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University study highlights alarming rise in usage and costs of antidepressants

University study highlights alarming rise in usage and costs of antidepressants
2021-06-03
RESEARCHERS at the University of Huddersfield have warned there is an urgent need for the country's mental health interventions to create strategies optimising the use of antidepressants after conducting a study which has highlighted an alarming rise in relation to usage and costs. The open-access study, published by the international DARU Journal of Pharmaceutical Sciences, is entitled 'Surging trends in prescriptions and costs of antidepressants in England amid COVID-19' and has investigated the trends in prescriptions and costs of various antidepressants in England during the COVID-19 pandemic. The researchers discovered that the total number of antidepressant prescriptions drugs dispensed during ...

A better way to introduce digital tech in the workplace

2021-06-03
When bringing technologies into the workplace, it pays to be realistic. Often, for instance, bringing new digital technology into an organization does not radically improve a firm's operations. Despite high-level planning, a more frequent result is the messy process of frontline employees figuring out how they can get tech tools to help them to some degree. That task can easily fall on overburdened workers who have to grapple with getting things done, but don't always have much voice in an organization. So isn't there a way to think systematically about implementing digital technology in the workplace? MIT Professor Kate Kellogg thinks there is, and calls it "experimentalist governance of digital technology": Let different parts of an organization experiment with the technology -- ...

Life stage differences shield ecological communities from collapse

2021-06-03
A new study by ecologist André de Roos* shows that differences between juveniles and adults of the same species are crucial for the stability of complex ecological communities. The research, published in Proceedings of the National Academy of Sciences, represents a major advance in ecological modeling at a time when biodiversity is declining and species around the world are rapidly going extinct. Up to now, ecological models have focused exclusively on the interactions between species, ignoring the variations within them. The dragonflies, frogs, trout, and phytoplankton in a freshwater pond, for example, would be represented as nodes in a network, connected by edges that ...

Study finds age doesn't affect perception of 'speech-to-song illusion'

2021-06-03
LAWRENCE -- A strange thing sometimes happens when we listen to a spoken phrase again and again: It begins to sound like a song. This phenomenon, called the "speech-to-song illusion," can offer a window into how the mind operates and give insight into conditions that affect people's ability to communicate, like aphasia and aging people's decreased ability to recall words. Now, researchers from the University of Kansas have published a study in PLOS ONE examining if the speech-to-song illusion happens in adults who are 55 or older as powerfully as it does with younger ...

Researchers discover potential new approach to treating psoriatic joint inflammation

2021-06-03
(SACRAMENTO, Calif.) - An international team of researchers, led by END ...

COVID-19: Seroprevalence and vaccine responses in UK dental care professionals

2021-06-03
Alexandria, Va., USA -- Dental care professionals are thought to be at enhanced risk of occupational exposure to SARS-CoV-2, but robust data to support this is lacking. The study "COVID-19: Seroprevalence and Vaccine Responses in UK Dental Care Professionals," published in the Journal of Dental Research (JDR), provides a longitudinal analysis of antibodies to SARS-CoV-2 spike glycoprotein, including early analysis of the impact of vaccination on the immune response. In June 2020, I,507 West Midlands dental care professionals were recruited to test for baseline seroprevalence, or the proportion of the population that have circulating antibodies to SARS-CoV-2, indicating prior ...

Filter membrane renders viruses harmless

2021-06-03
Viruses can spread not only via droplets or aerosols like the new coronavirus, but in water, too. In fact, some potentially dangerous pathogens of gastrointestinal diseases are water-borne viruses. To date, such viruses have been removed from water using nanofiltration or reverse osmosis, but at high cost and severe impact on the environment. For example, nanofilters for viruses are made of petroleum-based raw materials, while reverse osmosis requires a relatively large amount of energy. Environmentally friendly membrane developed Now an international team of researchers led by Raffaele ...

You're more likely to fight misinformation if you think others are being duped

2021-06-03
People in both the United States and China who think others are being duped by online misinformation about COVID-19 are also more likely to support corporate and political efforts to address that misinformation, according to a new study. The study suggests negative emotions may also play a role in the U.S. - but not in China. "A lot of misinformation has been shared online over the course of the COVID-19 pandemic, and we had a range of questions about how people are responding to this misinformation," says Yang Cheng, co-lead author of the study and an assistant professor of communication at North Carolina State University. "How do different emotions influence ...

Wearable accelerometer and vibrator 'thimble' could reduce falls amongst seniors

Wearable accelerometer and vibrator 'thimble' could reduce falls amongst seniors
2021-06-03
Japanese researchers have developed and tested a prototype device -- wearable on the fingertips -- that incorporates the concept of 'light touch' to enhance the sense of balance. If widely implemented, the device should significantly reduce incidence of falls amongst seniors. The findings are published in the journal Scientific Reports on April 1. As we age, our sense of balance can become impaired. The resulting increase in postural sway in turn increases the risk of falls and consequent injuries. Meanwhile, older people make up a large and increasing proportion of the population in highly developed countries. ...

The DNA of three aurochs found next to the Elba shepherdess opens up a new enigma for palaeontology

The DNA of three aurochs found next to the Elba shepherdess opens up a new enigma for palaeontology
2021-06-03
Research involving scientists from the University of A Coruña has succeeded in sequencing the oldest mitochondrial genome of the immediate ancestor of modern cows that has been analysed to date. The remains, some 9,000 years old, were found next to a woman. Why were they with her if cattle had not yet been domesticated? Do they belong to ancestors of today's Iberian cows? Humans have maintained a very close relationship with aurochs (Bos primigenius) since their beginnings, first by hunting them and then by breeding and selecting them. This extinct species of mammal is little known in the Peninsula because its skeletal remains are difficult to distinguish from bison. In fact, there have been references to the presence of "large bovids" in many sites because ...

Tipping elements can destabilize each other, leading to climate domino effects

2021-06-03
Interactions in the network can lower the critical temperature thresholds beyond which individual tipping elements begin destabilizing on the long-run, according to the study - the risk already increases significantly for warming of 1.5°C to 2°C, hence within the temperature range of the Paris Agreement. "We provide a risk analysis, not a prediction, yet our findings still raise concern," says Ricarda Winkelmann, Lead of FutureLab on Earth Resilience in the Anthropocene at the Potsdam Institute for Climate Impact Research (PIK). "We find that the interaction of these four tipping elements can make them overall more vulnerable due to mutual destabilization on the long-run. The feedbacks between them tend to lower the critical temperature ...

Role of women highlighted in study focused on the benefits of good farmer seed production

Role of women highlighted in study focused on the benefits of good farmer seed production
2021-06-03
A new study looking at the benefits of good farmer seed production suggests women need more support to participate in contract farming - to the same extent as their male counterparts - and have more equality along the whole food value chain. The CABI-led research - which sought to assess the benefits of good farmer seed production through a case study of the Good Seed Initiative in Tanzania - reveals that while around 70% of the labour to grow African Indigenous Vegetables (AIVs) is provided by women only 10 to 30% are contract farmers who own the fields, make decisions on sales and control revenues. The paper, led by Dr Monica Kansiime ...

Big data helps assess seizure burden, improve outcomes in pediatric epilepsy patients

2021-06-03
Philadelphia, June 3, 2021 - Researchers at Children's Hospital of Philadelphia (CHOP) have demonstrated how to use standardized reporting of clinical data for seizures caused by a variety of neurological disorders, providing fundamental baseline information that can determine what methods work best for keeping seizures under control. The findings were published today in the journal Epilepsia. In order to make improvements in epilepsy care, clinicians need a reliable and efficient method to measure outcomes. While Electronic Medical Records (EMR) are being used more frequently for research and quality improvement, important epilepsy outcome measures such ...

Aging impairs anti-tumor T-cell response via mitochondria dysfunction

Aging impairs anti-tumor T-cell response via mitochondria dysfunction
2021-06-03
MUSC Hollings Cancer Center researchers are finding solutions to the aging-related changes that reduce anti-cancer immunity. Besim Ogretmen, Ph.D., and colleagues found a novel link between aging, metabolism and anti-cancer T-cell function. Their work, published in Cell Reports, sheds light on an important pathway that cannot be ignored during cancer treatment. Two broad questions in cancer research are: How can cancer treatments be improved, and what is the link between cancer and aging? "We know that the protective T-cell response deteriorates with age. Mitochondrial function is now thought to be one of the central regulators of the aging process. Our experiments connected the dots with what was previously shown and highlighted some ...

Study shows obesity may increase risk of long-term complications of COVID-19

2021-06-03
Thursday, June 3, 2021, CLEVELAND: A Cleveland Clinic study shows that survivors of COVID-19 who have moderate or severe obesity may have a greater risk of experiencing long-term consequences of the disease, compared with patients who do not have obesity. The study was recently published online in the journal of Diabetes, Obesity and Metabolism. Multiple studies have identified obesity as a risk factor for developing a severe form of COVID-19 that may require hospital admission, intensive care, and ventilator support in the early phase of the disease. Obesity, which is a complex disease caused by multiple factors, is associated with an increased risk for cardiovascular ...

UNH research: Black bears may play important role in protecting gray fox

2021-06-03
DURHAM, N.H.-- Bears are known for being devoted and protective of their baby cubs, but research from the University of New Hampshire shows that they may also play a significant role in shielding gray fox from predators like coyotes, who compete with the fox for food and space. The research is one of the first studies to show how black bears provide a buffer to allow other, smaller carnivores to safely co-exist. "Even though black bears and coyotes are the two most common carnivores in North America, we're still learning how they affect the ecosystems around them," said Rem Moll, assistant professor of wildlife ecology and lead author ...

The biodegradable battery

The biodegradable battery
2021-06-03
The fabrication device for the battery revolution looks quite unconspicuous: It is a modified, commercially available 3D printer, located in a room in the Empa laboratory building. But the real innovation lies within the recipe for the gelatinous inks this printer can dispense onto a surface. The mixture in question consists of cellulose nanofibers and cellulose nanocrystallites, plus carbon in the form of carbon black, graphite and activated carbon. To liquefy all this, the researchers use glycerin, water and two different types of alcohol. Plus a pinch of table salt for ionic conductivity. A sandwich of four layers To build a functioning supercapacitor from these ingredients, four layers are needed, all flowing out of the 3D printer one after the ...

Enantiomorph distribution maps for metals and metallic alloys

Enantiomorph distribution maps for metals and metallic alloys
2021-06-03
Left- or right-handedness is a symmetry property that many macroscopic objects also exhibit and which is of immense importance, particularly for the bioactivity of organic molecules. Chirality is also relevant for physical or chemical properties such as optical activity or enantioselectivity of crystalline solids or their surfaces. In the case of chiral metallic phases, unconventional superconductivity and unusual magnetic ordered states are linked to the chirality of the underly-ing crystal structure. Despite this connection between chirality and the properties of a material, detection is often difficult because left-handed and righthanded ...

Are wind farms slowing each other down?

Are wind farms slowing each other down?
2021-06-03
The expansion of wind energy in the German Bight and the Baltic Sea has accelerated enormously in recent years. The first systems went into operation in 2008. Today, wind turbines with an output of around 8,000 megawatts rotate in German waters, which corresponds to around eight nuclear power plants. But space is limited. For this reason, wind farms are sometimes built very close to one another. A team led by Dr. Naveed Akhtar from Helmholtz Zentrum Hereon has found that wind speeds at the downstream windfarm are significantly slowed down. As the researchers now write in the journal Nature Scientific Reports, this braking effect results in astonishingly large-scale low wind pattern noticeable in mean ...

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

2021-06-03
Neurodegenerative disorders that cause dementia increase the risk of contracting severe COVID-19 and dying from the disease. For people with Alzheimer's the risk is three times greater. It can be six times greater if they are over 80, according to a study conducted in Brazil by researchers at the University of São Paulo (USP) and Butantan Institute in partnership with colleagues at the Federal University of Rio de Janeiro (UFRJ). An article on the study, which was supported by FAPESP, is published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association. "We found that all causes of dementia are risk factors for severity and death in COVID-19 and that these ...

Nanoscale sensors measure elusive water levels in leaves

Nanoscale sensors measure elusive water levels in leaves
2021-06-03
ITHACA, N.Y. - Water regulation in leaves is vital to a plant's health, affecting its growth and yield, disease susceptibility and drought resistance. A breakthrough technology developed by Cornell University researchers uses nanoscale sensors and fiber optics to measure water status just inside a leaf's surface, where water in plants is most actively managed. The engineering feat provides a minimally invasive research tool that will greatly advance the understanding of basic plant biology, and opens the door for breeding more drought-resistant crops. The technology could eventually be adapted for use as an agronomic tool for measuring water status in crops in real time. The study in maize plants, "A Minimally Disruptive Method for Measuring Water Potential In-Planta ...

Using advanced imaging to study sickle cell disease

Using advanced imaging to study sickle cell disease
2021-06-03
Sickle Cell Disease (SCD) is a genetically inherited group of red blood cell disorders. END ...

Researchers reveal the inner workings of a viral DNA-packaging motor

Researchers reveal the inner workings of a viral DNA-packaging motor
2021-06-03
DURHAM, N.C. - A group of researchers have discovered the detailed inner workings of the molecular motor that packages genetic material into double-stranded DNA viruses. The advance provides insight into a critical step in the reproduction cycle of viruses such as pox- herpes- and adeno-viruses. It could also give inspiration to researchers creating microscopic machines based on naturally occurring biomotors. The research was conducted by scientists from Duke University, the University of Minnesota, the University of Massachusetts and the University of Texas Medical Branch (UTMB). The results appear online in a trilogy of papers published in Science Advances, ...

Fifty years of progress in women's health

2021-06-03
WHO: JoAnn Manson, MD, DrPH, Physician and Epidemiologist, Division of Preventive Medicine, Brigham and Women's Hospital; co-author of a new Perspective piece published in The New England Journal of Medicine (pdf attached) WHAT: Less than 50 years ago, a U.S. Supreme Court decision paved the way for women's use of contraception irrespective of marital status, and a year later, in 1973, the Court ruled in Roe v. Wade that women have a right to legalized abortion. In recent decades, clinical researchers and policymakers alike have made important strides ...

Let's talk about the elephant in the data

Let's talk about the elephant in the data
2021-06-03
You would not be surprised to see an elephant in the savanna or a plate in your kitchen. Based on your prior experiences and knowledge, you know that is where elephants and plates are often to be found. If you saw a mysterious object in your kitchen, how would you figure out what it was? You would rely on your expectations or prior knowledge. Should a computer approach the problem in the same way? The answer may surprise you. Cold Spring Harbor Laboratory Professor Partha Mitra described how he views problems like these in a "Perspective" in Nature Machine Intelligence. He hopes his insights will help researchers teach computers how to analyze complex systems more effectively. Mitra thinks it helps to understand the nature of knowledge. Mathematically speaking, many data scientists ...
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