A study to examine recessively inherited genome-wide DNA sequences has for the first time discovered a potential link with Britain's biggest killer - Coronary Artery Disease (CAD). The research led by a team from the University of Leicester was the first time that recessively inherited DNA sequences in the whole genome called Runs of homozygosity (ROHs) were examined for a connection to the disease. The study appears in the American Journal of Human Genetics. CAD is a terminal clinical manifestation of cardiovascular disease and is the leading cause of death worldwide ...

Danish researchers are the first in the world to have used our genes to investigate the impact of coffee on the body. The new study shows that coffee neither increases nor decreases the risk of lifestyle diseases. We love coffee - and we drink a lot of it. New research from the University of Copenhagen and Herlev and Gentofte Hospital shows that coffee neither increases nor decreases the risk of developing lifestyle diseases such as obesity and diabetes. The researchers have based their study on genes, as our genes play a role in how much coffee we drink in the course ...

DENVER (July 9, 2015) - A new study from the University of Colorado Denver finds that male exotic dancers, or strippers, remain committed to stripping because it enhances their self-concept. The study by Maren Scull, an instructor of Sociology in the CU Denver College of Liberal Arts and Sciences, was published online this month in Deviant Behavior, the only scientific journal that specifically addresses behaviors that violate social norms. Scull's research focuses on how exotic dancing influences the way male strippers view themselves. "Because stripping is a stigmatizing ...

This news release is available in French. Since the treatment has become available, HIV is often described as "undetectable" and the risk of transmission has been drastically reduced. However, the epidemic is still quite present in the lives of many gay and bisexual men... and in public spaces. This often overlooked dimension of the disease has been brought to light by Gabriel Girard of the University of Montreal's Public Health Research Institute (IRSPUM) - HIV is still alive in the city, especially in the Village, Montreal's gay district. "Urban traces are significant ...

WEST LAFAYETTE, Ind. -- A key set of immune cells that protect the body from infection would be lost without directions provided by vitamin A, according to a recent study. A team of researchers from Purdue University found retinoic acid, a metabolite that comes from digested vitamin A, is necessary for two of the three types of innate immune cells that reside in the intestine to find their proper place. "It is known that vitamin A deficiencies lead to increased susceptibility to disease and low concentrations of immune cells in the mucosal barrier that lines the intestines," ...

MADISON, Wis. -- A study authored by two University of Wisconsin-Madison graduate students indicates that while playing video games can improve mood, violent games may increase aggressive outcomes. The study, authored by James Alex Bonus and Alanna Peebles, graduate students in Communication Arts, and Karyn Riddle, assistant professor in the School of Journalism and Mass Communication, was published in June in the journal Computers in Human Behavior. The researchers looked at how video games may be used to manage emotions -- specifically, whether playing the games can ...

(Edmonton) Screening newborn babies who are in the neonatal intensive care unit (NICU) using a testing process called high-frequency tympanometry can help identify middle-ear problems earlier, according to newly published research from a local team of researchers. "If people cannot hear, we need to know if the problem is with the middle ear, inner ear or hearing nerve. Obviously, a baby cannot tell you, so in the clinic it's hard to know when they have hearing loss," explained Ming Zhang, an associate professor at the U of A's Department of Communication Sciences and ...

The relationship between mental and physical health is well established. But when mental and physical illnesses co-occur, patients' accounts of physical illness are sometimes arbitrarily discredited or dismissed by physicians. Research by Jeremy D. Coplan, MD, professor of psychiatry at SUNY Downstate Medical Center, and colleagues has documented a high rate of association between panic disorder and four domains of physical illness. The research could alter how physicians and psychiatrists view the boundaries within and between psychiatric and medical disorders. "Patients ...

Green buildings are indeed healthy buildings. So says Dr. Joseph Allen and fellow researchers of the Harvard T.H. Chan School of Public Health in the US. They conducted the first comprehensive review of studies that focused on green buildings and summarized the health benefits for the people who work and live in them. The review is published in Springer's journal Current Environmental Health Reports. The green building movement has taken off in the past 10 years. According to Leadership in Energy and Environmental Design (LEED®), which certifies green building standards, ...

In about one-sixth of the cases of male infertility, men do not make any measurable levels of sperm, a condition called azoospermia. New research led by University of Pennsylvania scientists suggests that mutations in an X chromosome gene called TEX11 are responsible for about 1 percent of azoospermia cases. The investigators also found that in mice bred to lack the gene, reintroducing the gene restores their fertility. Additional studies in mice revealed that a certain amount of the TEX11 protein expressed from the gene is needed for sperm to form. The protein plays ...

An expert panel convened by the International Society for Sexual Medicine has developed a detailed "Process of Care" for the diagnosis and management of testosterone deficiency in men. After an extensive literature review and in-depth consultations, the panel of 18 experts from a wide range of medical disciplines recommended that testosterone deficiency be defined as a clinical and biochemical syndrome characterized by both a deficiency of testosterone or testosterone action, and relevant symptoms. The panel stressed that the condition may affect multiple organ systems ...

For the first time, a new analysis shows an impact of climate change on human society long before we knew the climate was actually changing. Exploring Google's scanned book collection, the analysis finds that society in general increasingly discussed some of the predicted effects of climate change--such as heat waves, drought, and flooding--long before current global weather alterations were widely known about. The authors note that while the science of climate change and climate action has come under sustained political attack, buttressing the physical record with ...

A related package of articles published online by JAMA Oncology focuses on end-of-life care for teens and young adults and advance care planning for patients with cancer. The package of articles includes two original investigations, an invited commentary, an editorial, an accompanying editor's note and an author audio interview. End-of-Life Care for Teens, Young Adults with Cancer In the first study, corresponding author Jennifer W. Mack, M.D., M.P.H., of the Dana-Farber Cancer Institute, Boston, and her coauthors looked at the intensity of end-of-life care for teens ...

In a review of nearly 2,000 surveys with people whose loved ones died of cancer, researchers led by Johns Hopkins experts say they found a 40 percent increase over a 12-year period in the number of patients with cancer who participated in one form of advance care planning -- designating durable power of attorney privileges to a loved one -- but no corresponding impact on their rates of aggressive medical care received in the last weeks of life. In addition, the investigators say that despite the substantial increase in patients who designated a durable power of attorney, ...

Adenoviruses cause numerous diseases, such as eye or respiratory infections, and they are widely used in gene therapy. Researchers from the University of Zurich have now discovered how these viruses penetrate the cells, a key step for infection and gene delivery The cell unwillingly supports virus entry and infection by providing lipids that are normally used to repair damaged membranes. An intact cell membrane is essential for any cell to function. The external cell membrane can be damaged by mechanical stress, for example in muscle cells, or by pathogens, such as ...

(Philadelphia, PA) - The buildup of fat in the blood makes a bad situation worse - it not only raises a person's risk for heart attack or stroke but also impairs the growth of new blood vessels. How excess fat in the blood - a condition known as hyperlipidemia - blocks vessel growth was unclear, but new work by researchers at Temple University School of Medicine (TUSM) shows that a molecule known as caspase-1 plays a central role and that preventing its activity could be the key to building new blood vessels and restoring blood supply to oxygen-starved tissues. "Caspase-1 ...

NOAA and its research partners, using an ensemble modeling approach, predict that the 2015 western Lake Erie harmful algal bloom season will be among the most severe in recent years and could become the second most severe behind the record-setting 2011 bloom. The effects of the cyanobacterial blooms include a higher cost for cities and local governments to treat their drinking water, as well as risk to swimmers in high concentration areas, and a nuisance to boaters when blooms form. These effects will vary in locations and severity with winds, and will peak in September. The ...

A group of preschoolers were given one shot to beat the world's fastest builder of block towers. Unbeknownst to the children, it had already been decided who would capture the victory and who would see it slip away. The losers shook it off without it ruining their mood. The winners - even the two-year-olds - showed some obvious swagger: heads held high, chests puffed out, hands on hips in a victorious power pose. But here's the thing - children show emotions much younger than they understand them. That's why the psychologists who staged the contest asked the ...

Research with human tissue and cells suggests that genetic variations, in addition to failure to comply with treatment regimens, may account for some failures of an anti-HIV drug to treat and prevent HIV infection. In a report described online today in the journal EBioMedicine, investigators at Johns Hopkins found that tenofovir, marketed as Viread, is processed differently according to cell location, so that if the drug is eventually marketed as a topical gel, it could work differently depending on whether it is applied to the vagina or the rectum. Tenofovir has been ...

This news release is available in French. Montreal, July 9, 2015 -- Death rates due to health problems like obesity, type 2 diabetes, hypertension, and heart disease are on the rise. According to the World Health Organization, that's due to our increasingly sedentary lifestyles. Clearly, it's important to lead more active lives. Something as simple as taking the stairs can make a big difference. But can pedestrians be convinced to make healthy choices when an escalator seems so much faster and more convenient than a staircase? Yes, say researchers from Concordia ...

Around 85% of the matter in the Universe is dark [1], and of a type not understood by physicists. Although it doesn't shine or absorb light, astronomers can detect this dark matter through its effect on stars and galaxies, specifically from its gravitational pull. A major project using ESO's powerful survey telescopes is now showing more clearly than ever before the relationships between this mysterious dark matter and the shining galaxies that we can observe directly [2]. The project, known as the Kilo-Degree Survey (KiDS - http://kids.strw.leidenuniv.nl/), uses imaging ...

Childhood high blood pressure (HBP) is a serious public health challenge worldwide due to associated increases in risk of end organ damages and correlation with HBP in adulthood. The prevalence of elevated blood pressure (BP) has been reported to increase significantly among United States children and adolescents from 1988-1994 to 1999-2008, but little is known about recent trends in BP values and elevated BP. The authors of a new study, "Trends in elevated blood pressure among US children and adolescents: 1999-2012," published today by the American Journal of Hypertension, ...

ANN ARBOR--University of Michigan researchers and their colleagues predict that the 2015 western Lake Erie harmful algal bloom season will be among the most severe in recent years and could become the second-most severe behind the record-setting 2011 bloom. The 2015 seasonal forecast uses models that translate spring nutrient loading into predicted algal blooms in the Western Basin of Lake Erie. After a relatively dry April and May, the heavy rains in June produced record discharge and nutrient loadings from the Maumee River, which runs through Toledo and northeastern ...

This news release is available in German. Graphene, the only one atom thick carbon network, achieved overnight fame with the 2010 Nobel Prize. But now comes competition: Such layers can also be formed by black phosphorous. Chemists at the Technische Universität München (TUM) have now developed a semiconducting material in which individual phosphorus atoms are replaced by arsenic. In a collaborative international effort, American colleagues have built the first field-effect transistors from the new material. For many decades silicon has formed the ...

Chicago - Although opioids are frequently prescribed to treat chronic lower back pain, new research suggests these powerful medications may be less effective in some patients. A study published in the Online First edition of Anesthesiology, the official medical journal of the American Society of Anesthesiologists® (ASA®), found patients who were prescribed opioids to treat chronic lower back pain experienced significantly less pain relief and were more likely to abuse their medication when they had psychiatric disorders such as depression or anxiety. "High levels ...