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Cell structure discovery advances understanding of cancer development

Cell structure discovery advances understanding of cancer development
2015-07-10
University of Warwick researchers have discovered a cell structure which could help scientists understand why some cancers develop. For the first time a structure called 'the mesh' has been identified which helps to hold together cells. This discovery, which has been published in the online journal eLife, changes our understanding of the cell's internal scaffolding. This also has implications for researchers' understanding of cancer cells as the mesh is partly made of a protein which is found to change in certain cancers, such as those of the breast and bladder. The ...

Obesity drug has no effect on baby birthweights, study finds

2015-07-10
Treating obese pregnant women with a diabetes drug does not stop their babies from being born overweight, a study has found. Doctors had hoped that the treatment would help to reduce obesity rates and lower the number of difficult births. Heavier babies are more likely to grow into overweight adults. They also have a higher risk of illnesses later in life, such as diabetes and heart disease. It is thought that the additional weight gain in the womb is caused by exposure to excess blood sugar. Researchers tested whether treating overweight mothers-to-be with the ...

Tunneling out of the surface

Tunneling out of the surface
2015-07-10
A research team comprising scientists from Tohoku University, RIKEN, the University of Tokyo, Chiba University and University College London have discovered a new chemical reaction pathway on titanium dioxide (TiO2), an important photocatalytic material. The reaction mechanism, reported in ACS Nano, involves the application of an electric field that narrows the width of the reaction barrier, thereby allowing hydrogen atoms to tunnel away from the surface. This opens the way for the manipulation of the atomic-scale transport channels of hydrogen, which could be important ...

A jump for soft-bodied robots

2015-07-10
(BOSTON) - Traditional robots are made of components and rigid materials like you might see on an automotive assembly line - metal and hydraulic parts, harshly rigid, and extremely strong. But away from the assembly line, for robots to harmoniously assist humans in close-range tasks scientists are designing new classes of soft-bodied robots. Yet one of the challenges is integrating soft materials with requisite rigid components that power and control the robot's body. At the interface of these materials, stresses concentrate and structural integrity can be compromised, ...

Ancestral diets determine vulnerability to type 2 diabetes

2015-07-10
The middle classes from developing countries are more susceptible than western Caucasians to obesity, type 2 diabetes and cardiovascular disease in today's changing environment. New research published today in Cell Metabolism from the University of Sydney in Australia, the National Centre for Cell Science and the DYP Medical College in Pune, India reveals this may be a result of the nutrition endured by their ancestors. The findings in the paper titled Multigenerational Undernutrition and Diabetes could explain projections that more than 70 per cent of the global burden ...

Surgery may be best treatment option for multidirectional shoulder dislocations

2015-07-10
ORLANDO, FL - While multidirectional instability of the shoulder (MDI) has been traditionally treated without surgery, research presented today at the American Orthopaedic Society for Sports Medicine's (AOSSM) Annual Meeting in Orlando, FL, shows surgery is also effective for this type of dislocation. "We examined 41 athletes who received arthroscopic surgery for MDI, and noted 73% returned to play at equal or only slightly lower level than before the injury," commented M. Brett Raynor, MD, lead author from Steadman Philippon Research Institute Program. "Our study group ...

Treatment of shoulder instability helps return collegiate athletes to playing field

2015-07-10
ORLANDO, FL - Athletes who suffer a shoulder instability injury may return to play more successfully after being treated arthroscopically compared to nonoperative treatment, say researchers presenting their work today at the American Orthopaedic Society for Sports Medicine's (AOSSM) Annual Meeting. "Our research highlights that collegiate collision athletes with in-season shoulder instability injuries are more likely to return to sport successfully the following season, if they undergo arthroscopic stabilization compared to nonoperative treatment," said lead author Jon ...

No need to treat stable meniscus tears during ACL surgery, new research shows

2015-07-10
ORLANDO, FL - While athletes undergoing anterior cruciate ligament (ACL) surgery often have an additional meniscus injury, treating these tears at the same time may not be necessary. Research presented today by the MOON Knee Group at the American Orthopaedic Society for Sports Medicine's (AOSSM) Annual Meeting in Orlando shows positive results for meniscal tears that were deemed stable and left alone at the time of ACL reconstruction. "We examined 194 patients with meniscus tears who did not receive treatment at the time of ACL surgery," noted lead author Kyle R. Duchman, ...

Risk of COPD may already occur in adolescence

2015-07-10
Chronic obstructive pulmonary disease (COPD) is one of most common causes of death in the world today - active smoking accounting for approx. 85% of all cases. Yet ground-breaking research from the University of Copenhagen indicates that accelerated decline of lung function is not a prerequisite for COPD. It has been generally assumed that all people suffering COPD experience an accelerated decline of lung function, which is why so many large studies have focused on reducing this decline. However, this new study reveals that this is the case for only approx. 50% of patients ...

'Jumping genes' may drive esophageal cancer

2015-07-10
CANCER RESEARCH UK scientists have found that 'jumping genes' may add to the genetic chaos behind more than three-quarters of oesophageal cancer cases, according to research* published in BMC Genomics today (Friday). The scientists, from the University of Cambridge, used cutting-edge technology that can read DNA to study the genes of 43 oesophageal tumour and blood samples to discover how much these mobile genetic sequences travel. 'Jumping genes', called L1 elements, can uproot themselves and move to new areas in the DNA, sometimes accidentally moving into genes that ...

Less intensive chemo avoids irreversible side effects in children's cancer

2015-07-10
CHILDREN with a rare type of cancer called Wilms' tumour who are at low risk of relapsing can now be given less intensive treatment, avoiding a type of chemotherapy that can cause irreversible heart problems in later life. The move follows the results of a Cancer Research UK trial, published in the Lancet* today (Thursday), showing that the drug doxorubicin can be safely omitted from treatment without affecting patients' chances of survival. Wilms' tumour is a type of kidney cancer that affects around 80 children a year in the UK, most under the age of seven. Until now, ...

Strong family bonds reduce anxiety in young people with lived experience of domestic violence

2015-07-10
Strong relationships with other family members can help raise self-esteem and reduce anxiety for some young people who grow up in homes affected by parental domestic violence. This is the finding of a study by Doctoral student Catherine Naughton and colleagues from the University of Limerick that will be presented today, Friday 10 July 2015, at the British Psychological Society's Psychology of Women Section's annual conference being held in Windsor. Catherine Naughton said: "Research has previously shown that strong social bonds can act as a beneficial psychological ...

Diet and exercise does not prevent gestational diabetes in obese women

2015-07-10
A diet and exercise regime for high-risk obese pregnant women, whilst effective in promoting a healthy lifestyle, does not prevent gestational diabetes, finds a study led by King's College London. The findings, published in the Lancet Diabetes and Endocrinology, suggest that programmes promoting healthy behaviours are unlikely to be effective in preventing diabetes in obese women; instead, resources should be directed towards better screening and treatment, including the use of a more stringent threshold for diagnosis. Obesity rates are highest in developed countries, ...

ECG scans predict kidney disease patients' risk of dying from heart disease

2015-07-10
Highlight Certain electrocardiogram measures helped investigators identify a subgroup of individuals with chronic kidney disease who had substantially elevated risks of dying from heart disease. An estimated 26 million people in the United States have chronic kidney disease, and heart disease is the leading cause of death in these patients. Washington, DC (July 9, 2015) -- Several common measures obtained from electrocardiograms (ECGs) may help clinicians determine a kidney disease patient's risk of dying from heart disease. The findings, which are published in a study ...

Uric acid may lessen women's disability after stroke

2015-07-09
DALLAS, July 9, 2015 -- Uric acid - a chemical at high levels can lead to serious illness - may lessen women's disability after stroke, according to new research in the American Heart Association's journal Stroke. High levels of uric acid can lead to kidney stones or the inflammatory arthritic condition known as gout and is linked with heart and vascular problems and diabetes. However, in a new study, 42 percent of women treated with uric acid therapy following a stroke had little to no disability after 90 days compared to 29 percent of women treated with a placebo. Women ...

Evidence from past suggests climate trends could yield 20-foot sea-level rise

2015-07-09
When past temperatures were similar to or slightly higher than the present global average, sea levels rose at least 20 feet, suggesting a similar outcome could be in store if current climate trends continue. Findings published in the journal Science showed that the seas rose in response to melting ice sheets in Greenland and Antarctica, said lead author Andrea Dutton, a University of Florida geochemist. "This evidence leads us to conclude that the polar ice sheets are out of equilibrium with the present climate," she said. Dutton and an international team of scientists ...

Nutrition researchers develop the healthy beverage index

2015-07-09
Philadelphia, PA, July 9, 2015 - Researchers at Virginia Tech have developed a new scoring method for assessing beverage intake, the Healthy Beverage Index (HBI). In a report published in the Journal of the Academy of Nutrition and Dietetics they describe how this tool can be used to more accurately evaluate dietary consumption of all types of fluids. They found that higher HBI scores were associated with more favorable lipid profiles, decreased risk of hypertension; and, among men, better C-reactive protein (CRP) levels. Water consumption is associated with numerous ...

Everyday access to nature improves quality of life in older adults

2015-07-09
Natural environments are known to promote physical, mental, and spiritual healing. People can attain health benefits by spending time outside, often in remote places to "get away from it all." Now research conducted by a University of Minnesota graduate student with a team in Vancouver, B.C., shows that green and "blue" spaces (environments with running or still water) are especially beneficial for healthy aging in seniors. Published in the journal Health and Place, the study -Therapeutic landscapes and wellbeing in later life: Impacts of blue and green spaces for older ...

Scientists study atmosphere of Venus through transit images

Scientists study atmosphere of Venus through transit images
2015-07-09
Two of NASA's heliophysics missions can now claim planetary science on their list of scientific findings. A group of scientists used the Venus transit - a very rare event where a planet passes between Earth and the sun, appearing to us as a dark dot steadily making its way across the sun's bright face - to make measurements of how the Venusian atmosphere absorbs different kinds of light. This, in turn, gives scientists clues to exactly what elements are layered above Venus's surface. Gathering such information not only teaches us more about this planet so close to our own, ...

NASA's Aqua satellite observes Supertyphoon Nangka

NASAs Aqua satellite observes Supertyphoon Nangka
2015-07-09
NASA's Aqua satellite passed over Supertyphoon Nangka on July 9 and provided a visible and an infrared view of the large storm. At 0700 UTC (3 a.m. EDT) on July 9 a typhoon warning was in effect for Agrihan, Pagan and Alamagan in the northern Marianas. A tropical storm warning is in effect for Saipan and Tinian. Nangka passed over Alamagan. The Atmospheric Infrared Sounder or AIRS instrument aboard NASA's Aqua satellite gathered infrared temperature data on Nangka on July 9 at 03:23 UTC (July 8 at 11:23 a.m. EDT). At the same time, the MODIS instrument took a visible ...

New genomic analysis identifies recurrent fusion genes in gastric cancers

2015-07-09
Studying the gastric cancers of 15 Southeast Asian patients, researchers at The Jackson Laboratory, the Genome Institute of Singapore and other institutions identified five recurrent fusion genes, one of which appears to lead to cellular changes involved in acute gastritis and cancer. Worldwide, close to a million cases of gastric cancers are diagnosed each year, and some of the world's highest incidence rates are in Asia (particularly in Korea, Japan and China). The researchers, led by JAX Professor Yijun Ruan, Ph.D., and Axel M. Hillmer, Ph.D., of GIS, published ...

Researchers identify critical genes responsible for brain tumor growth

2015-07-09
LOS ANGELES (July 9, 2015) - After generating new brain tumor models, Cedars-Sinai scientists in the Board of Governors Regenerative Medicine Institute identified the role of a family of genes underlying tumor growth in a wide spectrum of high grade brain tumors. "With these new genetic findings, our group of researchers plan to develop targeted therapeutics that we hope will one day be used treat patients with high grade brain tumors and increase their survival," said Joshua Breunig, PhD, a research scientist in the Brain Program at the Cedars-Sinai Board of Governors ...

Tropical Storm Ela becomes the Central Pacific's first named storm

Tropical Storm Ela becomes the Central Pacifics first named storm
2015-07-09
Tropical Storm Ela was born in the western-most part of the Eastern Pacific Ocean but has become the Central Pacific's first named storm. NASA's Aqua satellite took a look at the storm that's already battling wind shear to survive. After developing as a depression on July 8, Tropical Depression 4E crossed over the 140 degree West longitude line that separates the Eastern Pacific from the Central Pacific Ocean region. The depression strengthened into a tropical storm early on July 9, taking a name from the Eastern Pacific tropical cyclone list and being renamed Ela. When ...

Spinal cord injuries increasing, especially among older individuals

2015-07-09
Traumatic spinal cord injuries are increasing with the population, and incidence is higher in older individuals, according to a Vanderbilt study that was published in the June 9 issue of the Journal of the American Medical Association. The study, which analyzed data from 63,109 patients with acute traumatic spinal cord injury from 1993 to 2012, will help target specific populations for preventive measures, said lead author Nitin B. Jain, M.D., M.S.P.H, associate professor of Physical Medicine and Rehabilitation. "We find that spinal cord injury as a result of falls is ...

Tropical peatland carbon losses from oil palm plantations may be underestimated

2015-07-09
MINNEAPOLIS / ST. PAUL (7/9/2015) -- Draining tropical peatlands for oil palm plantations may result in nearly twice as much carbon loss as official estimates, according to a new study by researchers from the University of Minnesota Institute on the Environment and the Union of Concerned Scientists in the journal Environmental Research Letters. Peatlands -- waterlogged, organic soils -- have developed over thousands of years as carbon storage systems. In Southeast Asia, peat swamp forests cover about 250,000 square kilometers, a land area about the size of Michigan. In ...
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