Immune cells play an active and intimate role in directing the growth of human lung tissue during development, researchers find, revolutionising our understanding of early lung development and the role of immune cells outside of immunity. The research offers new insights for understanding and treating respiratory conditions, such as chronic obstructive pulmonary disease (COPD). Respiratory conditions account for almost 20 per cent of all deaths in children under five years worldwide1. The work reveals a surprising coordination between the immune and respiratory systems, much earlier in development than previously thought. This discovery raises questions about the ...

New research has revealed that Rembrandt impregnated the canvas for his famous 1642 militia painting ‘The Night Watch’ with a lead-containing substance even before applying the first ground layer. Such lead-based impregnation has never before been observed with Rembrandt or his contemporaries. The discovery, published today in Science Advances, underlines Rembrandt's inventive way of working,  in which he did not shy away from using new techniques. The surprising observation is yet another result from Operation Night Watch, the largest and most wide-ranging research and conservation project in the history ...

Salmon researchers from British Columbia are embarking on a three-year study to understand and help mitigate the cumulative threats affecting the vulnerable species in the province’s watersheds. The Watershed Futures Initiative, which includes researchers from Simon Fraser University, University of British Columbia and University of Montana, has received $1.25 million from the federal and provincial governments – through the joint British Columbia Salmon Restoration and Innovation Fund – to tackle the combined impacts of logging, mining, urban development, agriculture, climate change and other factors on salmon.   While ...

The average menstruator will use over 11,000 tampons or sanitary pads in their lifetime. Vaginal and vulvar tissue that touch pads and tampons is highly permeable. Through this permeable tissue chemicals are absorbed without being metabolized, which makes endocrine-disrupting chemicals potentially dangerous when found in menstrual products. Endocrine-disrupting chemicals can interfere with human hormones and cause medical issues, including gynecological conditions such as endometriosis and uterine fibroids.  Joanna Marroquin, a Mason PhD in Public Health student, and Associate ...

The U.S. Department of Energy’s (DOE) Argonne National Laboratory has named five highly accomplished scientists as Argonne Distinguished Fellows in 2023. They are Glenn Decker, Paul Fenter, Robert Fischetti, Sven Leyffer and Valentine Novosad. The honor recognizes scientists who have not only achieved international esteem but who have also demonstrated exceptional achievements in science or engineering relevant to Argonne’s core missions. They are leaders of major, complex, high-priority projects or programs that have an impact on the future of the Laboratory. Only a small ...

Exposure to phthalates, a group of plasticizing and solvent chemicals found in many household products, was linked to a lower probability of getting pregnant, but not to pregnancy loss, according to research by a University of Massachusetts Amherst environmental and reproductive epidemiologist. The study, published this week in the journal Environmental Health Perspectives, also noted an association between preconception exposure to phthalates and changes in women’s reproductive hormones, as well as increased inflammation and oxidative stress.   “Phthalates ...

WASHINGTON  –  Debra Rolison, Ph.D., of the U.S. Naval Research Laboratory (NRL) has been named Fellow of the National Academy of Inventors (NAI), for having demonstrated a highly prolific spirit of innovation in creating and facilitating outstanding inventions that have made a tangible impact on the quality of life, economic development, and welfare of society.   Rolison has been at the lab for over 43 years and heads the Advanced Electrochemical Materials section. The recognition by the NAI is attributed to the efforts made by her team’s inventions related to a new form factor for zinc anodes in rechargeable ...

SAN FRANCISCO — One of the hottest debates in archeology is how and when humans first arrived in North America. Archaeologists have traditionally argued that people walked through an ice-free corridor that briefly opened between ice sheets an estimated 13,000 years ago.   But a growing number of archeological and genetic finds — including human footprints in New Mexico dated to around 23,000 years old — suggests that people made their way onto the continent much earlier. These early Americans likely traveled along the Pacific coastline from Beringia, the land bridge between Asia and North America ...

We are pleased to announce that the American Institute of Aeronautics and Astronautics (AIAA), a preeminent aerospace professional society, has selected professor Xinfeng Gao to be a member of the class of 2024 AIAA associate fellows. Only one member of the Institute for every 150 members is selected as an associate fellow each year by the review committee. “This recognition illustrates the impact of our outstanding faculty. Aerospace engineering at UVA continues on a great trajectory and professor Gao is a big part of that,” said Richard W. Kent, professor and chair of the Department of Mechanical and Aerospace Engineering. Pioneering ...

Addiction is one of society’s most misunderstood and rebuked health conditions. That stigma discourages many people from seeking treatment for substance dependence, according to a new report published in Psychological Science in the Public Interest, a journal of the Association for Psychological Science.  Research on stigma toward people with substance use disorder (SUD) is relatively sparse, the report adds. “Characterizing the nature and etiology of SUD stigma is critical for developing tailored and effective interventions ...

LAWRENCE — Research appearing in ACS Nano, a premier journal on nanoscience and nanotechnology, reveals the ballistic movement of electrons in graphene in real time. The observations, made at the University of Kansas’ Ultrafast Laser Lab, could lead to breakthroughs in governing electrons in semiconductors, fundamental components in most information and energy technology. “Generally, electron movement is interrupted by collisions with other particles in solids,” said lead author Ryan Scott, ...

In southern China, the genetically improved slash pine (Pinus elliottii) plays a crucial role in timber and resin production, with new shoot density being a key growth trait. Current manual counting methods are inefficient and inaccurate. Emerging technologies such as UAV-based RGB imaging and deep learning (DL) offer promising solutions. However, DL methods face challenges in global feature capture, necessitating additional mechanisms. Innovations like the Vision Transformer and its derivatives (e.g., TransCrowd, CCTrans) show potential in plant trait counting, offering simplified and more effective approaches for large-scale and accurate ...

BALTIMORE, December 14, 2023– In a landmark study led by the University of Maryland School of Medicine, researchers discovered for the first time that a certain kind of protein similar to hemoglobin, called cytoglobin, plays an important role in the development of the heart. Specifically, it affects the correct left-right pattern of the heart and other asymmetric organs. The findings, published today in the journal Nature Communications, could eventually lead to the development of new therapeutic interventions to alter the processes that lead ...

EMBARGOED FOR RELEASE UNTIL FRIDAY DECEMBER 15 AT 11 A.M. EST. U.S. hospitals charge facility fees for colonoscopy procedures covered by private health insurance that are on average approximately 55 percent higher than facility fees billed by smaller clinics known as ambulatory surgical centers, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.  The findings appear in a peer-reviewed research letter to be published online December 15 in JAMA Health Forum. Colonoscopies ...

About The Study: The results of this study of data on 57,000 adults who received living donor kidney transplants indicate that additional work is necessary to identify transplant program and center-level strategies to improve racial equity in access to living donor kidney transplant.  Authors: Lisa M. McElroy, M.D., M.S., of the Duke University School of Medicine in Durham, North Carolina, is the corresponding author.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamanetworkopen.2023.47826) Editor’s Note: Please see the article for additional information, ...

About The Study: In this study of 18,000 academic physicians, approximately one-third reported moderate or greater intention to leave within two years. Burnout, lack of professional fulfillment, and other well-being factors were associated with intention to leave, suggesting the need for a comprehensive approach to reduce physician turnover.  Authors: Mickey T. Trockel, M.D., Ph.D., of the Stanford University School of Medicine in Stanford, California, is the corresponding author.  To access the embargoed study: Visit ...

About The Study: Fewer calories were purchased in restaurants with calorie labels compared with those with no labels, suggesting that consumers are sensitive to calorie information on menu boards, according to the results of this study of 2,329 Mexican-inspired fast food restaurants in six U.S. locations. Associations differed by location.  Authors: Brian Elbel, Ph.D., M.P.H., of the New York University School of Medicine in New York, is the corresponding author.  To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/  (doi:10.1001/jamanetworkopen.2023.46851) Editor’s ...

About The Study: The findings of this diagnostic study of 1,890 eyes of 958 participants support the potential of artificial intelligence as an objective tool in screening for autism spectrum disorder (ASD) and possibly for symptom severity using retinal photographs. Retinal photograph use may speed the ASD screening process, which may help improve accessibility to specialized child psychiatry assessments currently strained by limited resources.  Authors: Yu Rang Park, Ph.D., and Keun-Ah Cheon, M.D., Ph.D., ...

Positive tipping points must be triggered if we are to avoid the severe consequences of damaging Earth system tipping points, researchers say. With global warming on course to breach 1.5oC, at least five Earth system tipping points are likely to be triggered – and more could follow. Once triggered, Earth system tipping points would have profound local and global impacts, including sea-level rise from major ice sheet melting, mass species extinction from dieback of the Amazon rainforest and disruption to weather patterns from a collapse of large-scale ocean circulation currents. The new commentary – published in One Earth by researchers from the Global Systems Institute at ...

A paper published today in JAMA Network Open addresses bias in healthcare algorithms and provides the healthcare community with guiding principles to avoid repeating errors that have tainted the use of algorithms in other sectors. This work, conducted by a technical expert panel co-chaired by Marshall Chin, MD, MPH, the Richard Parrillo Family Distinguished Service Professor of Healthcare Ethics at the University of Chicago, supports the Biden Administration Executive Order 14091, Further Advancing Racial Equity and Support for Underserved Communities Through The Federal Government, issued on February 16, 2023. President Biden calls for Federal ...

In a rapid communication published in the journal Genes & Diseases, researchers from Chongqing Medical University and Yongchuan Traditional Chinese Medicine Hospital of Chongqing have unveiled crucial insights into the factors that might influence Intervertebral Disc Degeneration (IDD). IDD is a predominant cause of lower back pain, impacting millions worldwide. The focus of this research revolved around nucleus pulposus cells (NPCs), pivotal in IDD, and how oxygen levels and the HIF1A gene could influence them. ...

In a rapid communication published in the journal Genes & Diseases, has shed light on the role of the Wnt signaling pathway in influencing the immune response of colorectal cancer (CRC) patients. Researchers from Nankai University discovered that abnormalities in this pathway can affect a patient's response to immunotherapy, paving the way for more tailored treatment strategies. They integrated transcriptome data from 425 CRC patients, aiming to explore the underlying mechanism of MSI. They identified that the Wnt signaling pathway, essential for various cellular processes, showed signs of inhibition in MSI patients. The team also noted a significant down-regulation in mismatch repair ...

Patients struggling with some chronic diseases often must wait years for a proper diagnosis. For example, symptoms such as shortness of breath can be attributed to many pulmonary as well as cardiovascular disorders, so patients may be treated for a misdiagnosed disease that is far from accurate diagnosis and treatment. Therefore, one of the most promising methods to deal with this problem is to track the levels of specific compounds in the body during the development of a specific disease. Moving in this direction, scientists at the Institute of Physical Chemistry of the Polish Academy of Sciences (Warsaw, Poland) and the National ...

“Antimicrobial resistance is a major problem, and being able to help solve it is really great,” says Amanda Holstad Singleton, a PhD candidate at the Norwegian University of Science and Technology (NTNU). Singleton is the lead author of a study that shows how a combination of two new substances effectively kills methicillin-resistant Staphylococcus aureus (MRSA). These substances have been developed at NTNU and may become a completely new antibiotic that is effective against a wide group of bacteria. “It's ...

Frontiers for Young Minds, the award-winning, open-access scientific journal for kids, has published the first articles in a new collection in collaboration with CERN, one of the world’s largest centers for scientific research. The collection, entitled SPARK-ing big questions: what is the future of health technology?, addresses key questions on how ground-breaking health technologies and science can improve human health for future generations.   The articles are written by researchers who attended the SPARKS! Serendipity Forum at CERN in 2022, an event for scientific and ...