ROCHESTER, Minn. -- Treating transplant patients with mild to moderate cases of COVID-19 with monoclonal antibodies is safe and helps prevent serious illness, according to a Mayo Clinic study recently published in Open Forum Infectious Diseases. These results are especially important because transplant patients who are infected with COVID-19 have a higher risk of severe illness and death. "Monoclonal antibody therapy is really important for the transplant population because they are less likely to develop their own immunity. Providing them with these antibodies helps them recover from COVID-19," says Raymund Razonable, M.D., a Mayo Clinic infectious diseases specialist and the study's senior ...

When herring are filleted, more than half their weight becomes a low-value 'side stream' that never reaches our plates - despite being rich in protein and healthy omega-3 fatty acids. Now, scientists from Chalmers University of Technology, Sweden, have developed a special dipping solution, with ingredients including rosemary extract and citric acid, which can significantly extend the side streams' shelf life, and increase the opportunities to use them as food. Techniques for upgrading these side-streams to food products such as minces, protein isolates, hydrolysates and oils are already available today, and offer the chance to reduce the current practices of using them for animal feed, ...

For over a century, researchers have known about "the bends", a serious condition affecting scuba divers. However, we still know relatively little about its physiological basis. Doctors do not yet have a definitive test for the bends, instead relying on symptoms to diagnose it. A new study in Frontiers in Physiology is the first to investigate genetic changes in divers with this condition, finding that genes involved in inflammation and white blood cell activity are upregulated. The findings cast light on the processes underlying the bends, and may lead to biomarkers that will help doctors to diagnose the condition more precisely. The bends, more formally known as decompression sickness, is a potentially lethal condition that can affect divers. Symptoms ...

BOSTON -- Obesity increases one's risk for many diseases and often prevents patients from receiving other necessary medical procedures. One of the most effective ways for patients with severe obesity to lose weight is through bariatric surgery, but it's not clear how often this option is raised. In a new study published in Obesity, investigators from Brigham and Women's Hospital find that eligible patients who discuss bariatric surgery options with their primary care providers or specialists from disciplines ranging from cardiology to urology are more likely to undergo surgery and lose more weight than ...

Previous studies have shown that children with attention difficulties and/or ADHD solve cognitive tasks better when they are exposed to auditory white noise. However, this is the first time that such a link has been demonstrated between visual white noise and cognitive abilities such as memory, reading and non-word decoding in children with reading and writing difficulties. "The white noise to which we exposed the children, also called visual pixel noise, can be compared with giving children glasses. The effect on reading and memory was immediate," explains Göran Söderlund, Senior Lecturer in Education at the University of Gothenburg and Professor of Special Education at the Western Norway University ...

People who are more prone to boredom and who are socially conservative are more likely to break public-health rules, according to new psychology research. While previous research demonstrated a connection between being highly prone to boredom and breaking social-distancing rules, this study demonstrated the association was more prominent as participants' social conservatism increased. "Many public-health measures such as wearing a mask or getting a vaccine have become highly politicized," said James Danckert, professor of psychology at the University of Waterloo. "People who find these ...

PITTSBURGH, June 10, 2021 - Americans are consuming more craft beer with higher alcohol content but are drinking less beer by volume, according to a new analysis led by epidemiologists at the University of Pittsburgh Graduate School of Public Health. The study, published online and in a coming issue of the journal Substance Use & Misuse, looked at beer purchased in stores between 2004 and 2014. This is the first study to examine trends not only in the volume of beer purchased, but also the "beer specific" alcohol content. "With the rise in popularity of craft breweries and the acquisition of such breweries by large-scale ...

India's national government has inappropriately prioritised people for covid-19 vaccination Current approach is causing huge numbers of avertable deaths, warn experts India's national government has inappropriately prioritised people for covid-19 vaccination, argue doctors and researchers in The BMJ today. Peter Lloyd-Sherlock and colleagues warn that the government's current approach to vaccination - focusing on younger age groups - "is causing huge numbers of avertable deaths and is deeply inequitable." From 3 May to 5 June 2021, more first doses were administered to people under 45 than over 60, even though at ...

HOUSTON -- Results from the multi-cohort Phase I/II ARROW clinical trial, conducted by The University of Texas MD Anderson Cancer Center researchers, showed that a once-daily dose of pralsetinib, a highly selective RET inhibitor, was safe and effective in treating patients with advanced RET fusion-positive non-small cell lung cancer (NSCLC) and RET-altered thyroid cancer. The findings for each cohort were published today in The Lancet Oncology and The Lancet Diabetes & Endocrinology, respectively. "Targeted therapies have dramatically improved care for patients with NSCLC and thyroid cancer driven by oncogenes, and the rapid clinical translation of selective RET inhibitor ...

The moons of planets that have no parent star can possess an atmosphere and retain liquid water. Astrophysicists at LMU have calculated that such systems could harbor sufficient water to make life possible - and sustain it. Water - in liquid form - is the elixir of life. It made life possible on Earth and is indispensable for the continuing existence of living systems on the planet. This explains why scientists are constantly on the lookout for evidence of water on other solid bodies in the Universe. Up to now, however, the existence of liquid water on planets other than Earth has not been directly proven. However, ...

The increased use of ridesharing apps was linked to a decrease in motor vehicle collisions and impaired driving convictions in Houston, according to published research by The University of Texas Health Science Center at Houston (UTHealth). The findings were published today in JAMA Surgery. Christopher Conner, MD, PhD, neurosurgery resident in the Vivian L. Smith Department of Neurosurgery at McGovern Medical School at UTHealth and the study's lead author, said the research is timely as more individuals are utilizing ridesharing apps. "Automobile accidents are the leading cause of death and disability among young people, so anything we can do to reduce those incidents ...

Prostate cancer is the second most common cancer among men, according to the American Cancer Society. It's also one of the trickiest cancers to diagnose and treat. But new research from the University of Georgia has identified a protein that appears to prevent the cancer from spreading to and colonizing the bone, providing a new target for future therapeutics. "Unfortunately, prostate cancer that has spread to the bone is very aggressive, often lethal and very difficult to treat," said Brian Cummings, corresponding author of the study and head of the College of Pharmacy's pharmaceutical and biomedical sciences department. "Even in cases of successful treatment, the patient's quality of life is severely lessened due to bone loss." Prostate cancer that hasn't spread beyond nearby ...

There are still many unsolved mysteries about the human brain and its development. Now, a novel study published in Frontiers in Psychiatry sheds new light on the neurobiological origins of our individual traits. Functional connectivity is the coordinated activity - activation or deactivation - through time between separate brain regions, regardless of their physical closeness or the type of neural connections between them. Changes in functional connectivity can be a sign of mental health disorders such as depression, eating disorders, and schizophrenia, and are thought to have developmental origins. We know that mental health is characterized by three functional brain networks. The first is hypoconnectivity ...

People who have a high sensation-seeking personality trait may be more likely to develop an addiction to cocaine, according to a Rutgers study. "Although many people try illicit drugs like cocaine or heroin, only a small proportion develop an addiction," said lead author Morgan James, a member of the Rutgers Brain Health Institute and an assistant professor in the department of psychiatry at Rutgers Robert Wood Johnson Medical School. "The interaction found between sensation-seeking traits and the drug-taking experience show that predisposition to addiction has a genetic basis, and that this interacts with environmental factors such as patterns of drug use. The sensation-seeking trait was predictive of rats' likelihood to exhibit stronger ...

For older adults, participating in social activities can protect against physical and mental signs of aging, but it may also pose risks, especially for women. A new analysis of national data led by UC San Francisco found that older women who were broadly engaged in social activities before the COVID pandemic had 76 percent higher odds of experiencing emotional abuse or mistreatment than women who were less engaged. The paper is published June 9, 2021 in the Journal of the American Geriatrics Society. "Given widespread discussion about the negative effects of social isolation of ...

Research from the University of Washington shows that endangered blue whales are present and singing off the southwest coast of India. The results suggest that conservation measures should include this region, which is considering expanding tourism. Analysis of recordings from late 2018 to early 2020 in Lakshadweep, an archipelago of 36 low-lying islands west of the Indian state of Kerala, detected whales with a peak activity in April and May. The study was published in May in the journal Marine Mammal Science. "The presence of blue whales in Indian waters is well known from several strandings and some live sightings of blue whales," said lead author Divya Panicker, a ...

A new study conducted by the researchers at the University of Liverpool reveals how the ancient photosynthetic organisms - cyanobacteria - evolve their photosynthetic machinery and organise their photosynthetic membrane architecture for the efficient capture of solar light and energy transduction. Oxygenic photosynthesis, carried out by plants, algae, and cyanobacteria, produces energy and oxygen for life on Earth and is arguably the most important biological process. Cyanobacteria are among the earliest phototrophs that can perform oxygenic photosynthesis and make significant contributions to the Earth's atmosphere and primary production. Light-dependent photosynthetic reactions are performed by a set of photosynthetic ...

Laser-produced high energy density plasmas, akin to those found in stars, nuclear explosions, and the core of giant planets, may be the most extreme state of matter created on Earth. Now scientists at the U.S. Department of Energy's (DOE) Princeton Plasma Physics Laboratory (PPPL), building on nearly a decade of collaboration with the National Ignition Facility (NIF) at the DOE's Lawrence Livermore National Laboratory (LLNL), have designed a novel X-ray crystal spectrometer to provide high-resolution measurements of a challenging feature of NIF-produced HED plasmas. Most powerful lasers The ...

An international research team led by members from the Technical University of Munich, the Deutsches Museum, Munich, and the Swedish Linköping University has developed a method to manufacture two-dimensional polymers with the thickness of a single molecule. The polymers are formed on a surface by the action of light. The discovery paves the way to new ultrathin and functional materials. The quest for new two-dimensional materials has rapidly intensified after the discovery of graphene - a supermaterial whose excellent properties include high conductivity and strength, making it incredibly versatile. Two main ...

WASHINGTON -- In a new study, researchers demonstrate an automated, easy-to-operate quantum key distribution (QKD) system using the fiber network in the city of Padua, Italy. The field test represents an important step toward implementing this highly secure quantum communication technology using the type of communication networks already in place in many regions around the world. QKD offers impenetrable encryption for data communication because it uses the quantum properties of light to generate secure random keys for encrypting and decrypting data. "QKD can be useful in any situation where security is paramount because it offers unconditional security for the key exchange process," ...

Two gene variants found in African American women may explain why they are more likely to be diagnosed with triple negative breast cancer (TNBC) than white women of European ancestry, according to Weill Cornell Medicine and NewYork-Presbyterian investigators. The study findings may have implications for developing better risk assessment tools for TNBC in African American women and for understanding why they have poorer TNBC outcomes. In a study, published April 29 in Scientific Reports, the investigators found that a version of the ANKLE1 gene that can be protective against TNBC is less likely to be found in African American women than white women of European ancestry. In addition, African American women with a mutation in the Duffy gene, which plays a role in inflammation, ...

Inside each proton or neutron there are three quarks bound by gluons. Until now, it has often been assumed that two of them form a "stable" pair known as a diquark. It seems, however, that it's the end of the road for the diquarks in physics. This is one of the conclusions of the new model of proton-proton or proton-nucleus collisions, which takes into account the interactions of gluons with the sea of virtual quarks and antiquarks. In physics, the emergence of a new theoretical model often augurs badly for old concepts. This is also the case with the description of collisions of protons with protons or atomic nuclei, proposed by scientists from the Institute of Nuclear Physics of the Polish Academy of Sciences (IFJ PAN) ...

Organic residues on ceramic pottery are a valuable resource for understanding medieval cuisines of Islamic-ruled Sicily, according to a study published June 9, 2021 in the open-access journal PLOS ONE by Jasmine Lundy of the University of York, UK and colleagues. During the 9th to 12th century AD, Sicily was under Islamic rule. This transition is known to have profoundly impacted the region, and the capital city of Palermo thrived as an economic and cultural center of the Mediterranean Islamic world. But little is known about how the lives of people in the region were impacted during this important time period. In this study, researchers examined organic residues of plant and animal products on ceramic pottery to gain insights ...

Today, solar energy provides 2% of U.S. power. However, by 2050, renewables are predicted to be the most used energy source (surpassing petroleum and other liquids, natural gas, and coal) and solar will overtake wind as the leading source of renewable power. To reach that point, and to make solar power more affordable, solar technologies still require a number of breakthroughs. One is the ability to more efficiently transform photons of light from the Sun into useable energy.Organic photovoltaics max out at 15% to 20% efficiency -- substantial, but a limit on solar energy's potential. Lehigh University engineer Ganesh Balasubramanian, like many others, wondered if there were ways to improve the design of solar cells to make them more ...

GRAND RAPIDS, Mich. (JUNE 8, 2021) -- Chronic inflammation in the gut may propel processes in the body that give rise to Parkinson's disease, according to a study by scientists at Van Andel Institute and Roche. The study, published in Free Neuropathology, is the latest in a growing list that links the gut and the immune system to Parkinson's. The researchers' findings in an experimental mouse model of gut inflammation track with several large-scale epidemiological studies that show an association between Parkinson's and inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease. Epidemiological evidence from other groups indicates the risk of developing Parkinson's fades in certain people whose ...