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New drug combination treats hepatitis C patients also infected with HIV

2015-07-22
Roughly 20 to 30 percent of patients with hepatitis C virus (HCV) are also infected with human immunodeficiency virus type 1 (HIV). Both blood-borne viruses share the same modes of transmission, but many HCV medications currently have significant limitations due to adverse interactions with HIV treatments. Researchers at University of California, San Diego School of Medicine report a new combination that effectively treats HCV in patients co-infected with HIV. The study, published online in the New England Journal of Medicine, found the combination of HCV drugs daclatasvir ...

Low-nicotine cigarettes fail to sway smokers

2015-07-22
Smokers who successfully lowered their nicotine intake when they were switched to low-nicotine cigarettes were unable to curb their smoking habits in the long term, according to a study by researchers at UCSF and San Francisco General Hospital and Trauma Center. The study, published online today (July 22) in the journal Addiction found that levels of cotinine, a derivative of nicotine measured in the blood, plummeted six months after smokers' regular cigarettes were replaced with low-nicotine ones. But levels started to rebound later into the study when smokers returned ...

Hair ice mystery solved

Hair ice mystery solved
2015-07-22
You may have never seen or heard of it, but hair ice - a type of ice that has the shape of fine, silky hairs and resembles white candy floss - is remarkable. It grows on the rotten branches of certain trees when the weather conditions are just right, usually during humid winter nights when the air temperature drops slightly below 0°C. Now, a team of scientists in Germany and Switzerland have identified the missing ingredient that gives hair ice its peculiar shape: the fungus Exidiopsis effusa. The research is published today (22 July) in Biogeosciences, an open access ...

Having wealthy neighbors may skew beliefs about overall wealth distribution

2015-07-22
Wealthy people may be likely to oppose redistribution of wealth because they have biased information about how wealthy most people actually are, according to new research published in Psychological Science, a journal of the Association for Psychological Science. The findings indicate that people use their own neighborhoods and communities as a gauge of how much wealth other people possess, leading wealthy people to perceive the broader population as being wealthier than it actually is. "If you're rich, there's a good chance you know lots of other rich people and relatively ...

Current dietary protein recommendations need updating

2015-07-22
New research based on modern techniques suggests that recommendations for protein intake in healthy populations may be incorrect. In a paper just published in Applied Physiology, Nutrition, and Metabolism, an NRC Research Press journal (a division of Canadian Science Publishing), researchers put the focus on protein as an essential component of a healthy diet. Protein helps people stay full longer, preserve muscle mass, and when combined with adequate physical activity, has the potential to serve as a key nutrient for important health outcomes and benefits. It's not ...

New evidence of cultural diversification between neighboring chimpanzee communities

New evidence of cultural diversification between neighboring chimpanzee communities
2015-07-22
For centuries it has been thought that culture is what distinguishes humans from other animals, but over the past decade this idea has been repeatedly called into question. Cultural variation has been identified in a growing number of species in recent years, ranging from primates to cetaceans. Chimpanzees, our closest living relatives, show the most diverse cultures aside from humans, most notably, in their use of a wide variety of tools. The method traditionally used to establish the presence of culture in wild animals compares behavioural variation across populations ...

A dictionary of the language of cells

2015-07-22
In their struggle to survive and prosper, multicellular organisms rely on a complex network of communication between cells, which in humans are believed to number about 40 trillion. Now, in a study published in Nature Communications, a research group led by scientists from the RIKEN Center for Life Science Technologies (CLST) has published an overall map of how the cells in the human body communicate by systematically analyzing the relationship between ligands--substances such as insulin and interferon that embody messages between cells, and receptors--the proteins on cell ...

Targeting the strain of bacteria that causes ulcers may help prevent stomach cancer

2015-07-22
A new review published in the Cochrane Library, indicates that eradicating Helicobacter pylori bacterium-- the main cause of stomach ulcers - with a short course of therapy comprising two commonly used medicines may help to reduce the risk of gastric cancer. Stomach, or gastric, cancer is the third most common cause of death from cancer worldwide, and people who are infected with the Helicobacter pylori bacterium are more likely to develop the disease. About two-thirds of us have H. pylori in our bodies, but in most cases we experience no discomfort or other symptoms. ...

Progressively reducing the nicotine content of cigarettes may not lead smokers to quit

2015-07-22
The US Family Smoking Prevention and Tobacco Control Act, passed in 2009, permits the U.S. Food and Drug Administration (FDA) to set standards for cigarette nicotine content. The FDA is accordingly supporting research into how very low nicotine content (VLNC) cigarettes might function as a regulatory measure to make cigarettes non-addictive, reduce smoke exposure, and improve public health, even among people who don't want to quit smoking. New research published today in the scientific journal Addiction shows that simply reducing the nicotine content of cigarettes may ...

HIV treatment has social and socioeconomic benefits, as well as improved health: Study

2015-07-22
New research shows that HIV treatment for illicit drug users improves their social and socioeconomic wellbeing as well as their health. While the health benefits of antiretroviral therapy (ART) for HIV are well documented, less is known about possible secondary benefits. Lindsey Richardson, an assistant professor in the Department of Sociology at the University of British Columbia and research scientist with the BC Centre for Excellence in HIV/AIDS (BC-CfE), presented findings from two studies July 22 at the International AIDS Society (IAS) Conference in Vancouver. ...

Selfishness lasts a lifetime, according to mongoose study

Selfishness lasts a lifetime, according to mongoose study
2015-07-22
Researchers studying wild banded mongooses in Uganda have discovered that these small mammals have either cooperative or selfish personalities which last for their entire lifetime. The findings of the 15-year study are published today in the journal Animal Behaviour. The researchers investigated the selfish behaviour of mongoose mate-guarding - where dominant males guard particular females - and the cooperative behaviour of 'babysitting' and 'escorting' the young. They found that cooperative mongooses that helped out with offspring care did so consistently over their ...

Regular consumption of sugary drinks associated with type 2 diabetes

2015-07-22
Regular consumption of sugar sweetened drinks is positively associated with type 2 diabetes independent of obesity status, finds a study published in The BMJ this week. Artificially sweetened drinks and fruit juice also showed a positive association with type 2 diabetes, but the quality of evidence was limited. None the less, the authors warn that neither artificially sweetened drinks nor fruit juice are suitable alternatives to sugar sweetened drinks for the prevention of type 2 diabetes. Artificially sweetened beverages have been seen as possible alternatives to ...

Both birth weight and adult lifestyle influence diabetes risk

2015-07-22
A low birth weight combined with an unhealthy lifestyle in adulthood are jointly related to an increased risk of type 2 diabetes, finds a study published in The BMJ this week. The researchers say their findings emphasise the importance of adopting a healthy lifestyle to prevent the majority of type 2 diabetes cases in the population. Diabetes has become a global epidemic, with an estimated 387 million living with diabetes and 4.9 million attributable deaths in 2014. Both unhealthy lifestyles and early life development have been implicated in the rapid rise of type 2 ...

Commercial ties may be fueling unnecessary and potentially harmful osteoporosis treatment

2015-07-22
A complex web of interactions between industry, advocacy organisations, and academia may be fuelling enthusiasm for calcium and vitamin D supplements to prevent and treat osteoporosis, despite evidence of lack of benefit, warn doctors in The BMJ this week. Calcium and vitamin D are highly profitable treatments that are widely recommended for osteoporosis, despite increasing evidence contradicting the practice, write Andrew Grey and Mark Bolland from the University of Auckland. Several therapies previously recommended for osteoporosis, such as oestrogen and fluoride, ...

Doctors and medical students in India should stop wearing white coats

2015-07-22
Doctors and medical students in India should stop wearing white coats, argues a doctor in The BMJ this week. Edmond Fernandes, a postgraduate at Yenepoya Medical College in Mangalore, says evidence shows that long sleeved coats spread infection and lead to avoidable harm and cost to patients. Although long sleeved white coats have traditionally been worn by doctors since the 19th century, we now know that white coats "harbour potential contaminants and contribute considerably to the burden of disease acquired in hospital by spreading infection," writes Fernandes. He ...

Low birth weight combined with unhealthy adult lifestyle may increase type 2 diabetes risk

2015-07-22
Boston, MA -- People who are a low weight at birth and have unhealthy habits as adults, such as eating nutritionally poor diets or smoking, may have a greater risk of developing type 2 diabetes than people born at an average weight who live similar lifestyles, according to a new study led by researchers from Harvard T.H. Chan School of Public Health. In the first study to comprehensively assess how early development interacts with adult behavior to influence type 2 diabetes risk, the researchers found that 18% of cases were attributable to the combined effect of low birth ...

Keeping up that positive feeling: The science of savoring emotions

2015-07-22
MADISON, Wis. - Savoring a beautiful sunset and the positive emotions associated with it can contribute to improved well-being, according to research. But why and how are some people better than others in keeping the feeling alive? "It's important to consider not just how much emotion you experience, but also how long these emotions persist," says Aaron Heller, former graduate student at the University of Wisconsin-Madison Center for Investigating Healthy Minds (CIHM) at the Waisman Center and current assistant professor of psychology at the University of Miami. "We're ...

Choosing Wisely in newborn medicine: Improving health outcomes, reducing costs

2015-07-21
BOSTON - Advances in technology have spurred better outcomes for infants treated in neonatal intensive care units, but parents and physicians need to work together to avoid unnecessary and potentially harmful tests and treatments, according to new Choosing Wisely® recommendations developed by neonatologists at Beth Israel Deaconess Medical Center (BIDMC) and published online in Pediatrics, the scientific journal of the American Academy of Pediatrics (AAP). "Infant mortality has dropped dramatically over the past 50 years, with almost all of the impact resulting from ...

Cellphones seen as change agents for health among young, poor, urban women

2015-07-21
In a survey of a diverse group of almost 250 young, low-income, inner-city pregnant and postpartum women, Johns Hopkins researchers have learned that more than 90 percent use smartphones or regular cellphones to give and get information. In a report on the survey, published online in July in the Journal of Internet Medicine Research, the research team says the findings strongly confirm the potential of the devices as a desireable means of improving the health of those at risk for diabetes and other diseases during their childbearing years. Cellphones stand out by far ...

Why we live on Earth and not Venus

2015-07-21
Compared to its celestial neighbours Venus and Mars, Earth is a pretty habitable place. So how did we get so lucky? A new study sheds light on the improbable evolutionary path that enabled Earth to sustain life. The research, published this week in Nature Geoscience, suggests that Earth's first crust, which was rich in radioactive heat-producing elements such as uranium and potassium, was torn from the planet and lost to space when asteroids bombarded the planet early in its history. This phenomenon, known as impact erosion, helps explain a landmark discovery made ...

Study suggests new treatment avenue to prevent serous retinal detachment

2015-07-21
Philadelphia, PA, July 21, 2015 - Wet age-related macular degeneration (AMD) is the leading cause of severe vision loss in older individuals. AMD and other serious chronic eye problems that affect younger individuals result when fluid accumulates abnormally under or within the retina. A new study published in The American Journal of Pathology shows for the first time that the release of substances from mast cells may be a causal factor in this type of eye pathology, and inhibitors of this release may offer new ways to treat serous retinal detachment. Mast cells are white ...

Drawing a line between quantum and classical world

2015-07-21
Quantum theory is one of the great achievements of 20th century science, yet physicists have struggled to find a clear boundary between our everyday world and what Albert Einstein called the "spooky" features of the quantum world, including cats that could be both alive and dead, and photons that can communicate with each other across space instantaneously. For the past 60 years, the best guide to that boundary has been a theorem called Bell's Inequality, but now a new paper shows that Bell's Inequality is not the guidepost it was believed to be, which means that as the ...

Forages and Pastures Symposium leads to 3 new papers in Journal of Animal Science

2015-07-21
July 2, 2015 - Feed and production input costs are the primary economic inputs of the cattle industry. As input costs increase, producers and cattle are asked to be more efficient to satisfy global food demands. Furthermore, the amount of land available for cattle production in the United States has decreased over the past 10 years. Improvements with marginal land and marginal-quality harvested feeds are being considered. Three studies were recently published in the Journal of Animal Science that were highlighted at the Forages and Pastures Symposium at JAM in 2015 titled ...

Stress 'sweet spot' differs for mellow vs. hyper dogs

2015-07-21
DURHAM, N.C. -- People aren't the only ones who perform better on tests or athletic events when they are just a little bit nervous -- dogs do too. But in dogs as in people, the right amount of stress depends on disposition. A new study by researchers at Duke University finds that a little extra stress and stimulation makes hyper dogs crack under pressure but gives mellow dogs an edge. The findings appear online in the journal Animal Cognition. According to an idea in psychology called the Yerkes-Dodson law, a little stress can be a good thing, but only up to a point. ...

Class of diabetes medication associated with lower incidence of Parkinson's disease

2015-07-21
A class of drugs used to treat diabetes may be associated with protection against Parkinson's disease (PD), according to research published this week in PLOS Medicine. The study, conducted by Dr. Ruth Brauer, of the London School of Hygiene & Tropical Medicine, found a lower incidence of PD among people using a glitazone drug (either rosiglitazone or pioglitazone) to treat diabetes when compared to people who had used different treatments for diabetes. The cohort study was conducted using data from the UK Clinical Practice Research Datalink, and compared individuals with ...
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