City of Hope-led study demystifies tumor formation’s two-step process — a foundational understanding needed to prevent cancer
LOS ANGELES — Researchers at City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, have found that cell mutations are necessary but not always sufficient for tumors to form. Instead, they suggest that additional risk factors that promote tumor growth, like chronic inflammation, are a key trigger for tumor formation.
The study findings, published this month in Cancer Discovery, answer a question that scientists have long asked: Are cell mutations alone ...












