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Climate change influences river flow

2021-03-11
Climate change is affecting the water balance of our planet: depending on the region and the time of year, this can influence the amount of water in rivers potentially resulting in more flooding or drought. River flow is an important indicator of water resources available to humans and the environment. The amount of available water also depends on further factors, such as direct interventions in the water cycle or land use change: if, for example, water is diverted for irrigation or regulated via reservoirs, or forests are cleared and monocultures grown in their place, this can have an impact on river flow. However, how river flow ...

Polarization: From better sunglasses to a better way of looking at asteroid surfaces

Polarization: From better sunglasses to a better way of looking at asteroid surfaces
2021-03-11
Using the same principles that make polarized sunglasses possible, a team of researchers at the Arecibo Observatory in Puerto Rico have developed a technique that will help better defend against asteroids on a collision course with Earth. A new study recently published in The Planetary Science Journal found a better way to interpret radar signals bounced off asteroids' surfaces. The data can better tell us if an asteroid is porous, fluffy or rocky, which matters because there are hundreds of near-Earth asteroids that could potentially hit the planet. "Learning more about the physical properties of asteroids is crucial in Planetary Defense," says Dylan Hickson the lead author and a research scientist at the Arecibo Observatory in Puerto Rico. "A porous, fluffy asteroid does ...

Hubble sees new atmosphere forming on a rocky exoplanet

Hubble sees new atmosphere forming on a rocky exoplanet
2021-03-11
The planet GJ 1132 b appears to have begun life as a gaseous world with a thick blanket of atmosphere. Starting out at several times the radius of Earth, this so-called "sub-Neptune" quickly lost its primordial hydrogen and helium atmosphere, which was stripped away by the intense radiation from its hot, young star. In a short period of time, it was reduced to a bare core about the size of Earth. To the surprise of astronomers, new observations from Hubble [1] have uncovered a secondary atmosphere that has replaced the planet's first atmosphere. It is rich in hydrogen, hydrogen cyanide, methane and ammonia, and also has a hydrocarbon haze. Astronomers theorise that hydrogen from the original atmosphere was absorbed into the planet's molten magma mantle and is now being slowly released ...

New insight into how cancer spreads

New insight into how cancer spreads
2021-03-11
Breast cancer is harmful enough on its own, but when cancer cells start to metastasize -- or spread into the body from their original location -- the disease becomes even more fatal and difficult to treat. Thanks to new research published in Oncogene from the lab of University of Colorado Cancer Center associate director of basic research Heide Ford, PhD, in collaboration with Michael Lewis, PhD, from Baylor College of Medicine, doctors may soon have a better understanding of one mechanism by which metastasis happens, and of potential ways to slow it down. "Metastasis is a huge problem nobody's tackled very well," says Ford, who ...

Laser-driven experiments provide insights into the formation of the universe

2021-03-11
The universe is filled with magnetic fields. Understanding how magnetic fields are generated and amplified in plasmas is essential to studying how large structures in the universe were formed and how energy is divided throughout the cosmos. An international collaboration, co-led by researchers at the University of Rochester, the University of Oxford, and the University of Chicago, conducted experiments that captured for the first time in a laboratory setting the time history of the growth of magnetic fields by the turbulent dynamo, a physical mechanism thought to be responsible for generating ...

Simultaneous multicontrast OR-PAM from single laser source

Simultaneous multicontrast OR-PAM from single laser source
2021-03-11
Optical-resolution photoacoustic microscopy (OR-PAM), a new hybrid imaging technique, allows us to listen to the sound of light and see the color of biological tissue itself. It can be used for live, multicontrast functional imaging, but the limited wavelength choice of most commercial lasers and the limitations of the existing scanning methods have meant that OR-PAM can obtain only one or two different types of contrast in a single scan. These limitations have made multicontrast functional imaging time-consuming, and it's been difficult to capture the ...

Black and Hispanic workers overrepresented in occupations with higher risk for COVID-19 exposure

2021-03-11
Ann Arbor, March 11, 2020 - Black and Hispanic people experience a higher risk for COVID-19 and severe illness, influenced by factors such as discrimination, housing, and healthcare access and utilization. Now, a END ...

'Hunker down' stress genes boosted in women who live in violent neighborhoods

Hunker down stress genes boosted in women who live in violent neighborhoods
2021-03-11
CHAMPAIGN, Ill. -- The chronic stress of living in neighborhoods with high rates of violence and poverty alters gene activity in immune cells, according to a new study of low-income single Black mothers on the South Side of Chicago. The changes in stress-related gene expression reflect the body's "hunker down" response to long-term threat, a physiological strategy for lying low and considering new actions rather than launching an immediate "fight-or-flight" response. This has implications for health outcomes in communities of color and other marginalized populations, said researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Kentucky and UCLA. The researchers published the study in the journal Psychoneuroendocrinology. "The ...

Birds learn to avoid flashy, hard-to-catch butterflies and their lookalikes

Birds learn to avoid flashy, hard-to-catch butterflies and their lookalikes
2021-03-11
GAINESVILLE, Fla. --- The showy colors of some butterflies could advertise their speed and nimbleness, much like a coat of bright yellow paint on a sports car. A new study shows birds can learn to recognize these visual cues, avoiding not only butterflies they've failed to nab in the past but similar-looking species as well. The research provides some of the strongest evidence to date for the idea of evasive mimicry, a strategy in which animals protect themselves from predators by matching the colors or patterns of agile relatives. First proposed more than 60 years ago, the hypothesis has been a challenge to test. But in an experimental setting, ...

Early tracheotomy helps patients avoid ventilator-associated pneumonia, team finds

2021-03-11
SAN ANTONIO -- Surgically opening the windpipe, or trachea, within the first seven days of the start of mechanical ventilation decreases the time patients spend on ventilators, shortens their ICU stay and lowers their risk of ventilator-associated pneumonia, according to a systematic review published Thursday (March 11) in JAMA Otolaryngology-Head & Neck Surgery. "We analyzed the existing medical literature to unravel a question that is very pertinent to adult critical care," said senior author Alvaro Moreira, MD, MSc, of The University of Texas Health Science Center at San Antonio (UT Health San ...

Global battle against antibiotic resistance requires tailored solutions

2021-03-11
The global battle against antibiotic resistance can only succeed if local contexts are taken into account. "A tailored approach is needed in each country," says Heiman Wertheim of Radboud university medical center. "There is no "one-size-fits-all' solution." This was the main finding of a study on antibiotic resistance in African and Asian countries funded by the British Wellcome Trust. Wertheim is the lead investigator of a large group of international researchers who recently published an article on this study in The Lancet Global Health. Antibiotics are powerful treatments for bacterial infections. They are indispensable for controlling infections such as pneumonia, meningitis, or blood poisoning (sepsis) caused by bacteria. But they are ineffective for treating ...

New tool to dissect the "undruggable"

New tool to dissect the undruggable
2021-03-11
Sugar has been called "evil," "toxic," and "poison." But the body needs sugars, too. Sugar molecules help cells recognize and fight viruses and bacteria, shuttle proteins from cell to cell, and make sure those proteins function. Too much or too little can contribute to a range of maladies, including neurodegenerative diseases like Alzheimer's, inflammation, diabetes, and even cancer. About 85 percent of proteins, including those associated with Alzheimer's and Parkinson's, are beyond the reach of current drugs. One critical and abundant sugar (O-GlcNAc, pronounced o-glick-nack) is found on over 5,000 proteins, often those considered "undruggable." But now, researchers at Harvard University ...

HPV vaccines for adults over age 26 may not be cost-effective

2021-03-11
Boston, MA - Vaccinating adults age 26 and older against the human papillomavirus (HPV)--the virus that causes more than 90% of cervical cancers as well as several other cancers--may not be cost-effective, according to a new study led by researchers at the Harvard T.H. School of Public Health. "Our study found that the added health benefit of increasing the vaccination age limit beyond 26 years is minimal, and that the cost-effectiveness is much lower than in pre-adolescents, the target age group for the HPV vaccine," said Jane Kim, K.T. Li Professor of Health Economics and lead author of the study. The study will be published March 11, 2021, in PLOS Medicine. HPV vaccines have been shown to be highly effective in preventing ...

Foodborne fungus impairs intestinal wound healing in Crohn's disease

2021-03-11
Eating is a dangerous business. Naturally occurring toxins in food and potentially harmful foodborne microbes can do a number on our intestines, leading to repeated minor injuries. In healthy people, such damage typically heals in a day or two. But in people with Crohn's disease, the wounds fester, causing abdominal pain, bleeding, diarrhea and other unpleasant symptoms. Researchers at Washington University School of Medicine in St. Louis and the Cleveland Clinic have discovered that a fungus found in foods such as cheese and processed meats can infect sites of intestinal damage in mice and people with Crohn's and prevent healing. Moreover, treating infected mice with antifungal medication eliminates the fungus and allows the wounds ...

AI analysis of how bacteria attack could help predict infection outcomes

2021-03-11
Insights into how bacterial proteins work as a network to take control of our cells could help predict infection outcomes and develop new treatments. Much like a hacker seizes control of a company's software to cause chaos, disease-causing bacteria, such as E. coli and Salmonella, use miniature molecular syringes to inject their own chaos-inducing agents (called effectors) into the cells that keep our guts healthy. These effectors take control of our cells, overwhelming their defences and blocking key immune responses, allowing the infection to take hold. Previously, studies have investigated single effectors. Now a team led by scientists at Imperial College London and The Institute of Cancer ...

Contactless high performance power transmission

Contactless high performance power transmission
2021-03-11
A team led by Christoph Utschick and Prof. Rudolf Gross, physicists at the Technical University of Munich (TUM), has developed a coil with superconducting wires capable of transmitting power in the range of more than five kilowatts contactless and with only small losses. The wide field of conceivable applications include autonomous industrial robots, medical equipment, vehicles and even aircraft. Contactless power transmission has already established itself as a key technology when it comes to charging small devices such as mobile telephones and electric toothbrushes. Users would also like to see contactless charging made available for larger electric machines such as industrial robots, medical equipment and electric vehicles. Such devices could ...

How to make all headphones intelligent

How to make all headphones intelligent
2021-03-11
How do you turn "dumb" headphones into smart ones? Rutgers engineers have invented a cheap and easy way by transforming headphones into sensors that can be plugged into smartphones, identify their users, monitor their heart rates and perform other services. Their invention, called END ...

UCI-led team creates new ultralightweight, crush-resistant tensegrity metamaterials

UCI-led team creates new ultralightweight, crush-resistant tensegrity metamaterials
2021-03-11
Irvine, Calif., March 11, 2021 - Catastrophic collapse of materials and structures is the inevitable consequence of a chain reaction of locally confined damage - from solid ceramics that snap after the development of a small crack to metal space trusses that give way after the warping of a single strut. In a study published this week in Advanced Materials, engineers at the University of California, Irvine and the Georgia Institute of Technology describe the creation of a new class of mechanical metamaterials that delocalize deformations to prevent failure. They did so by turning to tensegrity, a century-old design principle in which isolated ...

Researchers boost potency of an HIV-1 antibody, tracing new pathways for vaccine development

Researchers boost potency of an HIV-1 antibody, tracing new pathways for vaccine development
2021-03-11
LAWRENCE -- Much like coronavirus, circulating HIV-1 viruses mutate into diverse variants that pose challenges for scientists developing vaccines to protect people from HIV/AIDS. "AIDS vaccine development has been a decades-long challenge partly because our immune systems have difficulty recognizing all the diverse variants of the rapidly mutating HIV virus, which is the cause of AIDS," said Brandon DeKosky, assistant professor of pharmaceutical chemistry and chemical & petroleum engineering at the University of Kansas. In the past five years, tremendous progress has been ...

CHOP researchers reveal how critical part of lung forms at cellular level

2021-03-11
Philadelphia, March 12, 2021 - Researchers from Children's Hospital of Philadelphia (CHOP) have determined what happens at a cellular level as the lung alveolus forms and allows newborns to breathe air. Understanding this process gives researchers a better sense of how to develop therapies and potentially regenerate this critical tissue in the event of injury. The findings were published online today by the journal Science. The lung develops during both embryonic and postnatal stages, during which lung tissue forms and a variety of cell types perform specific roles. During the transition from embryo to newborn is when the alveolar region of the lung ...

Skoltech team shows how Turing-like patterns fool neural networks

2021-03-11
Skoltech researchers were able to show that patterns that can cause neural networks to make mistakes in recognizing images are, in effect, akin to Turing patterns found all over the natural world. In the future, this result can be used to design defenses for pattern recognition systems currently vulnerable to attacks. The paper, available as an arXiv preprint, was presented at the 35th AAAI Conference on Artificial Intelligence (AAAI-21). Deep neural networks, smart and adept at image recognition and classification as they already are, can still be vulnerable ...

Scientists discover cellular stress enzyme that might play key role in neurodegenerative diseases such as ALS

2021-03-11
An enzyme called MARK2 has been identified as a key stress-response switch in cells in a study by researchers at Johns Hopkins Bloomberg School of Public Health. Overactivation of this type of stress response is a possible cause of injury to brain cells in neurodegenerative diseases such as Alzheimer's, Parkinson's, and Amyotrophic Lateral Sclerosis. The discovery will make MARK2 a focus of investigation for its possible role in these diseases, and may ultimately be a target for neurodegenerative disease treatments. In addition to its potential relevance to neurodegenerative diseases, the finding is an advance in understanding basic cell biology. The paper describing ...

Cheaper carbon capture is on the way

Cheaper carbon capture is on the way
2021-03-11
RICHLAND, Wash.--As part of a marathon research effort to lower the cost of carbon capture, chemists have now demonstrated a method to seize carbon dioxide (CO2) that reduces costs by 19 percent compared to current commercial technology. The new technology requires 17 percent less energy to accomplish the same task as its commercial counterparts, surpassing barriers that have kept other forms of carbon capture from widespread industrial use. And it can be easily applied in existing capture systems. In a study published in the March 2021 edition of International Journal of Greenhouse Gas Control, researchers from the U.S. Department of Energy's Pacific Northwest National Laboratory--along with collaborators from ...

Weakened protections led to more disappearances of endangered Mexican wolves

2021-03-11
MADISON, Wis. -- Mexican wolves in the American Southwest disappeared more quickly during periods of relaxed legal protections, almost certainly succumbing to poaching, according to new research published Wednesday. Scientists from the University of Wisconsin-Madison found that Mexican wolves were 121% more likely to disappear -- despite high levels of monitoring through radio collars -- when legal rulings permitted easier lethal and non-lethal removal of the protected wolves between 1998 and 2016. The disappearances were not due to legal removal, the researchers say, but instead were likely caused by poachers hiding evidence of their activities. The findings suggest that consistently strong protections for endangered predators lead ...

Paleontology: Microscope helps with dinosaur puzzle

Paleontology: Microscope helps with dinosaur puzzle
2021-03-11
Fossil sites sometimes resemble a living room table on which half a dozen different jigsaw puzzles have been dumped: It is often difficult to say which bone belongs to which animal. Together with colleagues from Switzerland, researchers from the University of Bonn have now presented a method that allows a more certain answer to this question. Their results are published in the journal Palaeontologia Electronica. Fossilized dinosaur bones are relatively rare. But if any are found, it is often in large quantities. "Many sites contain the remains of dozens of animals," explains Prof. Dr. Martin Sander from the Institute ...
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