FOR IMMEDIATE RELEASE In what turned out to be one of the most important accidents of all time, Scottish bacteriologist Alexander Fleming returned to his laboratory after a vacation in 1928 to find a clear zone surrounding a piece of mold that had infiltrated a petri dish full of Staphylococcus aureus (S. aureus), a common skin bacterium he was growing. That region of no bacterial growth was the unplanned birth of a medical miracle, penicillin, and would lead to the era of antibiotics. Now, END ...

When gravitational waves were first detected in 2015 by the advanced Laser Interferometer Gravitational-Wave Observatory (LIGO), they sent a ripple through the scientific community, as they confirmed another of Einstein's theories and marked the birth of gravitational wave astronomy. Five years later, numerous gravitational wave sources have been detected, including the first observation of two colliding neutron stars in gravitational and electromagnetic waves. As LIGO and its international partners continue to upgrade their detectors' sensitivity to gravitational waves, they will be able to probe a larger volume of the universe, thereby making the detection ...

As the COVID-19 pandemic wanes in the U.S., a new study from the University of Maryland School of Medicine (UMSOM) and University of Maryland Medical Center (UMMC) finds that hospitals nationwide may not be adequately prepared for the next pandemic. A 10-year analysis of hospitals' preparedness for pandemics and other mass casualty events found only marginal improvements in a measurement to assess preparedness during the years leading up to the COVID-19 pandemic. The study was published last month in the Journal of Healthcare Management. "Our work links objective healthcare data to a hospital score that ...

If a virtual world has ever left you feeling nauseous or disorientated, you're familiar with cybersickness, and you're hardly alone. The intensity of virtual reality (VR)--whether that's standing on the edge of a waterfall in Yosemite or engaging in tank combat with your friends--creates a stomach-churning challenge for 30-80% of users. In a first-of-its kind study, researchers at the University of Maryland recorded VR users' brain activity using electroencephalography (EEG) to better understand and work toward solutions to prevent cybersickness. The research was conducted by Eric Krokos, who received his Ph.D. in computer science in 2018, and Amitabh Varshney, a professor of computer science ...

Although wastewater disposal has been the primary driving force behind increased earthquake activity in southern Kansas since 2013, a new study concludes that the disposal has not significantly changed the orientation of stress in the Earth's crust in the region. Activities like wastewater disposal can alter pore pressure, shape and size within rock layers, in ways that cause nearby faults to fail during an earthquake. These effects are thought to be behind most recent induced earthquakes in the central and eastern United States. It is possible, however, that human activity could also lead to earthquakes by altering the orientation of stresses that act on faults in the region, said U.S. Geological Survey seismologist ...

As more evidence emerges that opioid overdose deaths have increased dramatically since the onset of COVID-19, the Centre for Addiction and Mental Health (CAMH), in collaboration with subject matter experts and medical regulatory authorities across Canada, have now released updated national clinical guidelines for the treatment of opioid use disorder. END ...

When someone is suspected of criminal activity, one of the most important questions they are asked is if they have a credible alibi. Playing back past events in our minds, however, is not like playing back a video recording. Recollections of locations, dates, and companions can become muddled with the passage of time. If a suspect's memories are out of line with documented events, a once-plausible alibi can crumble and may be seen as evidence of guilt. To put people's memories of past whereabouts to the test, a team of researchers tracked the locations of 51 volunteers for one month and found that their recollections were wrong approximately 36% of the time. "This is the first study to examine memory for where ...

Uppsala University scientists have designed a new mouse model that facilitates study of factors contributing to the progression of human bladder cancer and of immune-system activation when the tumour is growing. Using this model, they have been able to study how proteins change before, while and after a tumour develops in the bladder wall. The study has now been published in the scientific journal PLOS ONE. "The model was designed both to contain specific oncogenes, as they're called -- mutations that can drive tumour growth -- and to show a high incidence of harmful mutations, which we often see in people who get bladder cancer. These harmful mutations arise because of smoking, for instance, which is ...

Sudanese Islamic burial sites are distributed according to large-scale environmental factors and small-scale social factors, creating a galaxy-like distribution pattern, according to a study published July 7, 2021 in the open-access journal PLOS ONE by Stefano Costanzo of the University of Naples "L'Orientale" in Italy and colleagues. The Kassala region of eastern Sudan is home to a vast array of funerary monuments, from the Islamic tombs of modern Beja people to ancient burial mounds thousands of years old. Archaeologists don't expect these monuments are randomly placed; their ...

GPS data from cell phones may provide insight into how city inhabitants are using their urban greenspaces, in a study published July 7, 2021 in the open-access journal PLOS ONE by Meghann Mears and Paul Brindley from the University of Sheffield, UK, and colleagues. Urban greenspaces confer a range of health and well-being benefits on city inhabitants and provide connection to nature. In this study, Mears and colleagues use cellphone GPS data to assess how frequently residents of the city of Sheffield in the UK engage with their local urban greenspaces, and whether this engagement was different across demographic groups. The authors used the "Shmapped" app, developed as part of the Improving Well-being through Urban Nature project, to track how frequently 240 users based in Sheffield ...

New iguanodon-like dinosaur identified from jawbone fossil from Spain was likely a 6-8m long herbivore, closely related to species found in modern-day China and Niger. INFORMATION: Article Title: A new Styracosternan hadrosauroid (Dinosauria: Ornithischia) from the Early Cretaceous of Portell, Spain Funding: The authors received no specific funding for this work. Competing Interests: The authors have declared that no competing interests exist. Article URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0253599 ...

Brain microstructure may help explain the benefits of physical activity on cognition in older adults, according to MRI scans of 318 brains post-mortem. INFORMATION: Article Title: Physical activity, brain tissue microstructure, and cognition in older adults Funding: This work was supported in part by the National Institute on Aging (https://www.nia.nih.gov) grants K25 AG61254 (RJD), K01 AG64044 (VNP), K01 AG50823 (BDJ), R01 AG17917 (DAB), R01 AG47976 (ASB), R01 AG56352 (ASB), R01 AG64233 (JAS, KA), and P30 AG10161 (DAB), the National Institute of Neurological Disorders and Stroke (https://www.ninds.nih.gov) grant UH3 NS100599 ...

HOUSTON - (July 7, 2021) - A thin shell of soft polymer can help keep knotty ceramic structures from shattering, according to materials scientists at Rice University. Ceramics made with 3D printers crack under stress like any plate or bowl. But covered in a soft polymer cured under ultraviolet light, the same materials stand a far better chance of keeping their structural integrity, much like a car windshield's treated glass is less likely to shatter. The research at Rice's Brown School of Engineering, which appears in Science Advances, demonstrates the concept on schwarzites, complex lattices that for decades existed only as theory but can now be made with 3D printers. With added polymers, they come to resemble structures ...

Microscopists have long sought to find a way to produce high-quality, deep-tissue imaging of living subjects in a timely fashion. Until now, they had to choose between image quality or speed when it comes to looking into the inner workings of complex biological systems. Such a development would have a powerful impact on researchers in biology and in neuroscience, experts say. Now Dushan N. Wadduwage, a John Harvard Distinguished Science Fellow in Imaging at the FAS Center of Advanced Imaging, along with a team from MIT, detailed a new technique that would make that possible in a report in Science Advances. In the paper, the team presents a new process that uses computational imaging to get high resolution images at a rate 100 to 1,000 times faster than other state-of-the-art ...

Increased acidity in the atmosphere is disrupting the ecological balance of the oceans, according to new research led by the University of East Anglia (UEA). The first study to look at acidity's impact on nutrient transport to the ocean demonstrates that the way nutrients are delivered affects the productivity of the ocean and its ability to absorb CO2 from the atmosphere. The research, 'Changing atmospheric acidity as a modulator of nutrient deposition and ocean biogeochemistry', is published today in Science Advances. The analysis was carried out by an international team of experts, sponsored by the United Nations Group of Experts on the Scientific Aspects of Marine Environmental Protection (GESAMP). Prof Alex Baker, professor of marine and atmospheric chemistry ...

To create high-resolution, 3D images of tissues such as the brain, researchers often use two-photon microscopy, which involves aiming a high-intensity laser at the specimen to induce fluorescence excitation. However, scanning deep within the brain can be difficult because light scatters off of tissues as it goes deeper, making images blurry. Two-photon imaging is also time-consuming, as it usually requires scanning individual pixels one at a time. A team of MIT and Harvard University researchers has now developed a modified version of two-photon imaging that can image deeper within tissue and perform the imaging much more quickly than what was previously possible. This kind of imaging could allow scientists to more rapidly obtain ...

Metastatic tumors originating from notoriously aggressive triple-negative breast cancer that emerge in the lungs contain a more diverse array of cancer cells than those that arise in the liver, according to a new study in mice and organs from deceased cancer patients. The study also identified a set of genes that distinguish lung and liver metastases; together, the findings may inform future research on how targeted therapies impact tumors across various microenvironments. While scientists have known that the presence of distinct tumor cell populations within the same tumor drives breast cancer progression, it has not been fully understood why this dangerous cellular diversity develops within some tumors and not others. To investigate ...

From above, the Antarctic Ice Sheet might look like a calm, perpetual ice blanket that has covered Antarctica for millions of years. But the ice sheet can be thousands of meters deep at its thickest, and it hides hundreds of meltwater lakes where its base meets the continent's bedrock. Deep below the surface, some of these lakes fill and drain continuously through a system of waterways that eventually drain into the ocean. Now, with the most advanced Earth-observing laser instrument NASA has ever flown in space, scientists have improved their maps of these hidden lake systems under the West Antarctic ice sheet--and ...

"Equal pay for equal work," a motto touted by many people, turns out to be relevant to the plant world as well. According to new research by Stanford University ecologists, plants allocate resources to their microbial partners in proportion to how much they benefit from that partnership. "The vast majority of plants rely on microbes to provide them with the nutrients they need to grow and reproduce," explained Brian Steidinger, a former postdoctoral researcher in the lab of Stanford ecologist, Kabir Peay. "The problem is that these microbes differ in how well they do the job. We wanted to see how the plants reward their microbial employees." In a new study, published July 6 in the journal American Naturalist, the researchers investigated ...

Very recently, researchers led by Markus Aspelmeyer at the University of Vienna and Lukas Novotny at ETH Zurich cooled a glass nanoparticle into the quantum regime for the first time. To do this, the particle is deprived of its kinetic energy with the help of lasers. What remains are movements, so-called quantum fluctuations, which no longer follow the laws of classical physics but those of quantum physics. The glass sphere with which this has been achieved is significantly smaller than a grain of sand, but still consists of several hundred million atoms. In contrast to ...

DURHAM, N.C. -- You dash into a convenience store for a quick snack, spot an apple and reach for a candy bar instead. Poor self-control may not be the only factor behind your choice, new research suggests. That's because our brains process taste information first, before factoring in health information, according to new research from Duke University. "We spend billions of dollars every year on diet products, yet most people fail when they attempt to diet," said study co-author Scott Huettel, a professor of psychology and neuroscience at Duke. "Taste seems to have an advantage that sets us up for failure." "For many individuals, health information enters the decision process ...

Injecting sulphur into the stratosphere to reduce solar radiation and stop the Greenland ice cap from melting. An interesting scenario, but not without risks. Climatologists from the University of Liège have looked into the matter and have tested one of the scenarios put forward using the MAR climate model developed at the University of Liège. The results are mixed and have been published in the journal The Cryosphere. The Greenland ice sheet will lose mass at an accelerated rate throughout the 21st century, with a direct link between anthropogenic greenhouse gas emissions and the extent of Greenland's mass loss. To combat this phenomenon, and therefore global warming, it is essential to reduce ...

ITHACA, N.Y. - An interdisciplinary team of Cornell and Harvard University researchers developed a machine learning tool to parse quantum matter and make crucial distinctions in the data, an approach that will help scientists unravel the most confounding phenomena in the subatomic realm. The Cornell-led project's paper, "Correlator Convolutional Neural Networks as an Interpretable Architecture for Image-like Quantum Matter Data," published June 23 in Nature Communications. The lead author is doctoral student Cole Miles. The Cornell team was led by Eun-Ah Kim, professor of physics in the College of Arts and Sciences, who partnered with Kilian Weinberger, associate professor of computing and information science in the Cornell Ann S. ...

When you insist you're not racist, you may unwittingly be sending the opposite message. That's the conclusion of a new study* by three Berkeley Haas researchers who conducted experiments with white participants claiming to hold egalitarian views. After asking them to write statements explaining why they weren't prejudiced against Black people, they found that other white people could nevertheless gauge the writers' underlying prejudice. "Americans almost universally espouse egalitarianism and wish to see themselves as non-biased, yet racial prejudice persists," says Berkeley ...

A genetic map of an aggressive childhood brain tumour called medulloblastoma has helped researchers identify a new generation anti-cancer drug that can be repurposed as an effective treatment for the disease. This international collaboration, led by researchers from The University of Queensland's (UQ) Diamantina Institute and WEHI in Melbourne, could give parents hope in the fight against the most common and fatal brain cancer in children. UQ lead researcher Dr Laura Genovesi said the team had mapped the genetics of these aggressive brain tumours for five years to find new pathways that existing drugs could potentially target. "These are drugs already approved for other diseases or cancers but have never been tested in paediatric brain tumours," Dr Genovesi ...