The St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project has identified mutations responsible for more than half of a subtype of childhood brain tumor that takes a high toll on patients. Researchers also found evidence the tumors are susceptible to drugs already in development. The study focused on a family of brain tumors known as low-grade gliomas (LGGs). These slow-growing cancers are found in about 700 children annually in the U.S., making them the most common childhood tumors of the brain and spinal cord. For patients whose ...

The extraordinary level of conservation of the tulip tree (Liriodendron tulipifera) mitochondrial genome has redefined our interpretation of evolution of the angiosperms (flowering plants), finds research in biomed Central's open access journal BMC Biology. This beautiful 'molecular fossil' has a remarkably slow mutation rate meaning that its mitochondrial genome has remained largely unchanged since the dinosaurs were roaming the earth. Evolutionary studies make used of mitochondrial (powerhouse) genomes to identify maternal lineages, for example the human mitochondrial ...

Researchers at Case Western Reserve School of Medicine have discovered a technique that directly converts skin cells to the type of brain cells destroyed in patients with multiple sclerosis, cerebral palsy and other so-called myelin disorders. This discovery appears today in the journal Nature Biotechnology. This breakthrough now enables "on demand" production of myelinating cells, which provide a vital sheath of insulation that protects neurons and enables the delivery of brain impulses to the rest of the body. In patients with multiple sclerosis (MS), cerebral palsy ...

A new chemical process can transform waste sulfur into a lightweight plastic that may improve batteries for electric cars, reports a University of Arizona-led team. The new plastic has other potential uses, including optical uses. The team has successfully used the new plastic to make lithium-sulfur batteries. "We've developed a new, simple and useful chemical process to convert sulfur into a useful plastic," lead researcher Jeffrey Pyun said. Next-generation lithium-sulfur, or Li-S, batteries will be better for electric and hybrid cars and for military uses because ...

It is unnecessary to scan trauma patients based on a non-focused standard trauma CT protocol, if the patient is transferred for care after already undergoing a focused CT examination based on the patient's history and physical examination, a new study shows. The study, conducted at the University of Pittsburgh Medical Center reviewed the records of 100 patients who were transferred from another facility. "The standard trauma CT protocol for all level 1 and 2 trauma patients transferred to our facility includes a CT examination of the head, cervical spine, thoracic spine, ...

Adding a photo of a face to x-ray images can reduce "wrong-patient" errors five-fold, a new study finds. "X-rays can look alike, and if one patient's images are confused with another before the radiologist sees them, it can be difficult for the radiologist to determine there is a mismatch," said Dr. Srini Tridandapani, of Emory University and an author of the study. As part of the study, ten radiologists interpreted 20 pairs of radiographic images with and without photographs. Two to four mismatched pairs were included in each set of 20 pairs of images. When photographs ...

High sugar levels in the body come at a cost to health. New research suggests that more sugar in the body could damage the elastic proteins that help us breathe and pump blood. The findings could have health implications for diabetics, who have high blood-glucose levels. Researchers at the University of Washington and Boston University have discovered that a certain type of protein found in organs that repeatedly stretch and retract – such as the heart and lungs – is the source for a favorable electrical property that could help build and support healthy connective tissues. ...

SAN DIEGO – (April 15, 2013) As efforts to create a strong and effective vaccine for the dreaded dengue virus continue to hit snags, a new study from researchers at the La Jolla Institute for Allergy & Immunology offers surprising evidence that suggests the need for a revamped approach to dengue vaccine design. The finding runs counter to current scientific understanding of the key cells that need to be induced to develop a successful dengue vaccine. La Jolla Institute scientist Alessandro Sette, Dr.Biol.Sci., and his team found that T cells, which are key disease-fighting ...

Long commute times and urban areas that leapfrog over open space make it harder for people to socialize, but cities that are decentralized are even worse, University of Utah researchers say in a study published online today in the Journal of Transport Geography. "We found that decentralization has 10 times the negative impact of fragmentation, and 20 times that of longer commute times," says Steven Farber, assistant professor of geography at the university. "For planners and policy makers concerned about making our cities more vibrant, it is clear that intensifying development ...

Polarion Software, creators of the world's fastest enterprise scale web-based Application Lifecycle Management (ALM) solution, and Vector Software, the leading provider of dynamic software testing solutions for embedded systems, today announced a strategic partnership to develop solutions that improve software Verification and Validation in regulated environments. Vector Software solutions provide development organizations the most complete and cost-effective approach to managing the complexities of testing safety- and business-critical software. Vector Software's VectorCAST ...

Parents interested in learning more about Montessori education are invited to a free open house, 10 a.m. to 1 p.m. Saturday, April 27 at the Montessori International School, 2401 E. Brown Road in Mesa. In addition to tours of the campusl and showcasing examples of the student's work, the school's AMI-certified Montessori instructors will explain the basics of Montessori education and why the curriculum has been so successful with children for more than 100 years. There will also be hands-on art and science activities for visiting children to enjoy. Montessori International ...

The DocSafe, a secure online storage solution for crucial documents, is pleased to introduce its Safes4Soldiers program for members of our armed forces and their families can receive a FREE lifetime membership for The DocSafe services as a thank you for protecting our freedoms. Active military members simply need to contact The DocSafe by May 31 receive their membership. When contacting The DocSafe, provide a copy of your DoD identification card (black out your DoD ID number) or email The DocSafe from your ".mil" account. "The DocSafe allows the participants ...

Self-published author S.P. Kaye has decided to leverage the popular crowdfunding website Kickstarter.com to raise awareness and collect pledges to promote her first book. "I released the book in January of this year, a sci-fi/fantasy novel titled Beyond This Life. It's the first book in the Through the Eyes of A Stranger series. It's been an amazing journey so far, but marketing electronic copies on the internet lacks that magical feeling I've always associated with books. So I thought it was time to take it on the road," says Kaye. How does she intend to promote ...

Mountain Park Civic Club will serve as this year's host for the 2nd annual Swing-A-Thon to be held on June 8, Saturday, from 12pm to 12am, for the purpose of raising $75,000 in order to purchase a brand new playground to replace the one that they had since 1985 which has been treated with chromate copper arsenic. Aside from the highlight activity which is swinging on Mountain Park's swing sets, Swing-A-Thon is an exclusive family-friendly event that also features craft and food vendors, kids' games, and other exciting activities that will surely be enjoyed by adults and ...

Joe "Joey" Lamielle has joined RE/MAX Alliance Group as a Realtor in the Sarasota office. A professional golfer for seven years, Lamielle has joined the Lee Brewer Team as a specialist in golf course properties and communities. A Sarasota resident for 24 years, Lamielle has a wealth of local knowledge and is currently working on obtaining his Graduate, REALTOR Institute (GRI) designation. He earned a bachelor's degree in Business Management from Florida Gulf Coast University in Fort Myers. He is a member of Suncoast Community Church and enjoys golfing, fishing, ...

Veronica Mars raised $2 million from fans in 11 hours and raised more than $5.7 million when the campaign ended on April 12, 2013. Rob Thomas put the campaign on KickStarter after failing to get interest from traditional investors. Veronica Mars may set crowdfunding records, but more than 1000 campaigns have raised over $100,000 on KickStarter and Indiegogo, with over 200 raising over $1million. While both KickStarter and Indiegogo provide a funding platform for people in the arts to promote their projects, technology companies have learned that they can bring their ...

Designed with simplicity in mind, ezPaycheck payroll software is the simple, flexible and affordable payroll tax solution for small businesses and accountants. To shorten the learning curve for the first time PC payroll system customers, halfpricesoft.com developers updated ezPaycheck 2013 with several new features: - The new intuitive graphical interface and form level buttons are so user-friendly that first time customers without an accounting background can start doing payroll immediately after installation. There is no long learning curve like there usually is with ...

'Auld Reekie' - is the Victorian nick name for the city of Edinburgh. It translates as 'old smokey' or 'old smelly' and was used by locals and those who travelled to Edinburgh to describe the city. Ghost hunt in Edinburgh on a ghost hunting event with Simply Ghost Nights, we begin the night with a one and a half hour terror tour of the Niddry Street Vaults, after the terror tour we begin the paranormal investigation of The Niddry Street Vaults. Back in the industrial revolution Edinburgh was clogged with smoke and fumes from the steam engines rolling in and out of ...

Spotlight Digital Magazine, is a unique, one-of-a-kind interactive new-media periodical- a 90 min. digital-content-magazine- that you watch. Each issue features exclusive, music, entertainment and urban lifestyle content delivered on DVD, novelty- "SKATEBOARD" or "RACE CAR" flash-drive or Digital Download- includes printed or interactive-digital content-guide. This unique package is the first of its kind to receive national magazine circulation through Rider Circulation Services Network- (RCS,) along with blanket California coverage through Newsways ...

The 32nd Annual Vintage Virginia Wine and Food Festival will run June 1st and 2nd at the Bull Run Special Events Center in Centreville, Virginia, and this year, festival-goers will notice a few changes to the typical vendor list. In the past, dozens of Virginia wineries have had a presence at the festival, and in 2013 that will be no different. Nearly 40 wineries are registered for the event, including Barboursville, Prince Michel, Trump and Veritas. What will differ at this year's Vintage Virginia is the 15+ gourmet food trucks scheduled to be onsite, as well as a special ...

Doxee, a pioneer of Cloud solutions for Customer Communication Management services, announced today its participation in the 2013 Xplor User Conference and Vendor Forum to be held at the TradeWinds Island Grand Hotel & Conference Center. Doxee Enterprise Communication Platform enables the design, development and delivery of mission-critical customer communication applications for businesses in telecom, banking, utilities, insurance and other sectors. At the Xplor Vendor Forum, Doxee, at booth #23, will showcase two applications developed on its cloud-based CCM ...

Creation, innovation and celebration are the cornerstones of Los Angeles-based My Favorite Company and its Treat Street brand (www.TreatStreet.com). The specialty candy company excels in presenting its confections in unique and unforgettable ways. What started out as light-hearted and amusing toy candy dispensers, Candy Poopers, have taken on a life of their own and will be on display at the 2013 Sweets & Snacks Expo, May 21-23 in Chicago. The Treat Street branded line of collectible Zoo, Sport, Pet, Holiday and Political Poopers are expanding to include Pirate, ...

Deed Poll Name Change is a new online service which allows anyone to change their name by either Deed Poll or Statutory Declaration quickly and cheaply online. Once the document has been downloaded, printed and authorised, the user has an official change of name document recognised by all UK government and non government agencies and companies. The Deed Poll Name Change system is online only and allows anyone in the UK who needs to officially change their name, and have an authorised document to confirm this, to simply fill in their details in to a simple website form ...

Today the Chairman of Michigan-based PryMarke, LLC signed a book contract with IGI Global of Pennsylvania to develop a book for those interested in economic and technological issues in Latin America. Bryan Christiansen said this is PryMarke's fifth contract with IGI Global to develop reference books on global business- and technology-related issues. He decided to develop the book after reviewing the experiences he acquired while doing his PhD field research in Costa Rica, Nicaragua, and Panama during 2004-06 in the Spanish language. "As Latin America becomes increasingly ...

In the past, most dermatologists have elected to cut out facial moles, which resulted in minor scarring. Today, more and more dermatologists are electing to refer their patients to Rejuv Skin & Laser Clinic in Eagan in support of the more favorable new scar-free technology. Dr. Selchow and his staff are experts at removing unwanted moles and lesions without freezing, surgery, or scarring. Dr. Selchow and his team can carefully and precisely remove unwanted imperfections with a CO2 laser without any downtime, or risk of scarring! The CO2 laser is a highly effective ...