Previous studies conducted in hospitals reported that COVID-19 patients presented with unusual skin rashes. This study, which is published in the British Journal of Dermatology, analyzed information provided by 336,847 individuals in the community who used the COVID Symptom Study app. Skin rashes were more common in adults with a positive COVID-19 test result than in those who tested negative. Strikingly, among respondents of an online survey, 17% of SARS-CoV-2-positive cases reported skin rashes as the first presentation, and 21% as the only COVID-19 clinical sign. Together with the British Association of Dermatologists, the study's investigators compiled a catalogue of images of the most common skin ...

An atmosphere is what makes life on Earth's surface possible, regulating our climate and sheltering us from damaging cosmic rays. But although telescopes have counted a growing number of rocky planets, scientists had thought most of their atmospheres long lost. However, a new study by University of Chicago and Stanford University researchers suggests a mechanism whereby these planets could not only develop atmospheres full of water vapor, but keep them for long stretches. Published March 15 in the Astrophysical Journal Letters, the research expands our picture of planetary formation and could help direct the search for habitable worlds in other star systems. "Our model is saying that these ...

CABI has led the first study to explore the income and food security effects of the fall armyworm invasion on a country - revealing that in Zimbabwe smallholder maize-growing households blighted by the pest are 12% more likely to experience hunger. Dr Justice Tambo, lead researcher of the study published in Food and Energy Security, sought to investigate the impact of the fall armyworm (Spodoptera frugiperda) on household income and food security as well as the extent to which a control strategy can help mitigate the negative impacts of the pest. He, along with CABI colleagues from its centres in Kenya and Zambia as well as in collaboration with Zimbabwe's Ministry of Lands, Agriculture, Water and Rural Settlement, also found ...

More often than ever before, water available in rivers is at the mercy of climate change, international researchers collaborating on a worldwide study with Michigan State University have revealed. The finding could profoundly affect future water and food security around the world. Yadu Pokhrel, associate professor of civil and environmental engineering in the MSU College of Engineering and a co-author of the study, said climate is the key driver in the current changes to global river flow. "It's a noteworthy finding because as climate change impacts extreme flows, it could be worsening flooding or increasing water scarcity during dry seasons," Pokhrel explained. Details of the new ...

The NANOGrav Collaboration recently captured the first signs of very low-frequency gravitational waves. Prof. Pedro Schwaller and Wolfram Ratzinger analyzed the data and, in particular, considered the possibility of whether this may point towards new physics beyond the Standard Model. In an article published in the journal SciPost Physics, they report that the signal is consistent with both a phase transition in the early universe and the presence of a field of extremely light axion-like particles (ALPs). The latter are considered as promising candidates for dark matter. Gravitational waves open a window into ...

Researchers at the University of Gothenburg, Sweden, have now presented results that may change our basic view of how type 2 diabetes occurs. Their study indicates that free fatty acids (FFAs) in the blood trigger insulin release even at a normal blood-sugar level, without an overt uncompensated insulin resistance in fat cells. What is more, the researchers demonstrate the connection with obesity: the amount of FFAs largely depends on how many extra kilos of adipose tissue a person carries, but also on how the body adapt to the increased adiposity. Worldwide, extensive research is underway to clarify exactly what happens in the body as type 2 diabetes progresses, and why obesity is such a huge risk factor for the disease. For almost 50 years, ...

Researchers at the University of Illinois Chicago have discovered that heparanase, HPSE, a poorly understood protein, is a key regulator of cells' innate defense mechanisms. Innate defense responses are programmed cellular mechanisms that are triggered by various danger signals, which have been conserved in many species throughout evolution. These systems can be set into action by pathogens, such as viruses, bacteria and parasites, as well as by environmental toxins and dysfunctional cells that can accumulate in the body over time. A more thorough understanding ...

The U.S. criminal legal system has expanded at a rapid pace, even as crime rates have declined since the 1990s. As a result, individuals' interactions with and surveillance by law enforcement are now commonplace. But citizens experience different interactions, with people of color who live in impoverished urban communities having the most frequent encounters. A new study interviewed young Philadelphia men to determine their perceptions of and reactions to this phenomenon. Nearly all of the men of color said they stayed at home and avoided public spaces out of concern over the potential interactions with others that might draw police ...

UTICA, NY -- Brown fat, also known as brown adipose tissue (BAT), is a special type of fat that helps maintain body temperature. Importantly, brown fat is a biological fuel linked to metabolic rate and fat storage. In a recent publication, Dr. Zhiqiang Lin, Assistant Professor at the Masonic Medical Research Institute (MMRI) and senior author of the manuscript, successfully developed a new way to enrich isolation of brown fat cells for use in his biochemistry studies. "When faced with a scientific setback, we simply start tackling potential hurdles," said Dr. Lin. One of these was having a need to develop a better way to isolate these fat cells. BAT is comprised of multiple cell types, which makes it difficult to ...

Between 2015 and 2017, Seattle, Washington, became the first U.S. city to increase its hourly minimum wage to $15, more than double the federal minimum wage and 60 percent higher than Seattle's previous minimum wage. A new study examined the impact of this change on public safety. The study was motivated by the idea that since crime is sometimes the result of material deprivation, changes in the minimum wage might have implications for criminal activity: Boosting the minimum wage could raise workers' salaries (which could be associated with reduced crime). But if higher minimum wages spur employers to substitute capital for labor, this could ...

Increases in the use of telehealth during the coronavirus pandemic among people with private insurance has occurred mostly among those who are more affluent and those who live in metropolitan areas, according to a new RAND Corporation study. Researchers say the findings raise concerns that the pandemic may be worsening existing disparities in overall health care utilization. Overall, the study found there was a 20-fold increase in the rate of telemedicine utilization following the outset of the pandemic in March 2020. At the same time, the rate of office-based medical encounters declined by nearly 50% and was not fully offset by the increase in telemedicine. The findings are published online by the American Journal of Preventive ...

Robotics researchers are developing exoskeletons and prosthetic legs capable of thinking and making control decisions on their own using sophisticated artificial intelligence (AI) technology. The system combines computer vision and deep-learning AI to mimic how able-bodied people walk by seeing their surroundings and adjusting their movements. "We're giving robotic exoskeletons vision so they can control themselves," said Brokoslaw Laschowski, a PhD candidate in systems design engineering who leads a University of Waterloo research project called ExoNet. Exoskeletons ...

In the first all-sky survey by the eROSITA X-ray telescope onboard SRG, astronomers at the Max Planck Institute for Extraterrestrial Physics have identified a previously unknown supernova remnant, dubbed "Hoinga". The finding was confirmed in archival radio data and marks the first discovery of a joint Australian-eROSITA partnership established to explore our Galaxy using multiple wavelengths, from low-frequency radio waves to energetic X-rays. The Hoinga supernova remnant is very large and located far from the galactic plane - a surprising first finding - implying that the next years might bring many more ...

During pandemics, protective behaviors need to be motivated by effective communication. A critical factor in understanding a population's response to such a threat is the fear it elicits, since fear both contributes to motivating protective responses, but can also lead to panic-driven behaviors. Furthermore, lockdown measures affect well-being, making it important to identify protective factors that help to maintain high perceived levels of health during restrictions. An international team of researchers led by scientists from the University of Vienna has now identified psychological predictors of fear and health during the lockdowns. The result of the study, published in PLOS ONE: Individual psychological variables have a much better predictive power than environmental variables. The ...

We all have a clear picture in mind when we think of metals: We think of solid, unbreakable objects that conduct electricity and exhibit a typical metallic sheen. The behaviour of classical metals, for example their electrical conductivity, can be explained with well-known, well-tested physical theories. But there are also more exotic metallic compounds that pose riddles: Some alloys are hard and brittle, special metal oxides can be transparent. There are even materials right at the border between metal and insulator: tiny changes in chemical composition turn the metal into an insulator - or vice versa. ...

Cryoprotectants are used to protect biological material during frozen storage They have to be removed when defrosting, and how much to use and how exactly they inhibit ice recrystallisation is poorly understood The polymer poly(vinyl)alcohol (PVA) is arguably the most potent ice recrystallisation inhibitor and researchers from the University of Warwick have unravelled how exactly it works. This newly acquired knowledge base provides novel guidelines to design the next generation of cryoprotectants When biological material (cells, blood, tissues) is frozen, cryoprotectants are used to prevent the damage associated with the formation of ...

Researchers uncovered for the first time what happens in animals' brains when they learn from subconscious, visual stimuli. In time, this knowledge can lead to new treatments for a number of conditions. The study, a collaboration between KU Leuven, Massachusetts General Hospital, and Harvard was published in Neuron. An experienced birdwatcher recognises many more details in a bird's plumage than the ordinary person. Thanks to extensive training, he or she can identify specific features in the plumage. This learning process is not only dependent on conscious processes. Previous research has shown that when people are rewarded during the presentation of visual stimuli that are not consciously perceivable, ...

Researchers from Skoltech and the Massachusetts Institute of Technology have analyzed several dozen options to pick the best one in terms of performance and costs for the 'last mile' of a future mission to the Moon - actually delivering astronauts to the lunar surface and back up to the safety of the orbiting lunar station. The paper was published in the journal Acta Astronautica. Ever since December 1972, when the crew of Apollo 17 left the lunar surface, humans have been eager to return to the Moon. In 2017, the US government launched the Artemis program, which intends ...

An RCSI study conducted in Beaumont Hospital in Dublin has found that surgery, rather than antibiotics-only, should remain as the mainstay of treatment for acute uncomplicated appendicitis. Published in the Annals of Surgery and led by researchers from the RCSI University of Medicine and Health Sciences, the study entitled the COMMA trial (Conservative versus Open Management of Acute uncomplicated Appendicitis) examined the efficacy and quality of life associated with antibiotic-only treatment of acute uncomplicated appendicitis versus surgical intervention. The results revealed that antibiotic-only treatment resulted in high recurrence rates and an inferior quality ...

Drugs such as beta-adrenergic antagonists (beta blockers) have been linked to a range of adverse effects, including depression. But how reliable are these data, and which psychiatric side effects might indeed be caused by these drugs? These questions have been addressed by a team of researchers from Charité - Universitätsmedizin Berlin, whose comprehensive meta-analysis has been published in Hypertension*. While treatment with beta blockers was not found to be associated with an increased incidence of depression, some studies recorded higher levels of sleep disturbance. Beta-adrenergic ...

During the past decade the European People's Party in the European Parliament was criticized for its unwillingness to vote for measures that would sanction the Hungarian Fidesz government, which is accused of breaching key democratic principles. Researchers have said the EPP protected Fidesz in order to safeguard Hungarian votes in its ranks and protect their own interests, but this support had weakened by 2019, when Fidesz was suspended from the EPP. Researchers analysed the votes of EPP MEPs for 24 resolutions covering the protection of EU fundamental values ...

(Boston)-- Warning signs for Alzheimer's disease (AD) can begin in the brain years before the first symptoms appear. Spotting these clues may allow for lifestyle changes that could possibly delay the disease's destruction of the brain. "Improving the diagnostic accuracy of Alzheimer's disease is an important clinical goal. If we are able to increase the diagnostic accuracy of the models in ways that can leverage existing data such as MRI scans, then that can be hugely beneficial," explained corresponding author Vijaya B. Kolachalama, PhD, assistant professor of medicine at Boston University School ...

COLUMBUS, Ohio - An analysis of historic and projected simulations from 19 global climate models shows that, because of climate change, the temperature in the Antarctic peninsula will increase by 0.5 to 1.5 degrees Celsius by 2044. The projections also showed that precipitation - a threat to ice if it manifests as rain - will likely increase on the peninsula by about 5% to 10% over that same time period. The estimates were published recently in the journal Climate Dynamics. "We are concerned about these findings. We've been seeing overall quite big changes on the peninsula, generally getting warmer and ice shelves and glaciers discharging into the ocean," said David Bromwich, a leading author of the study and a research professor at The Ohio State University ...

PROVIDENCE, R.I. [Brown University] -- Proposals to create a national gun registry have long been met with fierce opposition from gun rights advocates. While proponents say a registry would help in tracking guns used in crimes, opponents worry that it would compromise privacy and could be used by the federal government to confiscate firearms. Now, a team of Brown University computer scientists has devised a way of implementing a registry that may allay some of those concerns. They propose a database that uses advanced encryption to protect privacy. The encryption scheme allows the database to be searched without being decrypted, which means people querying the database see only the records they're looking for and nothing else. Meanwhile, the system places control of data ...

Lemurs can use their sense of smell to locate fruit hidden more than 50 feet away in the forest--but only when the wind blows the fruit's aroma toward them, according to a study published in the American Journal of Physical Anthropology. "This is the first time research has demonstrated that primates can track a distant smell carried by the wind," said anthropologist Elena Cunningham, a clinical associate professor of molecular pathobiology at NYU College of Dentistry and the study's lead author. Many animals use their sense of smell to locate food. However, less is known about whether primates can smell food that is far away, or if they instead rely on visual cues or memory to find their next meal. Because many primates--including ring-tailed lemurs, ...