DALLAS, Feb. 24, 2021 -- Postmenopausal women who ate high levels of plant protein had lower risks of premature death, cardiovascular disease and dementia-related death compared with women who ate less plant proteins, according to new research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association. Previous research has shown an association between diets high in red meat and cardiovascular disease risk, yet the data is sparse and inconclusive about specific types of proteins, the study authors ...

In the largest genome-wide association study of glaucoma comparing the genes of 34,179 people with the disease to 349,321 control subjects, an international consortium of researchers identified 44 new gene loci and confirmed 83 previously reported loci linked to glaucoma. Loci are considered "genetic street addresses," denoting a specific location on a gene. The study's authors hope the identification of these genes will lead to new treatment targets for this incurable eye disease that is a leading cause of blindness worldwide. "These new findings come out of the highest-powered genome-wide association study of glaucoma to date, and show the power of team science and using big data to answer questions when research groups around the world join forces," said co-senior study author ...

Peer review/Experimental study/Cells Researchers at Uppsala University have created the first 3D map of the hearing nerve showing where the various sound frequencies are captured. Using what is known as synchrotron X-ray imaging, they were able to trace the fine nerve threads and the vibrating auditory organ, the cochlea, and find out exactly how the frequencies of incoming sound are distributed. The study is published in Scientific Reports. "This can make treatment with cochlea implants for the hearing-impaired more effective," says Helge Rask-Andersen, Professor of Experimental Otology at Uppsala ...

Genome variation data on more than 7,000 malaria parasites from 28 endemic countries is released today (24 February) in Wellcome Open Research. It has been produced by MalariaGEN, a data-sharing network of groups around the world who are working together to build high-quality data resources for malaria research and disease control. This open data release represents the world's largest resource of genomic data on malaria parasite evolution and drug resistance. It provides benchmark data on parasite genome variation that is needed in the search for new drugs and vaccines, and in the development of surveillance tools for malaria control and elimination. Malaria is a major global ...

In the journal Nature Communications, scientists of the German Center for Neurodegenerative Diseases (DZNE) report new findings on the mechanisms of "Niemann-Pick type C disease" (NPC). This rare brain disorder mainly manifests in childhood and includes severe neurological and psychiatric symptoms. Researchers led by Dr. Sabina Tahirovic have now found evidence that already at an early stage, NPC is associated with neuroinflammation and that this condition is triggered by impaired intracellular lipid transport. In addition, they identified pathological features in the blood of affected individuals that in the future could assist to better monitor the course of the disease and response to therapy. NPC is a hereditary metabolic disorder ...

New research has found one in five people in the south London live with multimorbidity. The study, published today in the Lancet Regional Health by researchers from King's College London and the NIHR Guy's and St Thomas' Biomedical Research Centre and supported by Impact on Urban Health, examined the prevalence of multimorbidity - two or more long-term diseases at once - and identified key relationships between diseases. Researchers analysed electronic health records from participants aged 18 and over between April 2005 and May 2020 in one London borough. The borough has a deprived, ...

PHILADELPHIA - A machine learning-based tool was able to predict the risk of malignancy among patients presenting with multiple pulmonary nodules and outperformed human experts, previously validated mathematical models, and a previously established artificial intelligence tool, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research. Tools currently available can predict malignancy in patients with single nodules; predictive tools for patients presenting with multiple nodules are limited. "With the adoption of widespread use of thoracic computed tomography (CT) for lung cancer screening, the detection of multiple pulmonary nodules has become increasingly ...

SILVER SPRING, Md.--A systematic review of multiple randomized controlled studies among adults with overweight or obesity showed that greater engagement in self-monitoring using digital health tools was associated with significant weight loss, according to a paper published online in Obesity, The Obesity Society's flagship journal. This is the first comprehensive systematic review to examine the relationship between digital self-monitoring and weight loss. "Digital health tools have flourished in the past decade," said Michele L. Patel, PhD, post-doctoral ...

Do you dim the lighting and turn on the red light for a romantic night in with your partner? It turns out moths aren't so different in that regard. A new study published in END ...

Mangrove forests with greater species diversity can store more carbon, according to new research published in the British Ecological Society journal Functional Ecology. Researchers studying mangrove forests in Hainan Island, China, have found that species diversity in mangrove forests enhances both biomass production (the quantity of organic matter) and soil carbon storage. The findings highlight the impotence of conserving mangrove biodiversity as a nature-based solution to mitigate climate change. The East side of the island was found to have the highest mangrove biomass, diversity and carbon storage, with a mean of 537 tonnes of carbon per hectare (Mg C ha-1). ...

CLEVELAND, Ohio (Feb 24, 2021)--The aging population combined with increasing obesity rates has resulted in more women experiencing pelvic organ prolapse. Common treatment options include pelvic reconstructive surgery or the use of pessaries to prop up descending organs. A new study evaluated the long-term effectiveness of pessaries, as well as reasons why women discontinued their use. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS). Despite the fact that vaginal pessaries have existed in some form for thousands of years to help treat pelvic organ prolapse, few studies have been published regarding their long-term use and effectiveness. Pessaries are devices inserted into the vagina ...

Organic molecules that capture photons and convert these into electricity have important applications for producing green energy. Light-harvesting complexes need two semiconductors, an electron donor and an acceptor. How well they work is measured by their quantum efficiency, the rate by which photons are converted into electron-hole pairs. Quantum efficiency is lower than optimal if there is "self-quenching", where one molecule excited by an incoming photon donates some of its energy to an identical non-excited molecule, yielding two molecules at an intermediate energy state too low ...

BINGHAMTON, NY -- Ancestry estimation -- a method used by forensic anthropologists to determine ancestral origin by analyzing bone structures -- is rooted in "race science" and perpetuates white supremacy, according to a new paper by a forensic anthropologist at Binghamton University, State University of New York. By themselves, bones seem somewhat uniform to the untrained eye. They lack the traits we so often use to categorize fellow humans: hair texture, the shape of nose and eye, skin pigmentation. Forensic anthropologists know that race isn't based in biological fact, but in a history and culture that assigns meaning to physical traits that occur among different ...

Carbon nanotubes are tiny. They can be a hundred thousand times smaller than the width of a human hair. But they have huge potential. Products manufactured using carbon nanotubes include rebar for concrete, sporting goods, wind turbines, and lithium batteries, among others. Potential uses of carbon nanotubes could extend to diverse fields, such as agriculture, biomedicine and space science. But as we use more carbon nanotubes to make things, we also increase the chances that these nanotubes enter different environments and ecosystems. "That makes it important to understand how ...

February 24, 2021 - The second study published in as many months has identified another reason to add more mushrooms to the recommended American diet. The new research , published in Food & Nutrition Research (February 2021), examined the addition of mushrooms to U.S. Department of Agriculture (USDA) Food Patterns resulting in the increase of several micronutrients including shortfall nutrients, while having a minimal to zero impact on overall calories, sodium or saturated fat. Dr. Victor L. Fulgoni III and Dr. Sanjiv Agarwal looked at the nutritional ...

Small changes to people's writing style can reveal which social group they "belong to" at a given moment, new research shows. Groups are central to human identity, and most people are part of multiple groups based on shared interests or characteristics - ranging from local clubs to national identity. When one of these group memberships becomes relevant in a particular situation, behaviour tends to follow the norms of this group so that people behave "appropriately". The new study - by the University of Exeter, Imperial College London, University College London and Lancaster University - demonstrates that group normative behaviour is reflected in a person's writing style. It also shows that assessing ...

New research has highlighted the value of recycling general anaesthetic used in routine operations. In the UK, healthcare accounts for more than five per cent of national greenhouse gas emissions, and as much as 10 per cent in the US. Inhaled general anaesthetics are particularly potent greenhouse gases and as little is metabolised almost all that is administered is breathed out to end up in the atmosphere. The commonly used anaesthetic agents have been considered to vary considerably from as little as 1.5 for sevoflurane to more than 60 kg carbon dioxide equivalence for an hour's anaesthetic with desflurane. However, research led by a team from the University of ...

Researchers from University of British Columbia published a new paper in the Journal of Marketing that examines whether and how the use of 'ugly' labeling for unattractive produce increases sales and profit margins. The study, forthcoming in the Journal of Marketing, is titled "From Waste to Taste: How "Ugly" Labels Can Increase Purchase of Unattractive Produce" and is authored by Siddhanth (Sid) Mookerjee, Yann Cornil, and JoAndrea Hoegg. According to a recent report by the National Academies of Science, Engineering and Medicine (2020), each year in the U.S. farmers throw away up to 30% of their crops, equal to 66.5 million tons of edible produce, ...

WEST LAFAYETTE, Ind. - New technology from Purdue University and Indiana University School of Medicine innovators may one day help patients who suffer devastating vocal injuries from surgery on the larynx. A collaborative team consisting of Purdue biomedical engineers and clinicians from IU has tissue-engineered component tissue replacements that support reconstruction of the larynx. The team's work is published in The Laryngoscope. The larynx is a very complex human organ consisting of outer cartilage for structural support, inner muscle that contracts to permit voicing, swallowing, and breathing, and inner vibratory lining. Currently, thousands of patients each year with laryngeal cancer ...

RICHLAND, Wash. - No one went to Oktoberfest in 2020, but chances are those who attended in the past are still thinking about it. In a case study of the famous German beer festival, researchers tested the theory that events which create memorable experiences can increase life-satisfaction. This deep connection with customers has big benefits for associated businesses, according to Robert Harrington, lead author of the study recently published online in the International Journal of Contemporary Hospitality Management. "If you can do something that transforms people even a little bit, it can have a huge impact on the success of your company and your brand," said Harrington, professor and director of the School ...

A team of engineers has identified the 'violent' physical processes at work inside the lungs which cause wheezing, a condition which affects up to a quarter of the world's population. The researchers, from the University of Cambridge, used modelling and high-speed video techniques to show what causes wheezing and how to predict it. Their results could be used as the basis of a cheaper and faster diagnostic for lung disease that requires just a stethoscope and a microphone. Improved understanding of the physical mechanism responsible for generating wheezing sounds could provide a ...

A team of researchers concludes that a game-theory approach may offer new insights into both the spread and disruption of viruses, such as SARS-CoV-2. Its work, described in the journal Royal Society Interface, applies a "signaling game" to an analysis of cellular processes in illuminating molecular behavior. "We need new models and technologies at many levels in order to understand how to tame viral pandemics," explains Bud Mishra, a professor at NYU's Courant Institute of Mathematical Sciences and one of the paper's authors. "At the biomolecular level, we explain how cellularization may be understood in ways that stymie disease and encourage healthy functioning." The analysis, which also included William Casey, ...

A new study involving researchers from the University of Oxford and the Chinese Center for Disease Control and Prevention (China CDC) has examined the change in overall and cause-specific death rates during the three months of the COVID-19 outbreak in early 2020. The results are published today in The BMJ. In China, the emergence of COVID-19 was first reported during mid-December 2019 in Wuhan city, Hubei province. Coinciding with the January 2020 festivities for the Chinese Lunar New Year, the virus spread rapidly across China. This led to a national lockdown on 23 January 2020, which continued until early April. The ...

Night 'owls' may be twice as likely as morning 'larks' to underperform at work and to run a heightened risk of early retirement due to disability, finds research published online in the journal Occupational & Environmental Medicine. Given the move to lengthen working life and delay pension eligibility, it might be worth factoring in a person's chronotype, suggest the researchers. Morning chronotypes, or 'larks' tend to do better early in the morning, while evening chronotypes, or 'owls' do better in the evening. Chronotype is largely genetic, but environmental factors, such as exposure to daylight, work schedules, and family life can also influence it. Owls don't usually fall asleep early enough to get the recommended 7+ hours of sleep on ...

A whole foods, plant based diet may ease the painful skin blistering and scarring of a baffling blood vessel disorder for which there is as yet no commonly accepted cure, and no known cause, suggest doctors in the journal BMJ Case Reports. The primary symptoms of livedoid vasculopathy are extremely painful ulcers of varying sizes on the feet and lower legs, which leave visible scars when healed. The condition affects 1 in 100,000 people, mostly women in their 30s. The symptoms can last for months to years and can recur. Poor blood flow is often associated with the condition, but the exact cause remains a mystery, and there is as yet no commonly accepted cure, note the authors. They report the case of a woman in her early 60s, whose symptoms had first started in 2006. In 2013 ...