New research has found that adolescents with higher levels of an omega-3 fatty acid in their blood were less likely to develop psychotic disorder in early adulthood, suggesting that it may have a potential preventative effect of reducing the risk of psychosis. The study, led by researchers from RCSI University of Medicine and Health Sciences, is published in END ...

The routine use of the glycosylated hemoglobin test to track blood sugar levels in the general population can identify individuals with more advanced atherosclerotic disease. Currently used in the diagnosis and management of diabetes, glycosylated hemoglobin can provide a useful estimate of atherosclerotic disease, and therefore of cardiovascular risk, in individuals without diabetes with or without possible prediabetes. This is the main finding of a study carried out by scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC). The advance heralded by the CNIC study is the use of this blood-sugar measure in apparently healthy middle-aged ...

Skoltech researchers used the resources of the university's Zhores supercomputer to study a new method of generating gamma-ray combs for nuclear and X-ray photonics and spectroscopy of new materials. The paper was published in the journal Physical Review Letters. A gamma-ray comb is a series of short bursts that, when plotted as intensity versus frequency, look like sharp and equally spaced teeth of a comb. Generating these combs at high brightness in the gamma-ray domain has been challenging because of something called ponderomotive spectral broadening - an effect that destroys the monochromaticity that allows gamma-ray sources to be used in nuclear spectroscopy, medicine, and other applications. Sergey ...

The intriguing chemistry and biology of sulfur?containing natural products from marine microorganisms (1987-2020) https://doi.org/10.1007/s42995-021-00101-2 Announcing a new publication for Marine Life Science & Technology journal. In this review article the authors Yang Hai, Mei?Yan Wei, Chang?Yun Wang, Yu?Cheng Gu and Chang?Lun Shao from Ocean University of China, Qingdao, China and Syngenta Jealott's Hill International Research Centre, Berkshire, UK consider the chemistry and biology of sulfur?containing natural products from marine microorganisms. Natural products derived ...

The National Institute of Polar Research (NIPR) publishes Polar Science, a peer-reviewed quarterly journal dealing with polar science in collaboration with the Elsevier B. V.. The most recent issue (Vol. 27 published in March 2021) was a special issue entitled "Arctic Challenge for Sustainability Project (ArCS)," which featured the former national (nation-wide) Arctic research project in Japan. The full text of this issue is freely accessible worldwide for a limited time until 10 September 2021. The Arctic Research Project "Arctic Challenge for Sustainability (ArCS)" was carried out from September 2015 to March 2020 as a national flagship project funded by the Ministry of Education, Culture, Sports, ...

In past studies, researchers have found that C. elegans gonads generate more germ cells than needed and that only half of them grow to become oocytes, while the rest shrinks and die by physiological apoptosis, a programmed cell death that occurs in multicellular organisms. Now, scientists from the Biotechnology Center of the TU Dresden (BIOTEC), the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), the Cluster of Excellence Physics of Life (PoL) at the TU Dresden, the Max Planck Institute for the Physics of Complex Systems (MPI-PKS), the Flatiron Institute, NY, and the University of California, Berkeley, found evidence to answer the question of what triggers this cell fate decision between life and death in the germline. Prior studies ...

Researchers from Trinity College Dublin have developed a novel set of tools for designing vitamin D clinical trials that capture large seasonal and population-wide differences in vitamin D status, typically seen in individuals. Their study published in the journal Scientific Reports (today, Monday 31st May 2021) provides a framework for clinical trials to establish whether vitamin D supplementation is effective against a given disease. The study also reveals that many trials which failed to find any association between vitamin D and disease prevention may have been underpowered or conducted without enough subjects to detect a benefit of vitamin D. You can read the full journal paper here: https://go.nature.com/3uERjgO The ...

YouTube is a treasure trove of virtual reality fails: users tripping, colliding into walls and smacking inanimate and animate objects. By investigating these "VR Fails" on YouTube, researchers at the University of Copenhagen have sought to learn more about when and why things go sideways for users and how to improve VR design and experiences so as to avoid accidents. Millions of YouTube viewers have enjoyed hearty laughs watching others getting hurt using virtual reality - people wearing VR headsets, falling, screaming, crashing into walls and TV sets, or knocking spectators to the floor. Some of us have even been that failing someone. Now, videos of virtual reality mishaps, called "VR Fails", ...

Redox-flow batteries store electrical energy in chemical compounds that are dissolved in an electrolyte. They are a particularly promising alternative to lithium-ion batteries as stationary energy storage. A team headed by Prof. Dr. Ingo Krossing from the Institute of Inorganic and Analytical Chemistry at the University of Freiburg has succeeded in developing a non-aqueous All-Manganese Flow battery (All-MFB) that uses sustainable manganese as its active material and has a long cycle life. The researchers present the results of their work in the latest edition of Advanced Energy Materials. Active materials are ...

Energy communities will play a key role in building the more decentralised, less carbon intensive, and fairer energy systems of the future. Such communities enable local prosumers (consumers with own generation and storage) to generate, store and trade energy with each other -- using locally owned assets, such as wind turbines, rooftop solar panels and batteries. In turn, this enables the community to use more locally generated renewable generation, and shifts the market power from large utility companies to individual prosumers. Energy community projects often involve jointly-owned assets such as community-owned wind turbines or shared battery storage. Yet, this raises the question of how these assets should be controlled - often in real time, and how the energy outputs jointly-owned ...

Thyroid nodules are a common pathology having a prevalence of 19-76% when screened with ultrasound, with higher frequencies in women. Current medical methods used to assess the malignancy of a nodule consist in performing an ultrasound, followed by a Doppler ultrasound, and then a biopsy. However, unfortunately, these methods present both low specificity and low sensitivity. This insufficient effectiveness in accurately being able to diagnose thyroid tumors leads to many unclear or unnoticed cases as well as many others that undergo unnecessary surgeries (false positives) and increase the cost ...

When the Augustinian monk Gregor Mendel crossed white-flowering with purple-flowering pea plants in the mid-19th century, he made an interesting discovery: The offspring were all purple. He therefore called this trait dominant, while the white blossom color was recessive. The reason for this phenomenon: In peas, each gene occurs twice. One version comes from the maternal plant and the other from the paternal plant. If a pea has inherited the gene for purple flower color from one parent, but the gene for white flower color from the other, purple wins. Only when two genes for white flowers come together in the offspring plant is it white. Humans also have genes that are inherited either dominantly or recessively. However, the case is not so clear for the mutations investigated ...

Using a Fitbit and a spy mic, scientists have discovered new insight into the behaviour of the elusive Canada lynx. A new study by researchers from McGill University, University of Alberta, and Trent University provides a first look at how miniaturized technology can open the door to remote wildlife monitoring. "Working on one of the boreal forest's top predators, the Canada lynx, we found that two different technologies, accelerometers and audio recording devices, can be used to remotely monitor the hunting behaviour of predators, even documenting the killing of small prey," says lead author Emily Studd, a Postdoctoral Fellow under the supervision of Murray Humphries at McGill University and Stan Boutin at University ...

The University of Ottawa's Positive Energy program released new survey results showing that a large segment of the Canadian public does not trust the courts to settle disputes over energy projects or climate policy. The survey was conducted by Positive Energy's official pollster, Nanos Research. Canadians were asked: On a scale of 0 to 10, where 0 means do not trust at all and 10 means trust completely, how much do you trust the courts to settle disputes over government decisions on energy projects? They were asked the same question for climate policy. The results are very similar. Only one in three Canadians trust the courts to settle disputes over energy projects or climate policy (answering between 7 and 10: 31% for energy, 30% for ...

Machine learning, when used in climate science builds an actual understanding of the climate system, according to a study published in the journal Chaos by Manuel Santos Gutiérrez and Valerio Lucarini, University of Reading, UK, Mickäel Chekroun, the Weizmann Institute, Israel and Michael Ghil, Ecole Normale Supérieure, Paris, France. This means we can trust machine learning and further its applications in climate science, say the authors. The study is part of the European Horizon 2020 TiPES project on tipping points in the Earth system. TiPES is administered from the University of Copenhagen, Denmark. Man or ...

Humans are exposed to a bath of chemicals every day. They are in the beds where we sleep, the cars that we drive and the kitchens we use to feed our families. With thousands of chemicals floating around in our environment, exposure to any number is practically unavoidable. Through the work of researchers like Dr. Deborah Kurrasch, PhD, the implications of many of these chemicals are being thoroughly explored. "Manufacturers follow standards set by regulatory bodies, it's not up to the manufacturers to prove the chemicals in consumer products are safe," says Kurrasch, a researcher in the University of Calgary's Hotchkiss Brain ...

Right-wing voices set out powerful but misleading arguments to justify inaction by the Trump administration during the COVID-19 pandemic, according to a new study of the rhetoric used by high-level government officials and influential commentators in the US during the first half of 2020. In a study published in the DeGruyter journal Open Anthropological Research, Professor Martha Lincoln of San Francisco State University examined how public officials openly pushed for people to accept widespread illness and death from the virus by adopting a tone that suggested premature death was normal and the scale of death acceptable in the grander ...

RUDN mathematician and his colleagues from China, Egypt, Saudi Arabia, United Kingdom, and Qatar have developed an algorithm allowing the distribution of computing tasks between the IoT devices and the cloud in an optimal way. As a result, the power and time costs are reduced by about three times. The study was published in the Big Data. With the development of technologies and devices, Internet of Things (IoT) applications require more and more computing power. The amount of data that the IoT devices need to process can be so large that it is reasonable to migrate computing to the cloud. Cloud computing provides flexible data processing and storage capabilities. But Computation offloading, meaning transferring of the resource-intensive processes ...

A DTU research team consisting of Malgorzata Gosia Pierchala, Firoz Babu Kadumundi, and Mehdi Mehrali from #TeamBioEngine headed by Alireza Dolatshahi-Pirouz, have developed a new material - CareGum - that among other things has potential for monitoring motor impairment associated with neurological disorders such as Parkinson's. A green material with many properties The CareGum property portfolio is incredibly broad with feats such as skin-like softness, it is stretchable up to 30,000 % and has self-healing capacities reminiscent of that of natural tissues. It is printable, moldable, and electrically conductive. Notably, the electrical conductivity enables the material to respond to external stimuli ...

Oncotarget published "STAT3 induces the expression of GLI1 in chronic lymphocytic leukemia cells" which reported that what induces GLI1 expression in GLI1-unmutated CLL cells is unknown. Because signal transducer and activator of transcription 3 is constitutively activated in CLL cells and sequence analysis detected putative STAT3-binding sites in the GLI1 gene promoter, the authors hypothesized that STAT3 induces the expression of GLI1. Western immunoblotting detected GLI1 in CLL cells from 7 of 7 patients, flow cytometry analysis confirmed that CD19 /CD5 CLL cells co-express GLI1 and confocal microscopy showed co-localization of GLI1 and phosphorylated STAT3. Chromatin immunoprecipitation showed ...

A series of autopsies performed in an infectious disease hospital in the Brazilian Amazon reveals that infections by the Histoplasma fungus are a major cause of death in people with HIV. The study, led by Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation, in collaboration with a team in Manaus, highlights the need of implementing sensitive methods to detect these infections in Histoplasma-endemic regions. Histoplasmosis is a lung infection caused by inhalation of spores from a fungus (Histoplasma), and is frequent in some areas of the US, Africa, and Latin America. In the majority of individuals with a functional immune system, the infection causes mild symptoms. However, in people who are immuno-compromised, such ...

Scientists at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) in Japan have developed a technology that produces high-resolution simulations of one of the basic units of our genomes, called the nucleosome. Their findings were published in the journal Nature Protocols and should help improve understanding of how changes in nucleosome folding influence the inner workings of genes. Nucleosomes are the basic structural units of DNA packaging inside the nucleus. They are formed of DNA wrapped around a small number of histone proteins. Nucleosomes move around inside the nucleus, folding and unfolding, changing their orientations, and moving closer together or further apart. These movements affect the accessibility of various molecules to DNA, determining ...

A new discovery in Ewing sarcoma, an aggressive and often fatal childhood cancer, has uncovered the potential to prevent cancer cells from spreading beyond their primary tumour site. The breakthrough provides new insight into what triggers the process that allows cancer cells to survive while traveling through the body in the bloodstream. Researchers with the University of British Columbia and BC Cancer have learned that Ewing sarcoma cells--and likely other types of cancer cells--are able to develop a shield that protects them from the harsh environment of the bloodstream and other locations as they search for a new place to settle, or metastasize. The study has just been published in Cancer Discovery. "You ...

TROY, N.Y. -- As more dissolved organic matter enters lakes across the northeast United States, darkening the lakes in a phenomena called "browning," new research shows that these waters may be growing less productive and able to sustain less life. In a study published today in Limnology and Oceanography Letters, scientists found that, rather than enriching lakes with nutrients as had previously been assumed, water more heavily laden with dissolved organic matter blocks sunlight and limits plant growth. "A key question regarding lake browning is what impact it will have on aquatic food webs, including algal growth and fisheries," said Kevin Rose, co-author ...

The brain is often likened to a computer: its hardware - neurons organized in complex circuits, its software - a plethora of codes that govern the neurons' behavior. But sometimes the brain performs exceptionally well even when its hardware seems inadequate for the task. For example, it's been puzzling how we and other mammals manage to navigate large-scale environments even though the brain's spatial perception circuits are seemingly suited to representing much smaller areas. A team of researchers from the Weizmann Institute of Science, led by Prof. Nachum Ulanovsky of the Neurobiology Department, tackled this riddle by thinking outside the experimental box. By combining an unusual research model - fruit bats - with an unusual setting - a 200 meters-long bat-tunnel - they were ...