Three high school students – Andrea Olsen from Oslo, Norway; Zachary Harpaz from Boca Raton, Florida; and Chris Ren from Shanghai, China – co-authored a paper using a generative artificial intelligence (AI) engine for target discovery from Insilico Medicine (“Insilico”) called PandaOmics to identify new therapeutic targets for glioblastoma multiforme (GBM). GBM is the most aggressive and common malignant brain tumor, accounting for 16% of all primary brain tumors. The findings were published on April 26 in the journal Aging. Olsen, a student at Sevenoaks School in Kent, UK, began interning at Insilico Medicine in 2021, after discovering ...

People often assume that the products they use every day are safe. Now a new study by Silent Spring Institute and University of California, Berkeley exposes how much people come into contact with toxic ingredients in products, used at home and at work, that could harm their health. Findings from the analysis could help state and federal agencies strengthen chemical regulations and guide manufacturers in making safer products. Many common products like shampoos, body lotions, cleaners, mothballs, and paint removers contain toxic volatile organic compounds or VOCs—chemicals that escape as gases, accumulate in indoor air, and cause a variety of health ...

There are no plants, and only very few animals: people rarely come here. The large glaciers in Greenland have long been perceived as ice deserts. Gigantic ice sheets where conditions for life are extremely harsh. But now, it seems, we have been wrong. There is much more life on the glaciers than we thought. Headed by Professor Alexandre Anesio, a group of researchers from the Department of Environmental Science at Aarhus University have discovered that the glaciers are teeming with life. Microbes that have adapted to ...

COLUMBUS, Ohio – A new study analyzing data on over 20,000 U.S. adults links a healthier diet and increased exercise to weight loss that reduces heart disease risk – while associating skipping meals and taking prescription diet pills with minimal weight loss, weight maintenance or weight gain. For many in the study sample, however, losing a “clinically significant” 5% of their body weight did not eliminate their risk factors for cardiovascular disease, results showed. In fact, the average ...

New research published in PeerJ Life and Environment by Dr. Sarah Davis and sixty-one scientists from 12 countries presents a perspective to build consensus around the assessment and interpretation of Symbiodiniaceae diversity. Symbiodiniaceae is a family of marine dinoflagellates (plankton) notable for their symbiotic associations with reef-building corals, sea anemones, jellyfish, marine sponges and other marine invertebrates. Understanding Symbiodiniaceae is important to those working to protect and regenerate coral reefs that are under threat around the world. "The authors hope this paper will provide a springboard to launch ...

The International World Wide Web Conference Committee (IW3C2) announced today that the 2023 Seoul Test of Time Award will be presented to the authors of the paper “A Contextual-Bandit Approach to Personalized News Article Recommendation;” Wei Chu, (Ant Group), Lihong Li, (Amazon), John Langford, (Microsoft) and Robert Schapire (Microsoft). The award will be presented during the opening ceremony of the 32nd international conference in The ACM Web Conference series (formerly known as The International World Wide Web Conference) hosted by the team in Austin. See https://www2023.thewebconf.org ...

NEW YORK, NY (May 2, 2023)--A study of more than 2,200 adults who attended U.S. high schools in the early 1960s found that those who attended higher quality schools had better cognitive function 60 years later.   Previous studies have found that the number of years spent in school correlates with cognition later in life, but few studies have examined the impact of educational quality.  “Our study establishes a link between high-quality education and better late-life cognition and suggests that increased investment ...

RICHLAND, Wash. –  While adding a little water is popularly thought to “open up” the flavor of whisky, a Washington State University-led study indicates there’s a point at which it becomes too much: about 20%. Researchers chemically analyzed how volatile compounds in a set of 25 whiskies responded to the addition of water, including bourbons, ryes, Irish whiskeys and both single malt and blended Scotches. They also had a trained sensory panel assess six of those whiskies, three Scotches and ...

PITTSBURGH, May 2, 2023 — In a paper published today in Communications Biology, auditory neuroscientists at the University of Pittsburgh describe a machine learning model that helps explain how the brain recognizes the meaning of communication sounds, such as animal calls or spoken words.   The algorithm described in the study models how social animals, including marmoset monkeys and guinea pigs, use sound-processing networks in their brain to distinguish between sound categories – such as calls for mating, food or danger — and act on them.   The study is an important step toward understanding the intricacies and complexities ...

Every cell in our body is able to turn genes (DNA) on or off, producing RNA, but when genes are ‘turned on’ to the wrong level it can result in a variety of health conditions. Rett syndrome is a rare neurodevelopmental condition that causes a loss of motor and language skills over time in girls. The condition is caused by a genetic variation in the MECP2 gene located on the X chromosome, resulting in affected nerve cells in the brain expressing the wrong levels of more than one thousand genes. The end result is that Rett syndrome nerve cells are smaller, less interconnected and less electrically active than healthy controls.  In ...

A new paper in the Quarterly Journal of Economics, published by Oxford University Press, indicates that an important part of the pay gap between men and women has to do with how they conduct job searches, with women more likely to accept job offers early while men tend to hold out for higher pay. Women in the United States earn 84% of what men earn, as of 2020. This disparity is well documented, and economists and the general public have known about the earnings difference for decades. The reasons for this phenomenon are a matter of considerable debate. Initial conditions in the labor market are long-lasting. Young workers who begin ...

Scientists dream of using tiny molecules as building blocks to construct things, similar to how we build things with mechanical parts. However, molecules are incredibly small - around one hundred millionth the size of a softball - and they move randomly in liquids, making it very difficult to manipulate them in a single form. To overcome this challenge, “nanofluidic devices” that can transport molecules in extremely narrow channels, similar in size to one millionth of a straw, are attracting attention ...

AMHERST, Mass. – Researchers at the University of Massachusetts Amherst and the University of Alaska Anchorage are the first to characterize two different types of surface water in the hyperarid salars—or salt flats—that contain much of the world’s lithium deposits. This new characterization represents a leap forward in understanding how water moves through such basins, and will be key to minimizing the environmental impact on such sensitive, critical habitats. “You can’t protect the salars if you don’t first understand how they work,” says Sarah McKnight, lead author of the research that appeared recently ...

Embargoed for release until 5:00 p.m. ET on Monday 01 May 2023 Annals of Internal Medicine Tip Sheet @Annalsofim Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization they represent. ---------------------------- 1. ...

Climate change has led to earlier spring blooms for wildflowers and ocean plankton but the impacts on salmon migration are more complicated, according to new research. In a new study, published in the journal Nature, Ecology & Evolution, Simon Fraser University (SFU) researcher Sam Wilson led a set of diverse collaborators from across North America to compile the largest dataset in the world on juvenile salmon migration timing. The dataset includes 66 populations from Oregon to B.C. to Alaska. Each dataset was at least 20 years in length with the longest dating back to 1951. Only wild salmon, and not salmon from hatcheries, ...

ANN ARBOR, Mich. – In recent years, experts have debated whether most birthing individuals would benefit from labor induction once they reach a certain stage of pregnancy. But a new statewide study in Michigan suggests that inducing labor at the 39th week of pregnancy for people having their first births with a single baby that is in a head down position, or low risk, doesn’t necessarily reduce the risk of caesarian births. In fact, for some birthing individuals, it may even have the opposite effect if hospitals don’t take a thoughtful approach to ...

BEND, Ore. – A researcher at Oregon State University-Cascades has received funding to develop a smart compost bin that tracks household food waste. The project led by Patrick Donnelly, assistant professor of computer science in the OSU College of Engineering, seeks to make a dent in a multi-billion-dollar annual problem in the United States: More than one-third of all food produced in the U.S. goes uneaten. “At every other step of the agricultural supply chain, food waste is tracked, measured and quantified,” Donnelly ...

DALLAS, May 1, 2023 — Science tells us that when a cardiac arrest happens, bystander CPR can double or even triple the chances of survival.[1] Asian American and Pacific Islander (AAPI) adults who experience cardiac arrest outside of a hospital setting have a substantially lower chance of receiving bystander CPR.[2] During Asian American Pacific Islander Heritage month in May, the American Heart Association, a global force for healthier lives for all, is asking people to “Be the Beat” for their family and learn Hands-Only ...

DALLAS, May 1, 2023 — Strokes can happen to anyone, at any age. In fact, globally about one in four adults over the age of 25 will have a stroke in their lifetime.[1] During American Stroke Month, the American Stroke Association, a division of the American Heart Association, as part of a nationally supported collaboration with HCA Healthcare and the HCA Healthcare Foundation, will teach people everywhere that stroke is largely preventable, treatable and beatable. A stroke happens when normal blood flow in the brain is interrupted. When parts of the ...

AUGUSTA, Ga. (May 2, 2023) – Inhibiting a tiny RNA whose levels significantly increase with age, along with problems like weaker bones and sagging muscles, may be a way to keep our bodies more youthful and healthy, scientists say.  MicroRNAs help regulate gene expression and consequently the function of our cells, and several, including one called microRNA-141-3p, have been implicated in the ills of aging, like increasing levels of potentially damaging chronic inflammation and that shrinking muscle mass. “When we age in all these complications like chronic inflammation, muscle loss, bone loss, this microRNA is elevated,” says Sadanand ...

HOUSTON – (May 2, 2023) – Feces from fish that are typically thought to promote healthy reefs can damage and, in some cases, kill corals, according to a recent study by Rice University marine biologists. Until recently, fish that consume algae and detritus — grazers — were thought to keep reefs healthy, and fish that eat coral — corallivores — were thought to weaken reef structures. The researchers found high levels of coral pathogens in grazer feces and high levels of beneficial bacteria in corallivore feces, which they say could act like a “coral probiotic.” “Corallivorous ...

New findings in color vision research imply that humans can perceive a greater range of blue tones than monkeys do. “Distinct connections found in the human retina may indicate recent evolutionary adaptations for sending enhanced color vision signals from the eye to the brain,” researchers report April 25 in the scientific journal, Proceedings of the National Academy of Sciences. Yeon Jin Kim, acting instructor, and Dennis M. Dacey, professor, both in the Department of Biological Structure at the University of Washington School of Medicine in Seattle, led the international, collaborative project. They were joined ...

INFORMS Journal Manufacturing & Service Operations Management New Study Key Takeaways: Matching supply and demand of organs can provide broader sharing in a way that results in greater transplant equity. By indiscriminately enlarging the pool of supply locations from where patients can receive offers, they tend to become more selective, resulting in more offer rejections and less efficiency. The model accounts for the variation of “incidence of disease” (i.e., demand) and “availability of deceased-donor organs” ...

TAMPA, Fla. (May 1, 2023) – Subglacial lakes that never see the light of day are among the least accessible frontiers of science, brimming with more tales yet untold than even the planets of our solar system. One thing seems certain: where there is water, there is life -- even if said water is at the bottom of a frigid lake, in pitch darkness, below more than a half mile of the West Antarctic Ice Sheet. As reported in AGU Advances, scientists analyzed the chemical fingerprint of the ocean and microbes retrieved from sediments and water at the bottom of a subglacial ...

  Images  //  Video  Couches, tables, sleeves and more can turn into a high-fidelity input device for computers using a new sensing system developed at the University of Michigan.   The system repurposes technology from new bone-conduction microphones, known as Voice Pickup Units (VPUs), which detect only those acoustic waves that travel along the surface of objects. It works in noisy environments, along odd geometries such as toys and arms, and on soft fabrics such as clothing and furniture.    Called SAWSense, for the surface acoustic waves it relies ...