Suicide and self-harm events with GLP-1 receptor agonists in adults with diabetes or obesity

About The Study: There is unlikely to be an increase in the very low incidence of suicide-related adverse events among individuals receiving glucagon-like peptide 1 receptor agonists (GLP-1 RAs) within the context of randomized clinical trials. While these findings may further ease concerns about these adverse effects, continued monitoring is warranted to identify particular patients who may be at risk as extended use of GLP-1 RAs expands. 

Corresponding Author: To contact the corresponding author, Sean P. Heffron, MD, MS, MSc, email sean.heffron@nyulangone.org.

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(10.1001/jamapsychiatry.2025.0091)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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