BOSTON – The discovery that a protein called Rictor plays a key role in destroying a close cousin of the AKT oncogene could provide scientists with a new molecular target for treating certain cancers, including breast cancer. Described in the September 2010 issue of the journal Molecular Cell, the study was led by scientists at Beth Israel Deaconess Medical Center (BIDMC). The oncogenic cousin, known as SGK1, resembles the widely known AKT oncogene in structure, according to the study's senior author Wenyi Wei, PhD, of the Department of Pathology at BIDMC and Assistant ...

LIVERMORE, Calif. – Beta cells, which make insulin in the human body, do not replicate after the age of 30, indicating that clinicians may be closer to better treating diabetes. Type 1 diabetes is caused by a loss of beta cells by auto-immunity while type 2 is due to a relative insufficiency of beta cells. Whether beta cells replicate after birth has remained an open issue, and is critically important for designing therapies for diabetes. By using radioactive carbon-14 produced by above-ground nuclear testing in the 1950s and '60s, researchers have determined that the ...

Noble metals such as platinum and palladium are becoming increasingly important because of growth in environmentally friendly applications such as fuel cells and pollution control catalysts. But the world has limited quantities of these materials, meaning manufacturers will have to rely on efficient recycling processes to help meet the demand. Existing recycling processes use a combination of two inorganic acids known as "aqua regia" to dissolve noble metals, a class of materials that includes platinum, palladium, gold and silver. But because the metals are often dissolved ...

Montreal, October 28, 2010 – A team of scientists at the Institut de recherches cliniques de Montréal (IRCM) led by Dr. Jean-François Côté, Director of the Cytoskeletal Organization and Cell Migration research unit, identified a novel molecular mechanism in the control of cell motility. Their findings were published online today in Current Biology, a journal from the Cell Press group. This scientific breakthrough could eventually lead to the development of new cancer-treating drugs that could block the spread of tumours (metastasis). "As many as 90% of cancer patient ...

Two spacecraft are now beginning to study the moon's environment as part of NASA's ARTEMIS mission, whose principal investigator is Vassilis Angelopoulos, a UCLA professor of Earth and space sciences. One of these satellites has been in the lunar environment since Aug. 25, and the second arrived Oct. 22, marking the start of the ARTEMIS mission to gather new scientific data in the sun-Earth-moon environment. ARTEMIS is an acronym for Acceleration, Reconnection, Turbulence and Electrodynamics of the Moon's Interaction with the Sun. For roughly six months, the ...

URBANA – Finding good child care and being able to engage easily in important interactions with your child care provider are critical to any mother's ability to work outside the home. "Suppose you're living in the rural Midwest and you don't speak English very well. Can you imagine leaving your child with a child care provider if you couldn't communicate well with that person?" said Angela Wiley, a University of Illinois associate professor of applied family studies. "The immigrant moms we interviewed for this study faced just this dilemma," she said. Immigrant Latino ...

Researchers from Mount Sinai School of Medicine have identified a mechanism controlling the function of a protein that binds to DNA during embryonic development and may function to prevent abnormal tumor growth. When the protein, TCF3, is modified by a small molecule called a phosphate, it no longer binds DNA, changing the way the protein signals during development. This discovery identifies a new diagnostic marker (phosphorylated TCF3) that may be associated with cancer and could represent a potential drug target. The results are published in the current issue of Developmental ...

CORAL GABLES, FL (October 28, 2010)—To help unravel the mysteries of human cognitive development and reach new the frontiers in robotics, University of Miami (UM) developmental psychologists and computer scientists from the University of California in San Diego (UC San Diego) are studying infant-mother interactions and working to implement their findings in a baby robot capable of learning social skills. The first phase of the project was studying face-to-face interactions between mother and child, to learn how predictable early communication is, and to understand what ...

Strong immunity may play a key role in determining long life, but may do so at the expense of reduced fertility, a Princeton University study has concluded. An 11-year study of a population of wild sheep located on a remote island off the coast of Scotland that gauged the animals' susceptibility to infection may give new insight into why some people get sicker than others when exposed to the same illness. The answer to this medical puzzle may lie in deep-rooted differences in how animals survive and reproduce in the wild, according to the study, which was led by Princeton ...

A University of Alberta geomicrobiologist and his PhD student are part of a research team that has identified phosphorus as the mystery ingredient that pushed oxygen levels in the oceans high enough to establish the first animals on Earth 750 million years ago. By examining ancient-ocean sediments, Kurt Konhauser, student Stefan Lalonde and other colleagues discovered that as the last glacier to encircle Earth receded, leaving behind glacial debris containing phosphorus that washed into the oceans. Phosphorus is an essential nutrient that promoted the growth of cyanobacteria, ...

AURORA, Colo. (Oct. 28, 2010) - A study in the New England Journal of Medicine shows more than half of patients with a specific kind of lung cancer are responding positively to a treatment that targets the gene that drives their cancer. The study shows 57 percent of patients with ALK-positive advanced non-small cell lung cancer responded partially or completely to a tablet called crizotinib, an investigational anaplastic lymphoma kinase (ALK) inhibitor. In some cases, the cancer becomes undetectable in body scans. The data is published in the October 28 issue of the ...

DURHAM, N.H. – A major new study that sounds a conservation alarm for the world's vertebrate species notes that the world's seagrass species are faring somewhat better, says a University of New Hampshire researcher who was a coauthor of the study. Fred Short, UNH research professor of natural resources and director of the worldwide program SeagrassNet, was among the 174 scientists who contributed to "The Impact of Conservation on the Status of the World's Vertebrates," released online this week in the journal Science. "Some areas, including New Hampshire, are experiencing ...

NEW YORK (Oct. 28, 2010) -- Scientists at Weill Cornell Medical College have identified a potential new treatment for the Nipah and Hendra viruses, two lethal and emerging viruses for which there is currently no treatment or vaccine available. The approach could also lead to new therapies for measles, mumps and the flu. The new research appears in today's edition of the prestigious journal Public Library of Science (PLoS) Pathogens. The Nipah and Hendra viruses are members of the genus Henipavirus, a new class of virus in the Paramyxoviridae family, which includes the ...

Warm days are coming back in Canberra: time to head outside and make the most of what the Capital city has to offer, besides museums! For Canberrans, it's a great opportunity to come and enjoy their local playground with a twist: they are sure to discover some places through a different light, running, paddling and riding around with their team. For would-be participants who are not from the area, this is a chance to come down with colleagues, mates or family and make a weekend out of it. There are options for all, so bring the family and experience the great hands-on museums, ...

Finding an apartment in New York is possible. Just do your homework. We spoke with Alicia Schwartz; she's the director of the rental resource http://www.HowToRentInNYC.com. The following is her advice. Think about hiring a broker. If your time is limited or you've been looking but haven't found the apartment of your dreams, a broker could make the difference. They may end up showing you an apartment you could have found yourself. But keep in mind they can show you places you would never have had access to. But if the thought of paying one really puts you off; usually ...

Three artists, Gregg Stecker, Toby Thompson and Laura Eklund will show and discuss their work as well as the approach they take to conceive it - from graphic art to visionary. The show, "An Eclectic Approach," combines different styles of work - offering something for a variety of artistic tastes. "I wanted to put a show together that would cover a variety of preferences and tastes," say Gallery owner Lori Frary. "I believe we've achieved that with this group of artists. No matter what your preference, you won't be disappointed and you may discover something completely ...

The adorable characters that make child's dreams come true in their very own virtual life, inspires Cherokee uniforms manufacturer to continue creating Disney inspired scrub tops. And this time, female professional health care workers are the targeted customers, not the children anymore. By combining femininity with the cutest and most adorable cartoon characters, Cherokee uniforms remain as the most sought after when it comes to such designs. Even if it comes to print scrubs, other than tooniforms, Cherokee proved to be among the most searched for scrub tops. http://www.youtube.com/watch?v=7pF1BlGtLvc The ...

¡VIVA! MARKET within its 15,000-sqft building allows you to enjoy a nostalgic experience with sights, sounds, smells, and products of Latin America in an upscale grocery market. This market represents the first of its kind in the Ogden area meeting the needs of Ogden's 45% Latin-American population. In addition to the grocery portion of the store, the market will include: a Panadería, Tortillaría, Taquería, Carnicería, Mexican Restaurant, and numerous other vendors. Come join us for the Grand Opening of ¡VIVA! MARKET on Saturday October 30th between 11 AM and 6 PM where ...

It is time that there is an information network for people to be able to get everything they need to know in one spot, and not have to pay hundreds for a professional, or buy many different books to cover all the possible dog training and social behavior problems that affect dogs. A new blog dedicated to doing just that has been launched recently. Dan Bradie, an experienced dog psychologist, and co-founder of Apollo Inc says "People need the proper info and more importantly, the right info. You don't need a dog whisperer, YOU are the dog whisperer, you just don't know ...

"We're talking 'Welcome to a nightmare on Shepherd Drive,' complete with booty-bumpin' beats by me - a.k.a. DJ Wine-O - the best bites and cocktails in town, and a costume contest with very cool prizes," says Evan Turner, Branch Water Tavern's front of the house guy and beverage extraordinaire. "In the interest of preserving what will be a shocking, mind-bending, whiskey addled experience, we'll spare you most of the gory details," says Turner. For now, just know this: • Best costume will be awarded a private chef tasting for four by Executive Chef David Grossman ...

Macro Sensors provides instructions on how to connect, install and calibrate the EAZY-CAL MME-1000 mini-module, the world¡¦s most user-friendly LVDT signal conditioner, on http://www.youtube.com/user/MacroSensorsSales?feature=mhum.The YouTube video shows that a virtually effortless fingertip calibration routine can be used to field calibrate the EAZY-CAL signal conditioner in just mere seconds. The EAZY-CAL™ MME-1000 mini-module (http://www.macrosensors.com/MME-1000.html) saves time and money by eliminating repetitive null and span potentiometer adjustments ...

Dunn-Wright Remodeling President Jeff Stief recently attended the San Antonio "Live Green" Festival sponsored by the San Antonio Parks and Recreation Department and CPS at Olmos Park Basin, both as an attendee at the Dunn-Wright Remodeling display booth, http://www.dunn-wright.net, and as an observer of the recently renovated park and the features of other companies and their products. "I was really impressed with the improvements to the park" Stief said. "I used to live about five houses up the road from the baseball parks. That was almost 15 years ago. I would take ...

myBiodentity Corp a global innovator in biometrics enabled solutions has released a major update to bio-iVault Encrypted Virtual Drive Manager which uses the well respected myBiometrix Biometric platform to deliver Finger, Face and Voice verification to securely create and manage the encrypted virtual drives. Using Biometrics means No Passwords to remember or have stolen. The bio-iVault drives appear just like a normal drive in Explorer, so files can be created, edited and deleted just as is done on a normal drive. The important difference is the bio-iVault drive is ...

TugboatLife.com, an online maritime community with more than 3,000 members, is seeking applicants who are interested in participating in a tugboat-based reality television program. The proposed program is being developed by nationally recognized television producers with more than 20 years' experience in television production. "Tugboat Life is pleased to assist the producers in locating the best possible cast members for this show," says Judd Spence, who operates the Tugboat Life site. "There are few more interesting settings for a reality show than on a tugboat. It's ...

Akran Marketing Formally Registers Akran Foundation as a Community-Based, Non-Profit Organization Akran Marketing, recognized for being socially, ethically and environmentally responsible, and the country's leading branding, premium incentive and licensing company, today announced the establishment of the Akran Foundation, a community-based, non-profit organization. Raman Agarwal, President & CEO of Akran Marketing stated, "Philanthropy has been a significant component of our corporate culture at Akran. We have been contributing to numerous charities for the last ...