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Stanford researchers create 'evolved' protein that may stop cancer from spreading

Stanford researchers create evolved protein that may stop cancer from spreading
2014-09-21
VIDEO: Early but promising tests in lab mice suggest that a bioengineered 'decoy' protein, administered intravenously, can halt the spread of cancer from the original tumor site. Years of subsequent tests... Click here for more information. A team of Stanford researchers has developed a protein therapy that disrupts the process that causes cancer cells to break away from original tumor sites, travel through the blood stream and start aggressive new growths elsewhere in the body. This ...

Smallest possible diamonds form ultra-thin nanothreads

Smallest possible diamonds form ultra-thin nanothreads
2014-09-21
VIDEO: For the first time, scientists have discovered how to produce ultra-thin 'diamond nanothreads' that promise extraordinary properties, including strength and stiffness greater than that of today's strongest nanotubes and polymers.... Click here for more information. For the first time, scientists have discovered how to produce ultra-thin "diamond nanothreads" that promise extraordinary properties, including strength and stiffness greater than that of today's strongest ...

New cancer drug target involving lipid chemical messengers

New cancer drug target involving lipid chemical messengers
2014-09-19
PHILADELPHIA — More than half of human cancers have abnormally upregulated chemical signals related to lipid metabolism, yet how these signals are controlled during tumor formation is not fully understood. Youhai Chen, PhD, MD, and Svetlana Fayngerts, PhD, both researchers in the department of Pathology and Laboratory Medicine at the Perelman School of Medicine, University of Pennsylvania, and colleagues report that TIPE3, a newly described oncogenic protein, promotes cancer by targeting these pathways. Lipid second messengers play cardinal roles in relaying and amplifying ...

Melanoma risk found to have genetic determinant

2014-09-19
(Lebanon, NH 9/18/14)— A leading Dartmouth researcher, working with The Melanoma Genetics Consortium, GenoMEL, an international research consortium, co-authored a paper published today in the Journal of the National Cancer Institute that proves longer telomeres increase the risk of melanoma. "For the first time, we have established that the genes controlling the length of these telomeres play a part in the risk of developing melanoma," said lead author of the study Mark Iles, PhD, School of Medicine at the University of Leeds (UK). Telomeres are a part of the genome ...

UChicago-Argonne National Lab team improves solar-cell efficiency

UChicago-Argonne National Lab team improves solar-cell efficiency
2014-09-19
New light has been shed on solar power generation using devices made with polymers, thanks to a collaboration between scientists in the University of Chicago's chemistry department, the Institute for Molecular Engineering, and Argonne National Laboratory. Researchers identified a new polymer — a type of large molecule that forms plastics and other familiar materials — which improved the efficiency of solar cells. The group also determined the method by which the polymer improved the cells' efficiency. The polymer allowed electrical charges to move more easily throughout ...

Research predicts possible 6,800 new Ebola cases this month

2014-09-19
Tempe, Ariz. (Sept. 19, 2014) - New research published today in the online journal PLoS Outbreaks predicts new Ebola cases could reach 6,800 in West Africa by the end of the month if new control measures are not enacted. Arizona State University and Harvard University researchers also discovered through modelling analysis that the rate of rise in cases significantly increased in August in Liberia and Guinea, around the time that a mass quarantine was put in place, indicating that the mass quarantine efforts may have made the outbreak worse than it would have been otherwise. ...

Domestic violence likely more frequent for same-sex couples

2014-09-19
CHICAGO --- Domestic violence occurs at least as frequently, and likely even more so, between same-sex couples compared to opposite-sex couples, according to a review of literature by Northwestern Medicine scientists. Previous studies, when analyzed together, indicate that domestic violence affects 25 percent to 75 percent of lesbian, gay and bisexual individuals. However, a lack of representative data and underreporting of abuse paints an incomplete picture of the true landscape, suggesting even higher rates. An estimated one in four heterosexual women experience domestic ...

A better way to track emerging cell therapies using MRIs

2014-09-19
Cellular therapeutics – using intact cells to treat and cure disease – is a hugely promising new approach in medicine but it is hindered by the inability of doctors and scientists to effectively track the movements, destination and persistence of these cells in patients without resorting to invasive procedures, like tissue sampling. In a paper published September 17 in the online journal Magnetic Resonance in Medicine, researchers at the University of California, San Diego School of Medicine, University of Pittsburgh and elsewhere describe the first human tests of using ...

NASA catches a weaker Edouard, headed toward Azores

NASA catches a weaker Edouard, headed toward Azores
2014-09-19
NASA's Aqua satellite passed over the Atlantic Ocean and captured a picture of Tropical Storm Edouard as it continues to weaken. The National Hurricane Center expects Edouard to affect the western Azores over the next two days. NASA's Aqua satellite flew over Tropical Storm Edouard on Sept. 18 at 1:45 p.m. EDT and the Moderate Resolution Imaging Spectroradiometer (MODIS) instrument took a visible picture that showed the eye had disappeared and the bulk of clouds pushed east of center. At 5 a.m. EDT on Sept. 19, Edouard's maximum sustained winds had decreased to near ...

NASA, NOAA satellites show Odile's remnant romp through southern US

NASA, NOAA satellites show Odiles remnant romp through southern US
2014-09-19
Former Hurricane Odile may be a bad memory for Baja California, but the remnants have moved over New Mexico and Texas where they are expected to bring rainfall there. NASA's TRMM satellite measured Odile's heavy rainfall rates on Sept. 18, and NOAA's GOES-West satellite saw the clouds associated with the former storm continue to linger over the U.S. Southwest on Sept. 19. The remnants of Hurricane Odile were dropping heavy rain in the area from southern Arizona to western Texas when NASA-JAXA's Tropical Rainfall Measuring Mission or TRMM satellite flew over on September ...

NASA sees Tropical Storm playing polo with western Mexico

NASA sees Tropical Storm playing polo with western Mexico
2014-09-19
Tropical Storm Polo is riding along the coast of western Mexico like horses in the game of his namesake. NASA's Aqua satellite saw Polo about 300 miles south-southeast of Baja California on its track north. NASA's Aqua satellite flew over Polo on Sept. 18 at 4:35 p.m. EDT and the Moderate Resolution Imaging Spectroradiometer captured a visible image of the storm that showed that much of the clouds, thunderstorms and showers were west and south of the center of circulation, and away from the coast. That's an indication that easterly wind shear had increased and were pushing ...

NASA eyes Tropical Storm Fung-Wong move through Northwestern Pacific

NASA eyes Tropical Storm Fung-Wong move through Northwestern Pacific
2014-09-19
Tropical Storm Fung-Wong continued to affect the Philippines while moving north through the Northwestern Pacific Ocean. NASA's Aqua satellite provided infrared data on the storm's clouds that showed some high, strong thunderstorms with the potential for heavy rainfall over the northern and central regions of the country. The storm is now expected to affect three more countries over the next several days. The AIRS instrument aboard NASA's Aqua satellite uses infrared light to read cloud top temperatures in tropical cyclones. When Aqua passed over Fung-Wong infrared data ...

Dwindling wind may tip predator-prey balance

Dwindling wind may tip predator-prey balance
2014-09-19
MADISON, Wis. — Bent and tossed by the wind, a field of soybean plants presents a challenge for an Asian lady beetle on the hunt for aphids. But what if the air — and the soybeans — were still? Rising temperatures and shifting precipitation patterns may get the lion's share of our climate change attention, but predators may want to give some thought to wind, according to a University of Wisconsin Madison zoologist's study, which is among the first to demonstrate the way "global stilling" may alter predator-prey relationships. "There are all sorts of other things that ...

A two generation lens: Current state policies fail to support families with young children

2014-09-19
September 19, 2014 -- Recent two-generation approaches to reducing poverty that help children and their parents are receiving increasing attention from researchers, advocates, and foundations. By combining education and training for parents to enable them to move to jobs that offer a path out of poverty with high-quality early care and education for children, these programs aim to improve the life opportunities of both. However, according to a new report from the National Center for Children in Poverty (NCCP), State Policies through a Two-Generation Lens, while research ...

Soft robotics 'toolkit' features everything a robot-maker needs

Soft robotics toolkit features everything a robot-maker needs
2014-09-19
A new resource unveiled today by researchers from several Harvard University labs in collaboration with Trinity College Dublin provides both experienced and aspiring researchers with the intellectual raw materials needed to design, build, and operate robots made from soft, flexible materials. With the advent of low-cost 3D printing, laser cutters, and other advances in manufacturing technology, soft robotics is emerging as an increasingly important field. Using principles drawn from conventional rigid robot design, but working with pliable materials, engineers are pioneering ...

Fingertip sensor gives robot unprecedented dexterity

2014-09-19
CAMBRIDGE, Mass-- Researchers at MIT and Northeastern University have equipped a robot with a novel tactile sensor that lets it grasp a USB cable draped freely over a hook and insert it into a USB port. The sensor is an adaptation of a technology called GelSight, which was developed by the lab of Edward Adelson, the John and Dorothy Wilson Professor of Vision Science at MIT, and first described in 2009. The new sensor isn't as sensitive as the original GelSight sensor, which could resolve details on the micrometer scale. But it's smaller — small enough to fit on a robot's ...

Mayo researchers reveal pathway that contributes to Alzheimer's disease

2014-09-19
JACKSONVILLE, Fla. — Researchers at Jacksonville's campus of Mayo Clinic have discovered a defect in a key cell-signaling pathway they say contributes to both overproduction of toxic protein in the brains of Alzheimer's disease patients as well as loss of communication between neurons — both significant contributors to this type of dementia. Their study, in the online issue of Neuron, offers the potential that targeting this specific defect with drugs "may rejuvenate or rescue this pathway," says the study's lead investigator, Guojun Bu, Ph.D., a neuroscientist at Mayo ...

A refined approach to proteins at low resolution

A refined approach to proteins at low resolution
2014-09-19
Membrane proteins and large protein complexes are notoriously difficult to study with X-ray crystallography, not least because they are often very difficult, if not impossible, to crystallize, but also because their very nature means they are highly flexible. The result is that when a structure can be obtained it is often of low resolution, ambiguous and reveals a mosaic-like spread of protein domains that sometimes create more puzzles than they solve. [Schröder, Levitt & Brunger. (2014), Acta Cryst. D70, 2241-2255; doi: 10.1107/S1399004714016496 ] Now, Gunnar Schröder ...

Reflected smartphone transmissions enable gesture control

Reflected smartphone transmissions enable gesture control
2014-09-19
With almost all of the U.S. population armed with cellphones – and close to 80 percent carrying a smartphone – mobile phones have become second-nature for most people. What's coming next, say University of Washington researchers, is the ability to interact with our devices not just with touchscreens, but through gestures in the space around the phone. Some smartphones are starting to incorporate 3-D gesture sensing based on cameras, for example, but cameras consume significant battery power and require a clear view of the user's hands. UW engineers have developed a ...

Patients with advanced, incurable cancer denied palliative care

2014-09-19
Many patients with advanced, incurable cancer do not receive any palliative care, reveals new research to be presented later this month at the ESMO 2014 Congress in Madrid, Spain, 26-30 September. The findings are astonishing as they come at the same time as 15 new oncology centres in Europe, Canada, South America and Africa are being awarded the prestigious title of 'ESMO Designated Centre of Integrated Oncology and Palliative Care.' SR I Dr Alexandru Grigorescu, medical oncology consultant at the Institute of Oncology Bucharest, Romania, member of the ESMO Palliative ...

Graphene sensor tracks down cancer biomarkers

Graphene sensor tracks down cancer biomarkers
2014-09-19
An ultrasensitive biosensor made from the wonder material graphene has been used to detect molecules that indicate an increased risk of developing cancer. The biosensor has been shown to be more than five times more sensitive than bioassay tests currently in use, and was able to provide results in a matter of minutes, opening up the possibility of a rapid, point-of-care diagnostic tool for patients. The biosensor has been presented today, 19 September, in IOP Publishing's journal 2D Materials. To develop a viable bionsensor, the researchers, from the University of ...

Simple test can help detect Alzheimer's before dementia signs show: York U study

2014-09-19
TORONTO, Sept. 19, 2014 — York University researchers say a simple test that combines thinking and movement can help to detect heightened risk for developing Alzheimer's disease in a person, even before there are any telltale behavioural signs of dementia. Faculty of Health Professor Lauren Sergio and PhD candidate Kara Hawkins who led the study asked the participants to complete four increasingly demanding visual-spatial and cognitive-motor tasks, on dual screen laptop computers. The test aimed at detecting the tendency for Alzheimer's in those who were having cognitive ...

Shrink-wrapping spacesuits

2014-09-19
For future astronauts, the process of suiting up may go something like this: Instead of climbing into a conventional, bulky, gas-pressurized suit, an astronaut may don a lightweight, stretchy garment, lined with tiny, musclelike coils. She would then plug in to a spacecraft's power supply, triggering the coils to contract and essentially shrink-wrap the garment around her body. The skintight, pressurized suit would not only support the astronaut, but would give her much more freedom to move during planetary exploration. To take the suit off, she would only have to apply ...

New hadrosaur noses into spotlight

New hadrosaur noses into spotlight
2014-09-19
Call it the Jimmy Durante of dinosaurs – a newly discovered hadrosaur with a truly distinctive nasal profile. The new dinosaur, named Rhinorex condrupus by paleontologists from North Carolina State University and Brigham Young University, lived in what is now Utah approximately 75 million years ago during the Late Cretaceous period. Rhinorex, which translates roughly into "King Nose," was a plant-eater and a close relative of other Cretaceous hadrosaurs like Parasaurolophus and Edmontosaurus. Hadrosaurs are usually identified by bony crests that extended from the skull, ...

Researchers discover new gene responsible for traits involved in diabetes

2014-09-19
A collaborative research team led by Medical College of Wisconsin (MCW) scientists has identified a new gene associated with fasting glucose and insulin levels in rats, mice and in humans. The findings are published in the September issue of Genetics. Leah Solberg Woods, Ph.D., associate professor of pediatrics at MCW and a researcher in the Children's Hospital of Wisconsin Research Institute, led the study and is the corresponding author of the paper. The authors of the paper identified a gene called Tpcn2 in which a variant was associated with fasting glucose levels ...
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