Suicide and self-harm events with GLP-1 receptor agonists in adults with diabetes or obesity

JAMA Psychiatry

2025-03-19

(Press-News.org) About The Study: There is unlikely to be an increase in the very low incidence of suicide-related adverse events among individuals receiving glucagon-like peptide 1 receptor agonists (GLP-1 RAs) within the context of randomized clinical trials. While these findings may further ease concerns about these adverse effects, continued monitoring is warranted to identify particular patients who may be at risk as extended use of GLP-1 RAs expands.

Corresponding Author: To contact the corresponding author, Sean P. Heffron, MD, MS, MSc, email sean.heffron@nyulangone.org.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(10.1001/jamapsychiatry.2025.0091)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Suicide and self-harm events with GLP-1 receptor agonists in adults with diabetes or obesity

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