previously developed MHC class-I restricted peptide vaccines for prostate cancer and carried out a phase 1 trial to assess safety and immunological evaluation. In the present study, Kimura and his colleagues conducted a randomized phase 2 study to evaluate the efficacy of peptide vaccine therapy for chemotherapy naïve CRPC patients.

Early stage CRPC (PSA END


ELSE PRESS RELEASES FROM THIS DATE:

Study shows additional role for abiraterone in blocking tumor growth in CRPC

2013-03-15
Arnhem, 14 March 2013 - As part of an EU-supported IMI-PREDECT consortium (http://www.predect.eu), a Dutch study showed that anti-androgenic properties of the drug abiraterone may provide an additional mechanism of action in blocking tumour growth of castration resistant prostate cancer (CRPC). The study, which won the first prize for best abstract in oncology at the 28th European Association of Urology (EAU) Congress to be held in Milan from March 15 to 19, demonstrated that although the use of abiraterone can potentially lead to an accumulation of precursor hormones, ...

Many Americans have more credit card debt than savings, survey says

2013-03-15
Many Americans have more credit card debt than savings, survey says Article provided by Jeffrey P. White and Associates, P.C. Visit us at http://www.whitelawoffices.com Financial experts often recommend that you keep almost three month's pay on hand in case it is needed in an emergency. This is sound advice, but nonetheless advice that many Americans are not heeding, according to a recent survey by Bankrate.com. For the survey, Bankrate.com asked participants what they have more of: credit card debt or emergency savings. The results were quite frightening. Only ...

SSA expands Compassionate Allowances list

2013-03-15
SSA expands Compassionate Allowances list Article provided by Alan J. Nuta, Attorney at Law Visit us at http://www.ssbenefitslawyer.com If you have ever filed for disability benefits, you know that the process is often long and arduous. In order to qualify for benefits in most cases, the Social Security Administration (SSA) requires you to prove that you have a disabling condition that prevents you from working for at least a year (or result in your death). As this can be difficult to prove, many initial applications are denied, requiring the applicant to file and ...

Agency says new commercial bus seat belt requirement is coming soon

2013-03-15
Agency says new commercial bus seat belt requirement is coming soon Article provided by Greenstein & Milbauer, LLP Visit us at http://www.nyclawfirm.com/ After years of debate, regulations that will require all new commercial buses to have safety belts installed are likely to come "very soon," said David Strickland, National Highway Traffic Safety Administrator, at the North American International Auto Show. The use of seat belts on buses is a key factor in reducing the risk of serious injury in an accident, and some bus companies are already buying ...

Grandparent visitation rights in Pennsylvania

2013-03-15
Grandparent visitation rights in Pennsylvania Article provided by Prince Law Offices, P.C. Visit us at http://www.princelaw.com During a separation and subsequent divorce, grandparents may find that they do not get to see their grandkids as often. In a tragic event when an adult child dies, grandparents might also have fewer opportunities to see their grandchildren. Pennsylvania law has strict criteria for grandparents seeking more time with their grandchildren. Because of the requirements, it is a good idea to consult a grandparents' rights attorney when relationships ...

What happens when parents cannot come to a child custody agreement?

2013-03-15
What happens when parents cannot come to a child custody agreement? Article provided by Law Offices of Jonathan W. Fein Visit us at http://www.feinlaw.com When a couple decides that they can no longer make their marriage or relationship work, they begin taking the necessary steps toward ending their relationship. This can be an extremely emotional time, leaving both parties to wonder what went wrong. When a couple has children, they will need to determine a child custody arrangement that will meet the needs of both parents, as well as the child. This can become ...

How is child custody handled in Colorado?

2013-03-15
How is child custody handled in Colorado? Article provided by Frost & Beck, LLP Visit us at http://www.frostbecklaw.com When a married couple with children decides to divorce, typically the most pressing and difficult questions involve how decision-making responsibilities and the children's time will be divided. In Colorado, the courts consider a number of factors before making these decisions. Physical custody is referred to as "parenting time" in Colorado. Parents are also responsible for making decisions on behalf of their children regarding ...

NHTSA to ask automakers to crank up the volume on hybrids

2013-03-15
NHTSA to ask automakers to crank up the volume on hybrids Article provided by Law Offices of Aleixo and Murray, P.C. Visit us at http://www.aleixoandmurray.com Whether it is because of the rising cost of gas or the desire to leave a smaller carbon footprint, hybrid vehicles have exploded in popularity in recent years. Although the vehicles deliver on their promise to be "greener" than gas or diesel engines, they come with a dark side: they operate at such a low volume at slow speeds that bicyclists and pedestrians often cannot hear them, putting them at ...

Beware of asset concealment when divorcing a small-business owner

2013-03-15
Beware of asset concealment when divorcing a small-business owner Article provided by The Law Firm of Hauer & Snover Visit us at http://www.hauersnover.com/ In Michigan, the law provides that divorcing couples must divide their property according to the principle of equitable distribution. This means that their property must be divided equitably, or fairly, but not necessarily equally. The rule of equitable distribution applies to a couple's marital property, which typically includes all assets acquired by either spouse during the marriage, such as bank accounts, ...

Widespread consequences likely in Massachusetts drug lab scandal

2013-03-15
Widespread consequences likely in Massachusetts drug lab scandal Article provided by Carleen & Caramanica, P.C. Visit us at http://www.massfelonydefense.com A chemist formerly employed by a Massachusetts drug lab was accused in September 2012 of tampering with tens of thousands of drug samples over a period of nine years, allegedly falsifying the results used in a multitude of criminal cases. 34,000 criminal cases may have been affected Massachusetts Gov. Deval Patrick has ordered a "file-by-file" review of every case handled by the chemist over ...

LAST 30 PRESS RELEASES:

UMass Amherst Nursing Professor Emerita honored as ‘Living Legend’

New guidelines aim to improve cystic fibrosis screening

Picky eaters by day, buffet by night: Butterfly, moth diets sync to plant aromas

Pennington Biomedical’s Dr. Leanne Redman honored with the E. V. McCollum Award from the American Society for Nutrition

CCNY physicists uncover electronic interactions mediated via spin waves

Researchers’ 3D-printing formula may transform future of foam

Nurture more important than nature for robotic hand

Drug-delivering aptamers target leukemia stem cells for one-two knockout punch

New study finds that over 95% of sponsored influencer posts on Twitter were not disclosed

New sea grant report helps great lakes fish farmers navigate aquaculture regulations

Strain “trick” improves perovskite solar cells’ efficiency

How GPS helps older drivers stay on the roads

Estrogen and progesterone stimulate the body to make opioids

Dancing with the cells – how acoustically levitating a diamond led to a breakthrough in biotech automation

Machine learning helps construct an evolutionary timeline of bacteria

Cellular regulator of mRNA vaccine revealed... offering new therapeutic options

Animal behavioral diversity at risk in the face of declining biodiversity

Finding their way: GPS ignites independence in older adult drivers

Antibiotic resistance among key bacterial species plateaus over time

‘Some insects are declining but what’s happening to the other 99%?’

Powerful new software platform could reshape biomedical research by making data analysis more accessible

Revealing capillaries and cells in living organs with ultrasound

American College of Physicians awards $260,000 in grants to address equity challenges in obesity care

Researchers from MARE ULisboa discover that the European catfish, an invasive species in Portugal, has a prolonged breeding season, enhancing its invasive potential

Rakesh K. Jain, PhD, FAACR, honored with the 2025 AACR Award for Lifetime Achievement in Cancer Research

Solar cells made of moon dust could power future space exploration

Deporting immigrants may further shrink the health care workforce

Border region emergency medical services in migrant emergency care

Resident physician intentions regarding unionization

Healthy nutrition and physical lifestyle choices lower cancer mortality risk for survivors, new ACS study finds

[Press-News.org] Japanese P2 study shows potential of combined vaccine and steroid drug in castration resistant PCa