How to make ageing a ‘fairer game’ for all wormkind
Why do some people live for longer than others? The genes in our DNA sequence are important, helping avoid disease or maintain general health, but differences in our genome sequence alone explain less than 30% of the natural variance of human life expectancy. Exploring how ageing is influenced at the molecular level could shed light on lifespan variation, but generating data at the speed, scale and quality necessary to study this in humans is unfeasible. Instead, researchers turn to worms (Caenorhabditis elegans). Humans share a lot of biology with these small creatures, who also have a large, natural variation in lifespan. Researchers ...
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