Alzheimer Europe sets out recommendations to improve data sharing in dementia research
2021-02-23
Luxembourg, 23 February 2021 - At an online European Parliament workshop hosted by Deirdre Clune MEP (Ireland), Alzheimer Europe launched a new report "Data Sharing in Dementia Research", which reviews recent changes in EU research policy and sets out recommendations to improve data sharing in dementia research.
In this report, Alzheimer Europe evaluates the legal and policy landscapes that dementia researchers have had to navigate since the launch of Horizon 2020 in 2013. The report identifies key barriers and enablers for data sharing. It maps the Horizon 2020 dementia research portfolio, assessing the scale of EU investment in dementia research and the use of clinical ...
Saki monkeys get screen time for more control over their lives in captivity
2021-02-23
Helsinki, Finland--Technology helps humans maintain connections, get work done, and relax after a long day. How it can best improve the lives of animals, particularly those in captivity, however, has remained an open question.
Scientists from Aalto University, in collaboration with Korkeasaari Zoo, have designed and built an on-demand video device for white-faced saki monkeys to activate as and when they like. While enrichment systems for zoo animals have been around for some time, very few offer animals the ability to choose when and how they use the device, even though choice and control are known to promote animal welfare.
'We were very much interested in how we can give animals control over their ...
Reimagined US-Middle East strategy would lean less on arms sales, more on dev't/governance
2021-02-23
U.S. policies in the Middle East are built on outdated "legacy" aid packages, massive arms sales and a disproportionate focus on the Iranian threat that fail to advance American interests - or help the region's people - and need to be rethought, according to a new RAND Corporation report.
The United States devotes an overwhelming share of foreign military financing to just three countries - Israel, Egypt and Jordan, which received 81% of the $6 billion spent globally in 2019. If policymakers were to pursue an alternative strategy outlined by RAND researchers, ...
The magic angle of twisted graphene
2021-02-23
Graphene, a two-dimensional material composed exclusively of carbon, has revealed extraordinary properties, including thermal and electrical conductivity, transparency, and flexibility. When combined, these properties become particularly interesting in the age of touch screens and flexible electronics! 'Unlike 3D materials, graphene has a height reduced to the ultimate dimension of the atom. It's therefore a carbon atom plane,' explains Prof. Jean-Christophe Charlier, a specialist in nanoscopic physics at the Institute of Condensed Matter and Nanosciences of UCLouvain.
In a study published in Nature, the scientist and his team dissected the behaviour of electrons when two layers of graphene superimposed at an ...
Drifter or homebody? Study first to show where whitespotted eagle rays roam
2021-02-23
Its muscular body shape and large pectoral fins are perfect for long-distance travel, yet movement patterns of the whitespotted eagle ray (Aetobatus narinari) remain a mystery. Researchers from Florida Atlantic University's Harbor Branch Oceanographic Institute in collaboration with Mote Marine Laboratory & Aquarium, the University of Florida and the Florida Fish and Wildlife Conservation Commission, are the first to conduct a multiyear study examining large-scale movements of whitespotted eagle rays in United States waters.
Between 2016 and 2018, scientists fitted 54 rays with acoustic transmitters ...
Largest comprehensive Middle East GWAS reveals Arab genetic risk factors
2021-02-23
Doha, Qatar - (February 23, 2021) - A group of researchers at Qatar Foundation have reported the first and largest genetic association study in the Middle East, that has been published online in Nature Communications - a leading a peer-reviewed, open access, scientific journal published by Nature Research.
The study titled "Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits" highlights a vital piece of information wherein now there is a better understanding of the genetic risk factors that are specific to the Arab population, including those that are shared with other ethnicities.
Qatar was among the first countries to launch its own large-scale, national genome project. Qatar Genome ...
New features of a gene defect that affects muzzle length and caudal vertebrae in dogs
2021-02-23
A recent genetic study at the University of Helsinki provides new information on the occurrence of a DVL2 gene defect associated with a screw tail and its relevance to canine constitution and health. The variant was found in several Bulldog and Pit Bull type breeds, and it was shown to result in caudal vertebral anomalies and shortening of the muzzle. The DLV2 variant may also affect the development of the heart.
Dog breeding is often focused on appearance. In some breeds, the ideal body shape is bulky, with a broad head and short muzzle, short legs and a very short and kinked tail, also known as a "screw tail". In a previous study in the United States, screw tail was linked to a variant in the DVL2 gene. The variant has become enriched ...
Sustainable but smartly: Tackling security and privacy issues in smart agriculture
2021-02-23
According to recent estimates, there will be roughly 10 billion people to feed in 2050. Agricultural production will need to increase by almost 56% to guarantee food security globally, without converting more land for agriculture (in line with environmental and climate targets). This unprecedented challenge has ushered in the era of "smart agriculture," which promises to revolutionize food production by combining agricultural techniques with information technology, automation, and artificial intelligence. This new era, called "Agriculture 4.0," could ensure sustainable food production for the entire world. However, as communities gradually embrace smart agriculture, it is important to understand how to manage the security and privacy risks associated with the integration of ...
CDDEP report highlights tremendous burden from infectious diseases in SEAR countries
2021-02-23
Washington, DC / New Delhi, India - Researchers at CDDEP, in collaboration with leading experts in the field, have produced the "Infectious Diseases in the South-East Asia Region" report, which examines cross-boundary challenges in communicable disease control in countries in the South-and South-East Asia region. The report emphasizes infectious diseases related to other sources of disease burden in the region and communicates overall trends in the health and economic burden they impose.
Despite substantial progress in recent years, which has seen reductions in deaths from HIV and malaria and an increase ...
The invisible smallest particles matter for the air we breathe
2021-02-23
Researchers of the University of Helsinki have resolved for the first time, how the ultrafine particles of atmosphere effect on the climate and health.
Atmospheric air pollution kills more than 10,000 people every day. The biggest threat to human health has been assumed to be the mass accumulation of atmospheric particles with diameter smaller 2.5 μm: the higher the mass and loss of visibility, the bigger the threat.
The researchers of the Institute for Atmospheric and Earth System Research (INAR) at the University of Helsinki together with collaborators in China discovered that if we want to solve the accumulation of the biggest particles, we need to start with the smallest.
Until recent ...
Whale Sharks show remarkable capacity to recover from injuries
2021-02-23
A new study has for the first time explored the rate at which the world's largest fish, the endangered whale shark, can recover from its injuries. The findings reveal that lacerations and abrasions, increasingly caused through collisions with boats, can heal in a matter of weeks and researchers found evidence of partially removed dorsal fins re-growing.
This work, published in the journal Conservation Physiology, comes at a critical time for these large sharks, that can reach lengths of up to 18 metres. Other recent studies have shown that as their popularity within the wildlife tourism sector increases, so do interactions with humans and boat traffic. As a result, these ...
New therapeutic target for Huntington's treatment
2021-02-23
Huntington's disease is caused by a mutation in the Huntingtin gene (HTT), which appears in adults and features motor, cognitive and psychiatric alterations. The origin of this disease has been associated with the anomalous functioning of the mutated protein: mHTT, but recent data showed the involvement of other molecular mechanisms.
A new study conducted by the University of Barcelona has identified a type of ribonucleic acid (RNA) as a potential therapeutic target for the treatment of the disease. These are the small RNA, or sRNAs, molecules that do not code proteins but have important functions in the regulation of gene expression. According to the study, sRNAs would ...
Terahertz imaging of graphene paves the way to industrialisation
2021-02-23
X-ray scans revolutionised medical treatments by allowing us to see inside humans without surgery. Similarly, terahertz spectroscopy penetrates graphene films allowing scientists to make detailed maps of their electrical quality, without damaging or contaminating the material. The Graphene Flagship brought together researchers from academia and industry to develop and mature this analytical technique, and now a novel measurement tool for graphene characterisation is ready.
The effort was possible thanks to the collaborative environment enabled by the Graphene Flagship European consortium, with participation by scientists from Graphene Flagship partners DTU, Denmark, IIT, Italy, Aalto University, Finland, AIXTRON, UK, imec, Belgium, Graphenea, Spain, Warsaw ...
Seasonal variation in daylight influences brain function
2021-02-23
Seasons have an impact on our emotions and social life. Negative emotions are more subdued in the summer, whereas seasonal affective disorder rates peak during the darker winter months. Opioids regulate both mood and sociability in the brain.
In the study conducted at the Turku PET Centre, Finland, researchers compared how the length of daylight hours affected the opioid receptors in humans and rats.
"In the study, we observed that the number of opioid receptors was dependent on the time of the year the brain was imaged. The changes were most prominent in the brain regions that control emotions and sociability. The changes in the opioid receptors caused by the variation in the amount of daylight could be an important factor in seasonal affective disorder," ...
New sensor paves way to low-cost sensitive methane measurements
2021-02-23
WASHINGTON -- Researchers have developed a new sensor that could allow practical and low-cost detection of low concentrations of methane gas. Measuring methane emissions and leaks is important to a variety of industries because the gas contributes to global warming and air pollution.
"Agricultural and waste industries emit significant amounts of methane," said Mark Zondlo, leader of the Princeton University research team that developed the sensor. "Detecting methane leaks is also critical to the oil and gas industry for both environmental and economic reasons because natural gas is mainly composed of methane."
In ...
Hormone helps prevent muscle loss in mice on high fat diets, USC study finds
2021-02-23
A new study suggests that a hormone known to prevent weight gain and normalize metabolism can also help maintain healthy muscles in mice. The findings present new possibilities for treating muscle-wasting conditions associated with age, obesity or cancer, according to scientists from the University of Southern California Leonard Davis School of Gerontology.
The research, published this month in the American Journal of Physiology-Endocrinology and Metabolism, addresses the related problems of age and obesity-induced muscle loss, conditions which can lead to increased risk of falls, diabetes and other negative health impacts. It also adds to a growing number of findings describing beneficial effects of MOTS-c, ...
Don't focus on genetic diversity to save our species
2021-02-23
Scientists at the University of Adelaide have challenged the common assumption that genetic diversity of a species is a key indicator of extinction risk.
Published in the journal PNAS, the scientists demonstrate that there is no simple relationship between genetic diversity and species survival. But, Dr Joao Teixeira and Dr Christian Huber from the University of Adelaide's School of Biological Sciences conclude, the focus shouldn't be on genetic diversity anyway, it should be on habitat protection.
"Nature is being destroyed by humans at a rate never seen before," says computational biologist Dr Huber. "We burn ...
More than 87,000 scientific papers on coronavirus since pandemic
2021-02-23
COLUMBUS, Ohio - Scientists from around the world have published more than 87,000 papers about coronavirus between the start of the COVID-19 pandemic and October 2020, a new analysis shows.
Even given the importance of the pandemic, researchers were surprised by the huge number of studies and other papers that scientists produced on the subject in such a short time.
"It is an astonishing number of publications - it may be unprecedented in the history of science," said Caroline Wagner, co-author of the study and associate professor in the John Glenn College of Public Affairs at The Ohio State University.
"Nearly all of the scientific community around the world turned its attention to this one issue."
Wagner conducted the analysis with Xiaojing Cai from Zhejiang University in ...
New material is next step toward stable high-voltage long-life solid-state batteries
2021-02-23
A team of researchers designed and manufactured a new sodium-ion conductor for solid-state sodium-ion batteries that is stable when incorporated into higher-voltage oxide cathodes. This new solid electrolyte could dramatically improve the efficiency and lifespan of this class of batteries. A proof of concept battery built with the new material lasted over 1000 cycles while retaining 89.3% of its capacity--a performance unmatched by other solid-state sodium batteries to date.
Researchers detail their findings in the Feb. 23, 2021 issue of Nature Communications.
Solid state batteries hold the promise of safer, cheaper, and longer lasting batteries. Sodium-ion chemistries are particularly promising because sodium is low-cost and abundant, as opposed ...
Tool encoded in coronaviruses provides a potential target for COVID-19
2021-02-23
ROCKVILLE, MD - Coronaviruses exploit our cells so they can make copies of themselves inside us. After they enter our cells, they use our cell machinery to make unique tools of their own that help them generate these copies. By understanding the molecular tools that are shared across coronaviruses, there is potential to develop treatments that can not only work in the current COVID-19 pandemic, but in future coronavirus outbreaks as well. Rockefeller University researchers in the labs of Tarun Kapoor and Shixin Liu, including postdoctoral associate ...
How reducing body temperature could help a tenth of all ICU patients
2021-02-23
ROCKVILLE, MD - A tenth of all intensive care unit patients worldwide, and many critical patients with COVID-19, have acute respiratory distress syndrome (ARDS). Therapeutic hypothermia, an intentional cooling of the body, has been suggested as a way to improve ARDS. New research by Chiara Autilio and colleagues in the lab of Jesus Perez-Gil at the Complutense University of Madrid shows not only how therapeutic hypothermia works in the lungs at the molecular level, but also why it could be successfully applied to ARDS. Autilio and her colleagues' work was published in Nature Scientific Reports in January 2021 and will be presented ...
Scientists use DNA origami to monitor CRISPR gene targeting
2021-02-23
ROCKVILLE, MD - The remarkable genetic scissors called CRISPR/Cas9, the discovery that won the 2020 Nobel Prize in Chemistry, sometimes cut in places that they are not designed to target. Though CRISPR has completely changed the pace of basic research by allowing scientists to quickly edit genetic sequences, it works so fast that it is hard for scientists to see what sometimes goes wrong and figure out how to improve it. Julene Madariaga Marcos, a Humboldt postdoctoral fellow, and colleagues in the lab of Professor Ralf Seidel at Leipzig University in Germany, found a way to analyze the ultra-fast movements of CRISPR enzymes, which will help researchers understand how they recognize their target sequences in hopes of improving the specificity. Madariaga Marcos will present ...
ALS neuron damage reversed with new compound
2021-02-23
New compound targets neurons that initiate voluntary movement
After 60 days of treatment, diseased brain cells look like healthy cells
More research needed before clinical trial can be initiated
CHICAGO and EVANSTON--- Northwestern University scientists have identified the first compound that eliminates the ongoing degeneration of upper motor neurons that become diseased and are a key contributor to ALS (amyotrophic lateral sclerosis), a swift and fatal neurodegenerative disease that paralyzes its victims.
In addition to ALS, upper motor neuron degeneration also results in other motor neuron diseases, such as hereditary spastic paraplegia (HSP) and primary lateral sclerosis (PLS).
In ALS, movement-initiating nerve cells in the brain (upper motor neurons) and muscle-controlling ...
Research finds college students with ADHD are likely to experience significant challenges
2021-02-23
According to a 2017 UCLA study, students with ADHD make up about 6% of the college student population and represent the most common type of disability supported by college disability offices. But are these students receiving enough academic support from their institutions? Despite ADHD being prevalent among college students, there has been little research focused on how having ADHD impacts the transition to college and ongoing academic success. Until now.
New research from George DuPaul, professor of school psychology and associate dean for research in Lehigh University's College of Education, and colleagues confirms students with ADHD face consequential challenges in succeeding and completing ...
Climate impacts drive east-west divide in forest seed production
2021-02-23
DURHAM, N.C. -- Younger, smaller trees that comprise much of North America's eastern forests have increased their seed production under climate change, but older, larger trees that dominate forests in much of the West have been less responsive, a new Duke University-led study finds.
Declines in these trees' seed production, or fecundity, could limit western forests' ability to regenerate following the large-scale diebacks linked to rising temperatures and intensifying droughts that are now occurring in many states and provinces.
This continental divide, reported for the ...
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