A new neural network developed by researchers at the University of Eastern Finland and Kuopio University Hospital enables an easy and accurate assessment of sleep apnoea severity in patients with cerebrovascular disease. The assessment is automated and based on a simple nocturnal pulse oximetry, making it possible to easily screen for sleep apnoea in stroke units. Up to 90% of patients experiencing a stroke have sleep apnoea, according to earlier studies conducted at Kuopio University Hospital. If left untreated, sleep apnoea can reduce the quality of life and rehabilitation of patients with stroke and increase ...

An estimated 48 million cases of foodborne illness are contracted in the United States every year, causing about 128,000 hospitalizations and 3,000 deaths, according to the Centers for Disease Control (CDC). In some instances, the source is well known, such as a batch of tainted ground beef that infected 209 people with E. Coli in 2019. But 80 percent of food poisoning cases are of unknown origin, making it impossible to inform consumers of hazardous food items. David Goldberg, assistant professor of management information systems at San Diego State University, wants to improve the traceability and ...

Overview: Phycocyanobilin (PCB) is a natural blue chromophore found in cyanobacteria. PCB is expected to be applied as food colorants and pharmaceuticals with anti-inflammatory and antioxidant properties. PCB also functions as the chromophore of photoswitches that control biological functions in synthetic biology. PCB is covalently bound to phycocyanin, a component of photosynthetic antenna protein, and its extraction requires specialized expertise, time-consuming procedures, and/or expensive reagents. A research group led by Assistant Professor Yuu Hirose at Toyohashi University of Technology succeeded in developing a highly efficient and rapid extraction method for PCB by treating cyanobacterial cells with alcohol ...

The use of online messaging and social media apps among Singapore residents has spiked during the COVID-19 pandemic, a Nanyang Technological University, Singapore (NTU Singapore) study has found. Three in four respondents (75%) said that their use of WhatsApp during the pandemic increased. This was followed by Telegram (60.3%), Facebook (60.2%) and Instagram (59.7%). Accompanying this spike is videoconferencing fatigue, found the NTU Singapore study, which surveyed 1,606 Singapore residents from 17 to 31 December last year. Nearly one in two Singapore residents (44%) said they felt drained from videoconferencing activities, which ...

Utilizing a newly developed state-of-the-art synchrotron technique, a group of scientists led by Dr. Ho-kwang Mao, Director of HPSTAR, conducted the first-ever high-pressure study of the electronic band and gap information of solid hydrogen up to 90 GPa. Their innovative high pressure inelastic X-ray scattering result serves as a test for direct measurement of the process of hydrogen metallization and opens a possibility to resolve the electronic dispersions of dense hydrogen. This work is published in the recent issue of Physical Review Letters. The pressure-induced evolution of hydrogen's electronic band from a wide gap insulator to a closed gap metal, or metallic ...

A group of KAIST researchers and collaborators have engineered a tiny brain implant that can be wirelessly recharged from outside the body to control brain circuits for long periods of time without battery replacement. The device is constructed of ultra-soft and bio-compliant polymers to help provide long-term compatibility with tissue. Geared with micrometer-sized LEDs (equivalent to the size of a grain of salt) mounted on ultrathin probes (the thickness of a human hair), it can wirelessly manipulate target neurons in the deep brain using light. This study, led by Professor Jae-Woong Jeong, is a step forward from the wireless head-mounted ...

The prevalence of inflammatory bowel diseases has significantly increased both in Finland and globally. These disorders cannot be entirely cured. Instead, they are treated with anti-inflammatory drugs and, at times, through surgery. If conventional drug therapies based on anti-inflammatory drugs are ineffective, the diseases can be treated using infliximab, a biological TNF-α blocker that is administered intravenously. Infliximab is an antibody that prevents TNF-α, a pro-inflammatory factor, from binding with inflammatory cells in the intestine. It is effective in reducing inflammation and improving the patient's condition, while also controlling the disease well. Although infliximab therapy is often effective, roughly 30-40% of patients either do not respond ...

An international research team succeeded in gaining new insights into the artificially produced superheavy element flerovium, element 114, at the accelerator facilities of the GSI Helmholtzzentrum für Schwerionenforschung in Darmstadt, Germany. Under the leadership of Lund University in Sweden and with significant participation of Johannes Gutenberg University Mainz (JGU) as well as the Helmholtz Institute Mainz (HIM) in Germany and other partners, flerovium was produced and investigated to determine whether it has a closed proton shell. The results suggest that, contrary to expectations, flerovium is not a so-called "magic nucleus". The results were published in ...

Two family members test positive for COVID-19 -- how do we know who infected whom? In a perfect world, network science could provide a probable answer to such questions. It could also tell archaeologists how a shard of Greek pottery came to be found in Egypt, or help evolutionary biologists understand how a long-extinct ancestor metabolized proteins. As the world is, scientists rarely have the historical data they need to see exactly how nodes in a network became connected. But a new paper published in Physical Review Letters offers hope for reconstructing the missing information, using a new method to evaluate the rules that generate network models. "Network models are like impressionistic ...

A new paper from UC Santa Cruz researchers, published in END ...

Overview: Jihui Yuan (Assistant Professor, Department of Architecture and Civil Engineering, Toyohashi University of Technology) proposed a numerical bead model to predict the upward-to-downward reflection ratio of glass bead retro-reflective (RR) material purposed for urban heat island (UHI) mitigation and reducing energy consumption. It revealed that the retro-reflectivity of glass bead RR material gradually increases from morning to noon, at which time it begins to gradually decrease. These results will contribute to existing research on the absorption or reflection of solar radiation to improve urban thermal and lighting ...

WASHINGTON--Poor social conditions caused by systemic racism contribute to health disparities in people with diabetes, according to a paper published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. Minorities are disproportionately affected by diabetes because of poor social conditions that contribute to negative health outcomes such as poverty, unsafe housing, lack of access to healthy food and safe physical activity, and inadequate employment and educational opportunities. These are known as the social determinants of health and are the result of residential ...

PITTSBURGH, 26 January 2021 - A vaginal ring containing the antiretroviral drug dapivirine and the contraceptive hormone levonorgestrel delivered sustained levels of each drug when used continuously for 90 days - levels likely sufficient to serve its dual purpose for protecting against both HIV and unwanted pregnancy, according to findings of a new study. Results of the Phase I study of the 90-day dual-purpose ring are being presented at the HIV Research for Prevention (HIVR4P) Virtual Conference, or HIVR4P // Virtual, which is taking place over the course of ...

"Shell-crushing" - exactly what it sounds like - is a predatory mode used by numerous marine life from crabs to octopuses to large fishes and mammals when they eat hard-shelled mollusks like clams, oysters and conchs. These predators have to break apart the shell using robust claws or fortified jaws to access the prey's soft tissues. Despite its prevalence in the marine environment, this feeding behavior has remained elusive to study remotely, particularly for larger marine animals that destroy shells almost completely, leaving behind little trace. Moreover, because they are highly mobile, scientists have difficulty in directly observing their foraging habits, which is why the ecology of shell-crushing (durophagy) remains ...

Tokyo, Japan - Researchers from Tokyo Metropolitan University have created a new tungsten-substituted vanadium oxide catalyst for breaking down harmful nitrogen oxides in industrial exhaust. Their new catalyst material works at lower temperatures and does not suffer major drops in performance when processing "wet" exhaust, resolving a major drawback in conventional vanadium oxide catalysts. They found that the unaggregated dispersal of atomic tungsten in the original crystal structure plays a key role in how it functions. Selective catalytic reduction (SCR) is an essential technology for keeping air clean. Industrial exhaust is passed through catalytic units and reacted with ...

If we are to prevent the impending environmental crisis, it is imperative that we find efficient and sustainable ways to avoid being wasteful. One area with much room for improvement is the recycling of waste heat from industrial processes and technological devices into electricity. Thermoelectric materials are at the core of research in this field because they allow for clean power generation at little cost. For thermoelectric materials to be used in vastly different fields such as steel works and transportation, they need to be able to operate in both high and low temperature regimes. In this regard, "half-Heusler Ni-based ...

VANCOUVER, Wash. -When entrepreneurs dream up ideas for new businesses, cannabis use might help, and hinder, their creativity, according to a new study in the Journal of Business Venturing by Washington State University researchers. The study found that cannabis-using entrepreneurs generated new business ideas such as a weightless, gravity-free virtual reality workout, that were more original, but less feasible, compared to those who do not use cannabis. "Originality and feasibility are both crucial in entrepreneurship--one without the other limits potential value creation," said Benjamin Warnick, lead author of the study and assistant professor in the ...

LONDON, ON - Neurofeedback, also called 'brain training,' consists of exercises where individuals regulate their own brain activity. In a new study from Lawson Health Research Institute and Western University, researchers have found that neurofeedback may be an effective treatment for individuals with post-traumatic stress disorder (PTSD). Published in END ...

A new study found that talented dogs can learn new words after hearing them only four times. While preliminary evidence seems to show that most dogs do not learn words (i.e. names of objects), unless eventually very extensively trained, a few individuals have shown some exceptional abilities. The Family Dog Project research team at the Department of Ethology, Eötvös Loránd University, Budapest is investigating on these exceptionally talented dogs who seem to learn words in the absence of any formal training, but simply by being exposed to playing with their owners in the typical way ...

Toddlers with high daily touchscreen use are quicker to look at objects when they appear and are less able to resist distraction compared to toddlers with no or low touchscreen use - according to new research from Birkbeck, University of London, King's College London and University of Bath. The research team say the findings are important for the growing debate around the role of screen time on toddlers' development especially given the increased levels of screen time seen during the COVID-19 pandemic. Lead researcher Professor Tim Smith, from Birkbeck's ...

New research from Queen Mary University of London and the University of Maryland, has reignited the debate around the behaviour of the giant dinosaur Spinosaurus. Since its discovery in 1915, the biology and behaviour of the enormous Spinosaurus has puzzled palaeontologists worldwide. It was recently argued that the dinosaur was largely an aquatic predator, using its large tail to swim and actively pursue fish in the water. The new study, published today in Palaeontologia Electronica, challenges this recent view of Spinosaurus suggesting that whilst it likely fed ...

Philadelphia, January 26, 2021 - Addiction, or substance use disorder (SUD), is a complex neurological condition that includes drug-seeking behavior among other cognitive, emotional and behavioral features. Synaptic plasticity, or changes in the way neurons communicate with one another, drives these addictive behaviors. These lasting brain changes are at the crux of why addiction is so hard to treat. A new study in Biological Psychiatry, published by Elsevier, now shows that players in the extracellular environment - not just at neuronal interfaces - contribute to addiction plasticity. Neurons in a brain area called the nucleus accumbens are known to undergo addiction-related plasticity. Specifically, changes at synapses of medium spiny neurons (MSN), which sense the ...

By 2020, massive losses of large populations of corals have been observed throughout Florida and into the greater Caribbean basin. Taking into account the high mortality and the large number of susceptible species affected, this is likely the most lethal case of Stony Coral Tissue Loss Disease (SCTLD) ever recorded in modern history. However, for too long, the tremendous decline in coral reefs has wrongly been attributed to the local dredge project, which had been ongoing at the time of the initial reports. In a recent Perspectives paper, END ...

Philadelphia, January 26, 2021 - Researchers at Children's Hospital of Philadelphia (CHOP) and the University of Pennsylvania found female and male collegiate athletes take approximately the same amount of time to recover from a concussion, with subtle differences in recovery time depending on the type of sports being played and the division level of the sport. The findings suggest that equity in access to sports medical care among college athletes may be contributing to these similar outcomes. The findings, derived as part of the CARE (Concussion Assessment, Research and Education) Consortium, ...

New research coming out of UBC's Okanagan campus may take the current 'gold standard' for heart valves to a new level of reliability. A team of researchers at UBCO's Heart Valve Performance Lab (HVPL) has developed a way to improve overall blood flow through the valves, so the design of mechanical heart valves will more closely match the real thing. "Despite more than 40 years of research, we are still chasing the goal of creating mechanical heart valves that perform consistently and seamlessly inside the human body," explains Dr. Hadi Mohammadi, an associate professor ...