International team used the stomach bacteria Helicobacter pylori as a biomarker for ancient human migrations DNA sequences catalogued at University of Warwick in EnteroBase, a public genomes database, demonstrate that a migration of Siberians to the Americas occurred approximately 12,000 years ago Project began in 2000s but new statistical techniques allowed researchers to reconstruct and date the migrations of Siberian Helicobacter pylori Early migrations of humans to the Americas from Siberia around 12,000 years ago have been traced using the bacteria they carried by an international team including scientists at the University of ...

Certain patients with an aggressive form of ovarian cancer have a better chance of a cure through surgical removal of their tumor before chemotherapy instead of the reverse, a new study shows. Led by researchers at NYU Grossman School of Medicine, Perlmutter Cancer Center, and Dana-Farber Cancer Institute, the study used a mathematical tool to examine how doctors should coordinate available treatments for high-grade serous ovarian cancer (HGSC). Ovarian cancer is the 8th most common cancer and cancer death in women worldwide, and HGSC constitutes roughly 70 percent of ovarian malignancies and has the worst prognosis. Patients with the condition typically undergo surgery and chemotherapy, but there has been long-standing controversy over the best order of treatment. Published ...

A study of woodland ecosystems that provide habitat for rare and endangered species along streams and rivers throughout California reveals that some of these ecologically important areas are inadvertently benefitting from water that humans are diverting for their own needs. Though it seems a short-term boon to these ecosystems, the artificial supply creates an unintended dependence on its bounty, threatens the long-term survival of natural communities and spotlights the need for changes in the way water is managed across the state. "We need to be more intentional in incorporating ecosystem water needs when we manage water--both for aquatic organisms and species on land," said Melissa Rohde, the lead author of a study published June ...

The concentration of potentially toxic metals is increasing in the population of the franciscana dolphin --a small cetacean, endemic from the Rio de la Plata and an endangered species-- according to a study led by a team of the Faculty of Biology and the Biodiversity Research Institute (IRBio), published in the journal Science of The Total Environment. The impact of human activity in the region could be the cause for the increase of trace elements such as chromium, copper, iron and nickel in the dolphins' biological tissues, as stated in the study. The paper counts on the participation of members from the National History Museum of Uruguay, and is subsidized through a project of ...

LAWRENCE -- The United States has the highest population of incarcerated citizens among developed nations. Every year, roughly 2 million women, the majority held in jails, leave incarceration. The COVID-19 pandemic hit jails and correctional facilities harder than almost any other societal setting. Many of the people leaving incarceration are returning to communities that were also disproportionately affected by the pandemic, yet many people in that population have expressed hesitancy to receive a COVID-19 vaccine. New research from the University of Kansas found high rates of vaccine hesitancy among women transitioning from incarceration, due to a multitude ...

Syracuse, N.Y. - A study of nearly 550 adults with intellectual and developmental disabilities receiving residential services in New York City found that age, larger residential settings, Down syndrome and chronic kidney disease were the most common risk factors for COVID-19 diagnosis, and heart disease was most associated with COVID-19 deaths. The study, "Risk Factors Associated With COVID-19 Outcomes Among People With Intellectual and Developmental Disabilities Receiving Residential Services," was published June 8 by JAMA Network Open and provided the first evidence of the risk factors leading to COVID-19 diagnosis and death among people with IDD who receive residential services. The study's findings suggest that ...

Fully occupied intensive care units (ICUs). Physically and mentally exhausted health workers. Chaotically overcrowded hospitals. These and similar problems posed by the COVID-19 pandemic in Brazil have created ideal conditions for the emergence of Candida auris, a microorganism some are calling a "superfungus" because of the speed with which it has developed drug resistance. The first two cases were confirmed in December 2020 at a hospital in Salvador (state of Bahia, Northeast Brazil), and are described in the Journal of Fungi by a group of researchers led by Arnaldo Colombo, head of the Special Mycology Laboratory at the Federal University of São Paulo (UNIFESP). The study was supported by São Paulo Research Foundation - FAPESP. "Nine other C. auris patients ...

TROY, N.Y. -- The future of quantum computing may depend on the further development and understanding of semiconductor materials known as transition metal dichalcogenides (TMDCs). These atomically thin materials develop unique and useful electrical, mechanical, and optical properties when they are manipulated by pressure, light, or temperature. In research published today in Nature Communications, engineers from Rensselaer Polytechnic Institute demonstrated how, when the TMDC materials they make are stacked in a particular geometry, the interaction that occurs between particles gives researchers more control over the devices' properties. Specifically, the interaction between ...

A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression. The study, "Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure," is published in the journal Translational Psychiatry by researchers at UIC's Center for Alcohol Research in Epigenetics. "During withdrawal from long-term alcohol use, people often suffer from depression, which may cause them to start drinking again as a way to self-medicate. If we ...

The spin of the Milky Way's galactic bar, which is made up of billions of clustered stars, has slowed by about a quarter since its formation, according to a new study by researchers at University College London (UCL) and the University of Oxford. For 30 years, astrophysicists have predicted such a slowdown, but this is the first time it has been measured. The researchers say it gives a new type of insight into the nature of dark matter, which acts like a counterweight slowing the spin. In the study, published in the Monthly Notices of the Royal Astronomical Society, researchers analysed Gaia space telescope observations of a large group of stars, the Hercules stream, which are in resonance with the bar - that is, they revolve around the galaxy ...

An international team of researchers led by the University of Bonn (Germany) has identified the cause of a rare, severe muscle disease. According to these findings, a single spontaneously occurring mutation results in the muscle cells no longer being able to correctly break down defective proteins. As a result, the cells perish. The condition causes severe heart failure in children, accompanied by skeletal and respiratory muscle damage. Those affected rarely live beyond the age of 20. The study also highlights experimental approaches for potential treatment. Whether this hope will be fulfilled, however, will only become clear in a few years. The results are published in the journal Nature ...

A funny thing happened on the way to discovering how zinc impacts kidney stones - two different theories emerged, each contradicting the other. One: Zinc stops the growth of the calcium oxalate crystals that make up the stones; and two: It alters the surfaces of crystals which encourages further growth. Now it can be told - both theories are correct as reported in the America Chemical Society journal Crystal Growth & Design by Jeffrey Rimer, Abraham E. Dukler Professor of Chemical and Biomolecular Engineering at the University of Houston, who conducted the first study to offer some resolution to the differing hypotheses. "What we see with zinc is something ...

Our ability to confront global crises, from pandemics to climate change, depends on how we interact and share information. Social media and other forms of communication technology restructure these interactions in ways that have consequences. Unfortunately, we have little insight into whether these changes will bring about a healthy, sustainable and equitable world. As a result, researchers now say that the study of collective behavior must rise to a "crisis discipline," just like medicine, conservation and climate science have done, according to a new paper published June 14 in the Proceedings of the National Academy of ...

(Santa Barbara, Calif.) -- Scientists at UC Santa Barbara, University of Southern California (USC), and the biotechnology company Regenerative Patch Technologies LLC (RPT) have reported new methodology for preservation of RPT's stem cell-based therapy for age-related macular degeneration (AMD). The new research, recently published in Scientific Reports, optimizes the conditions to cryopreserve, or freeze, an implant consisting of a single layer of ocular cells generated from human embryonic stem cells supported by a flexible scaffold about 3x6 mm in size. ...

When lithium ions flow in and out of a battery electrode during charging and discharging, a tiny bit of oxygen seeps out and the battery's voltage - a measure of how much energy it delivers - fades an equally tiny bit. The losses mount over time, and can eventually sap the battery's energy storage capacity by 10-15%. Now researchers have measured this super-slow process with unprecedented detail, showing how the holes, or vacancies, left by escaping oxygen atoms change the electrode's structure and chemistry and gradually reduce how much energy it can store. The results contradict some of the assumptions scientists had made about this process and could suggest new ways of engineering electrodes to prevent it. The research team from the Department of Energy's ...

MISSOULA - Those in love with the outdoors can spend their entire lives chasing that perfect campsite. New University of Montana research suggests what they are trying to find. Will Rice, a UM assistant professor of outdoor recreation and wildland management, used big data to study the 179 extremely popular campsites of Watchman Campground in Utah's Zion National Park. Campers use an online system to reserve a wide variety of sites with different amenities, and people book the sites an average of 51 to 142 days in advance, providing hard data about demand. Along with colleague Soyoung Park of Florida Atlantic University, Rice sifted through nearly 23,000 reservations. The researchers found that price and availability of electricity were the largest drivers of demand. Proximity ...

Albeit very small, with a carapace width of only 3 cm, the Atlantic mangrove fiddler crab Leptuca thayeri can be a great help to scientists seeking to understand more about the effects of global climate change. In a study published in the journal Estuarine, Coastal and Shelf Science, Brazilian researchers supported by São Paulo Research Foundation - FAPESP show how the ocean warming and acidification forecast by the end of the century could affect the lifecycle of these crustaceans. Embryos of L. thayeri were exposed to a temperature rise of 4 °C and a pH reduction of 0.7 against the average for their habitat, growing faster as a result. However, a larger number of ...

An interdisciplinary group of researchers from across the globe has comprehensively examined the sources and health effects of air pollution -- not just on a global scale, but also individually for more than 200 countries. They found that worldwide, more than one million deaths were attributable to the burning of fossil fuels in 2017. More than half of those deaths were attributable to coal. Findings and access to their data, which have been made public, were published today in the journal Nature Communications. Pollution is at once a global crisis and a devastatingly personal problem. It is analyzed by satellites, but PM2.5 -- tiny particles that can infiltrate a person's lungs -- can also sicken a person who cooks dinner nightly on a cookstove. "PM2.5 ...

Treatment options for a deadly liver cancer, fibrolamellar carcinoma, are severely lacking. Drugs that work on other liver cancers are not effective, and although progress has been made in identifying the specific genes involved in driving the growth of fibrolamellar tumors, these findings have yet to translate into any treatment. For now, surgery is the only option for those affected--mostly children and young adults with no prior liver conditions. Sanford M. Simon and his group understood that patients dying of fibrolamellar could not afford to wait. "There are people who need therapy now," he says. So his group threw the kitchen sink at the problem and tested over 5,000 compounds, either already approved for other clinical uses or in clinical ...

DALLAS - June 14, 2021 - Overweight cancer patients receiving immunotherapy treatments live more than twice as long as lighter patients, but only when dosing is weight-based, according to a study by cancer researchers at UT Southwestern Medical Center. The findings, published in the Journal for ImmunoTherapy of Cancer, run counter to current practice trends, which favor fixed dosing, in which patients are given the same dose regardless of weight. The study included data on nearly 300 patients with melanoma, lung, kidney, and head and neck cancers ...

Leesburg, VA, June 14, 2021--According to ARRS' American Journal of Roentgenology (AJR), high-dose intranodal lymphangiography (INL) with ethiodized oil is a safe and effective procedure for treating high-output postsurgical chylothorax with chest tube removal in 83% of patients. "To our knowledge," wrote corresponding author Geert Maleux of University Hospitals in Leuven, Belgium, "no data are available on the safety or potential beneficial effect of injecting higher doses of ethiodized oil to treat patients with refractory postoperative chylothorax." All 18 patients (mean, 67 years; range, ...

A team of scientists from Kaunas University of Technology and Lithuanian Energy Institute proposed a method to convert lint-microfibers found in clothes dryers into energy. They not only constructed a pilot pyrolysis plant but also developed a mathematical model to calculate possible economic and environmental outcomes of the technology. Researchers estimate that by converting lint microfibers produced by 1 million people, almost 14 tons of oil, 21.5 tons of gas and nearly 10 tons of char could be produced. Each year, the global population consumes approximately 80 billion pieces of clothing and approximately €140 million worth of it goes into landfill. This is accompanied by large amounts of emissions, causing serious environmental and health problems. One of the ways to lessen ...

A new study found higher education students are more engaged and motivated when they are taught using playful pedagogy rather than the traditional lecture-based method. The study was conducted by University of Colorado Denver counseling researcher Lisa Forbes and was published in the Journal of Teaching and Learning. While many educators in higher education believe play is a method that is solely used for elementary education, Forbes argues that play is important in post-secondary education to enhance student learning outcomes. Throughout the spring 2020 semester, Forbes observed students who were enrolled in three of her courses between the ages of 23-43. To introduce playful pedagogy, Forbes included games and play, not always tied to the ...

Solar flares jetting out from the sun and thunderstorms generated on Earth impact the planet's ionosphere in different ways, which have implications for the ability to conduct long range communications. A team of researchers working with data collected by the Incoherent Scatter Radar (ISR) at the Arecibo Observatory, satellites, and lightning detectors in Puerto Rico have for the first time examined the simultaneous impacts of thunderstorms and solar flares on the ionospheric D-region (often referred to as the edge of space). In the first of its kind analysis, the team determined that solar flares ...

The types of land around us play an important role in how major storms will unfold -- flood waters may travel differently over rural versus urban areas, for example. However, it's challenging to get an accurate picture of land types using only satellite image data because it is so difficult to interpret. Researchers at the Cockrell School of Engineering have, for the first time, applied a machine learning algorithm to measure the surface roughness of different types of land with a high level of detail. The team used a type of satellite imagery that is more dependable and easier to capture than typical optical photographs but also more challenging to analyze. And they are working to integrate this data into storm surge models to give a clearer ...