(Press-News.org) About The Study: Among patients without documented atrial arrhythmia recurrence after catheter ablation for atrial fibrillation, discontinuing oral anticoagulant therapy resulted in a lower risk for the composite outcome of stroke, systemic embolism, and major bleeding vs continuing direct oral anticoagulant therapy.
Corresponding Author: To contact the corresponding author, Boyoung Joung, MD, email cby6908@yuhs.ac.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2025.14679?guestAccessKey=3d97c611-aa9b-4680-b726-db495a67c47b&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=083125
END
Long-term anticoagulation discontinuation after catheter ablation for atrial fibrillation
JAMA
2025-08-31
ELSE PRESS RELEASES FROM THIS DATE:
Fractional flow reserve–guided complete vs culprit-only revascularization in non–ST-elevation myocardial infarction and multivessel disease
2025-08-31
About The Study: Fractional flow reserve-guided complete revascularization during the index procedure resulted in a significant reduction in the composite of all-cause death, nonfatal myocardial infarction, any revascularization, and stroke at 1 year. This was mainly driven by reduced repeat revascularization.
Corresponding Author: To contact the corresponding author, Tobias F. S. Pustjens, MD, email t.pustjens@gmail.com.
To access the embargoed study: Visit our For The Media website at this link ...
Participation of women in cardiovascular trials from 2017 to 2023
2025-08-31
About The Study: The findings of this study highlight both progress and persistent challenges in representation of women within cardiovascular trials. These gaps not only limit the generalizability of trial outcomes but also perpetuate inequities in evidence-based care for women with cardiovascular conditions.
Corresponding Author: To contact the corresponding author, Martha Gulati, MD, MS, email martha.gulati@csmc.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Editor’s Note: Please see the article for ...
Semaglutide and tirzepatide in patients with heart failure with preserved ejection fraction
2025-08-31
About The Study: In patients with cardiometabolic heart failure with preserved ejection fraction, semaglutide and tirzepatide showed more than 40% risk reduction for the composite of hospitalization for heart failure or all-cause mortality compared with a placebo proxy. Tirzepatide showed no meaningful benefit over semaglutide.
Corresponding Author: To contact the corresponding author, Nils Krüger, MD, email nkruger1@bwh.harvard.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Editor’s Note: Please ...
Changes in biology of internal fat may be the leading cause of heart failure
2025-08-31
Heart failure with preserved ejection fraction (HFpEF) appears to develop as a result of changes in the biology of a person’s internal fat tissue, according to the Adipokine Hypothesis, a new way of understanding how fat may impact the heart. The hypothesis paper was published today in JACC, the flagship journal of the American College of Cardiology, and is being presented at ESC Congress 2025. The author of the paper is Milton Packer, MD, FACC, Distinguished Scholar in Cardiovascular Science at Baylor University Medical Center at Dallas and Visiting Professor at Imperial College in London.
“Up ...
Transcatheter or surgical treatment of patients with aortic stenosis at low to intermediate risk
2025-08-30
About The Study: In this individual participant data meta-analysis of 4 randomized clinical trials (RCTs), and an overall meta-analysis of 8 RCTs of patients with severe symptomatic aortic stenosis at low to intermediate risk, transcatheter aortic valve implantation (TAVI) was associated with a reduction in the 1-year incidence of all-cause death or any stroke. These findings emphasize TAVI as alternative option in patients at low to intermediate risk. Long-term follow-up is warranted to evaluate sustainability of these findings.
Corresponding Authors: To contact the corresponding authors, email Moritz Seiffert, MD, (moritz.seiffert@bergmannsheil.de) and ...
Promising new drug for people with stubborn high blood pressure
2025-08-30
A new treatment has been shown to significantly lower blood pressure in people whose levels stay dangerously high, despite taking several existing medicines, according to the results of a Phase III clinical trial led by a UCL Professor.
Globally around 1.3 billion people have high blood pressure (hypertension), and in around half of cases the condition is uncontrolled or treatment resistant. These individuals face a much greater risk of heart attack, stroke, kidney disease, and early death. In the UK the number of people with hypertension is around 14 ...
One shot of RSV vaccine effective against hospitalization in older adults for two seasons
2025-08-30
One shot of an RSV vaccine protects adults ages 60 or older from RSV-associated hospitalization and critical illness during two consecutive RSV seasons, according to a study published in JAMA today by the IVY Network research group.
RSV causes substantial seasonal illness during fall and winter in the U.S., with an estimated 100,000-150,000 hospitalizations and 4,000-8,000 deaths occurring annually among adults 60 or older.
The results reinforce the recommendations for RSV vaccines in older adults and lay the groundwork for understanding how long a single dose of the vaccine may be effective, ...
Bivalent RSV prefusion F protein–based vaccine for preventing cardiovascular hospitalizations in older adults
2025-08-30
About The Study: In adults age 60 or older, all-cause cardiorespiratory hospitalization was significantly lower with respiratory syncytial virus (RSV) prefusion F protein than with no vaccine. The findings suggest potential downstream cardiorespiratory benefits of RSV immunization, although the effect on all-cause cardiovascular hospitalization was not statistically significant.
Corresponding Author: To contact the corresponding author, Tor Biering-Sørensen, MD, MSc, MPH, PhD, email tor.biering@gmail.com.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Editor’s ...
Clonal hematopoiesis and risk of new-onset myocarditis and pericarditis
2025-08-30
About The Study: In this study, clonal hematopoiesis of indeterminate potential (CHIP) was a strong risk factor for myocarditis and pericarditis among middle-aged adults. Targeting CHIP and its downstream pathways may represent a strategy for preventing or treating pericarditis and myocarditis.
Corresponding Author: To contact the corresponding author, Michael C. Honigberg, MD, MPP, email mhonigberg@mgh.harvard.edu.
To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/
Editor’s Note: Please see the article for additional information, including other authors, author contributions ...
Risk of myocarditis or pericarditis with high-dose vs standard-dose influenza vaccine
2025-08-30
About The Study: In this prespecified analysis of the DANFLU-2 trial, the risk of incident myocarditis or pericarditis was lower among individuals randomized to high-dose inactivated influenza vaccine vs standard-dose- inactivated influenza vaccine. Despite sporadic reports of myocarditis and pericarditis associated with influenza vaccination, the consistency of our results with vs without inclusion of events occurring immediately after vaccination negates a dose-response association and a causal link.
Corresponding Author: To ...
LAST 30 PRESS RELEASES:
Interaction of climate change and human activity and its impact on plant diversity in Qinghai-Tibet plateau
From addressing uncertainty to national strategy: an interpretation of Professor Lim Siong Guan’s views
Clinical trials on AI language model use in digestive healthcare
Scientists improve robotic visual–inertial trajectory localization accuracy using cross-modal interaction and selection techniques
Correlation between cancer cachexia and immune-related adverse events in HCC
Human adipose tissue: a new source for functional organoids
Metro lines double as freight highways during off-peak hours, Beijing study shows
Biomedical functions and applications of nanomaterials in tumor diagnosis and treatment: perspectives from ophthalmic oncology
3D imaging unveils how passivation improves perovskite solar cell performance
Enriching framework Al sites in 8-membered rings of Cu-SSZ-39 zeolite to enhance low-temperature ammonia selective catalytic reduction performance
AI-powered RNA drug development: a new frontier in therapeutics
Decoupling the HOR enhancement on PtRu: Dynamically matching interfacial water to reaction coordinates
Sulfur isn’t poisonous when it synergistically acts with phosphine in olefins hydroformylation
URI researchers uncover molecular mechanisms behind speciation in corals
Chitin based carbon aerogel offers a cleaner way to store thermal energy
Tracing hidden sources of nitrate pollution in rapidly changing rural urban landscapes
Viruses on plastic pollution may quietly accelerate the spread of antibiotic resistance
Three UH Rainbow Babies & Children’s faculty elected to prestigious American Pediatric Society
Tunnel resilience models unveiled to aid post-earthquake recovery
Satellite communication systems: the future of 5G/6G connectivity
Space computing power networks: a new frontier for satellite technologies
Experiments advance potential of protein that makes hydrogen sulfide as a therapeutic target for Alzheimer’s disease
Examining private equity’s role in fertility care
Current Molecular Pharmacology achieves a landmark: real-time CiteScore advances to 7.2
Skeletal muscle epigenetic clocks developed using postmortem tissue from an Asian population
Estimating unemployment rates with social media data
Climate policies can backfire by eroding “green” values, study finds
Too much screen time too soon? A*STAR study links infant screen exposure to brain changes and teen anxiety
Global psychiatry mourns Professor Dan Stein, visionary who transformed mental health science across Africa and beyond
KIST develops eco-friendly palladium recovery technology to safeguard resource security
[Press-News.org] Long-term anticoagulation discontinuation after catheter ablation for atrial fibrillationJAMA