An international team of scientists, led by researchers at the University of California, San Diego, has identified misfolding and other molecular anomalies in a key brain protein associated with autism spectrum disorders. Palmer Taylor, associate vice chancellor for Health Sciences at UC San Diego and dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences, and colleagues report in the September 10 issue of the Journal of Biological Chemistry that misfolding of a protein called neuroligin-3, due to gene mutations, results in trafficking deficiencies that may ...

In people with Alzheimer's, the brain becomes riddled with clumps of protein, forming what are known as amyloid plaques. Now, a report appearing in the September 17th print issue of Cell appears to have found a function for the amyloid precursor protein (APP for short) that yields the prime ingredient in those plaques. It turns out that APP is an iron oxidase whose job it is to convert iron from an unsafe form to a safe one for transport or storage. When APP fails to function properly, as it does in Alzheimer's disease, iron levels inside neurons mount to toxic levels. "This ...

For Immediate Release – September 10, 2010 – (Toronto) – Mental illness is associated with more lost work days than any other chronic condition, costing the Canadian economy $51 billion annually in lost productivity. In the first study of its kind, researchers from the Centre for Addiction and Mental Health (CAMH) have calculated the actual cost of mental health leave and found that on average it's double the cost of a leave for a physical illness. The study, published in the Journal of Occupational & Environmental Medicine, looked at data tracking the short-term disability ...

A study by U.S. Department of Agriculture (USDA) scientists and cooperators provides new details about how fertilizing soils with biosolids also introduces triclosan—an antibacterial agent in soaps and other cleaning supplies—into the environment. Farmers add "Class B" biosolids, also known as treated wastewater solids, to their fields as a fertilizer. These biosolids meet federal regulations for human health and safety, but little information has been obtained about their triclosan levels. Triclosan has not been identified as a human health hazard, but the U.S. Food ...

ALBUQUERQUE, NM — Two amateur astronomers who independently observed and videotaped an asteroid striking the giant planet Jupiter on June 3 have opened the possibility, in effect, of a giant research lab in space for planetary scientists. According to a paper by professional astronomers, expected to be published today online by Astrophysical Journal Letters, the asteroid was eight to 13 meters in diameter and packed a punch equivalent to a 250- to 1,000-kiloton nuclear bomb — smaller than the violent airburst that decimated trees for 40 kilometers around Tunguska in central ...

Pro Energy Consultants showed its continued commitment to being America's top brand in the building performance industry by hiring Tony Valentino as vice president of business development. Valentino has more than 25 years of experience in all areas of the HVAC business and will focus on building the Pro Energy brand. To promote the Pro Energy label, Valentino will be tasked with developing regional and national strategic business alliances, as well as increasing awareness of the company as a first-choice partner in the home performance industry. His experience has taught ...

Marci Hansen has been named vice president of marketing at Palo Alto Software. She brings more than 15 years of marketing experience with her. In her new role, she will oversee online and traditional marketing and promotion, business development and strategic partnerships for the company's full line of small business products. In addition, her team will be actively involved in new product development and introduction. "Marci arrives with a depth and breadth of experience that is almost unrivaled," said Palo Alto Software CEO Sabrina Parsons. "Having overseen everything ...

Small to Medium business owners are frequently trapped in the overwhelming amount of work and daily activities that are required simply for their business to maintain the status-quo. This prevents them from focusing on researching and implementing activities that will provide the business with the competitive edge to compete in the current economic climate and ultimately to expand and grow their business. Virtual Assistants (VA's) offer a simple solution to this problem by tailoring solutions to suit the individual needs of each business. Often, the idea of hiring another ...

Christine Heathman, LMT, ME, "Legend" in American Aesthetics, Industry Innovator, and CEO and Founder of GlyMed Plus , today announced the airing of her interview on Lifetime TV's "The Balancing Act" where she discusses the science of skin age management for Lifetime viewers who are tired of the barrage of advertiser claims, and want real solutions. According to host Christine Heathman, after 20 years of educating skin care professionals in the aesthetics field, she has noticed that more consumers are now interested in the science of effective skin care. Christine has ...

Kerley Signs is pleased to contribute to a famous Maryland landmark, the Ledo Restaurant. Tommy Marcos Sr. opened the restaurant on University Boulevard in Adelphi, MD back in 1955, and in the more than half-century since, the restaurant has continued to be a Marcos family business, first under Tommy Sr., then under his son Tommy Jr. and grandson Jimmy. The Ledo has become a favorite dining spot for Marylanders and many out-of state customers, thanks to its long history and distinctive square pizzas and other specialties. Kerley Signs, located in Landover, has been providing ...

Navigation Capital Partners (NCP), an Atlanta-based middle market private equity firm, announced the addition of Marissa Swesey as a senior analyst. Marissa will focus on managing the firm's communications with investors and key external relationships. "We are extremely pleased to have Marissa join our team," said Larry Mock, managing partner of Navigation Capital Partners. "Her experience and support will be a valued resource as we continue to actively seek investment opportunities in rapidly-growing, attractive markets." Prior to joining NCP, Marissa was an analyst ...

Glenn E. Davis, a highly experienced attorney whose practice focuses on antitrust issues, securities and corporate litigation, corporate compliance and white-collar criminal defense, has been selected Chair of the Litigation Department at the law firm Gallop, Johnson & Neuman, L.C. In announcing the move, Thomas J. Campbell, Managing Partner at Gallop, Johnson & Neuman, said, "Glenn Davis is highly respected in the legal profession in St. Louis and nationally for his expertise as a litigator and knowledge of antitrust, securities and business litigation issues. He has ...

Nantucket island is frequented by executives, CEO's, bankers, surgeons, bankers, Hollywood actors, sports stars, and average folks looking for a getaway. A short ferry trip to the island offers 5-star service at your fingertips. Fine seafood, spectacular sunsets, and exclusive golf clubs are some of the serene luxuries that lure people to Nantucket. Being such a desirable location, brides and grooms from as close as New York to as far as England select this lovely island for their destination weddings. If you are familiar with the island you might already know some of the ...

FortrezZ, LLC. Announces a new product: the Siren / Strobe Alarm Module. It will be on display for the first time at the CEDIA 2010 show in Atlanta, GA. The SSA01 Siren / Strobe Alarm is ready to be sold to distributors and installers of home automation, control, home security and monitoring systems. The module will fill a gap in the product market for wireless Siren / Strobe alarms and will be an integral part of the FortrezZ "Water and Freeze" detection, alarm, and damage prevention system. SSA01 is a Z-WaveTM enabled device and is fully compatible with any Z-WaveTM enabled ...

World class magic was on display and jaws were dropping as international card magician Jon Armstrong had traveled from Los Angeles California to appear at Adelaide's local magic club. On the first of September Jon gave his only Adelaide presentation at the historic Bomb Shelter on the corner of Ashley Road and South Road at Thebarton. For well beyond the 2 hours he was scheduled, Jon amazed novices and experts alike by turning the audience into magicians. One volunteer picked out the card another volunteer had secretly chosen. Another audience member shuffled a stack ...

The De Anza Chapter of the National Society of the Daughter of the American Revolution, NSDAR, announces the launch of its prestigious, nationally recognized American History Essay Contest for the 2010-2011 academic year. All 5-8-grade students are invited to celebrate America's history by completing essays on a historically significant topic relating to an American milestone. The contest is being co-chaired by Debbie Giese and Joanne Dudek from the De Anza NSDAR. Since 1957, schools across the nation have participated in this annual event and the essay topic this year ...

Local crafter, Brandy Cox has created a girls weekend away designed for crafters who love to rubber stamp. Brandy's Fall Stamping Getaway will offer two days and one of night of serious stamping, November 6th and 7th. This event is open to all levels of crafters and will include four technique classes with one-on-one hands-on instruction. Cox, who holds her own classes and stamping events out of her own studio in Huntersville, will instruct the classes. "First and foremost, this will be just a fun 'getaway' weekend for the ladies," said Cox. "But it's also a great ...

In conjunction with the launch of a range of handmade Pedicure Bowls and Accessories, Australia's Professional Spa Treatment supplier, Victoria's Essentials has announced the release of their range of premium, hand-cut Bowl Warming Stones. These stones have been designed to maintain water temperature during a pedicure as well as warm feet using the natural heating properties of stone. "Our aim was function and beauty," says Victoria Slater, founder of Victoria's Essentials. "We were attracted to the natural beauty of Australian Granite as it highlights the elegance ...

Sonny Valens an upcoming inspiring actor who is most remembered in Paramount Pictures "Freedom Writers" where he auditioned and beat out thousands of Hispanic actors to score the main role in one of two-time Oscar winner Hilary Swank's feature film "Freedom Writers". Working alongside industry notables such as Grey's Anatomy's Patrick Dempsey, recording artist Mario, and Imelda Staunton afforded Valens to learn a great deal on the set while working alongside these amazing talented actors, reinforcing his desires to become a successful working actor. Born in Upland California, ...

Television Frenzies is giving back. We are conducting a Silly Bandz Trading Day Fundraiser on October 2, 2010 from 10:00am until 1:00pm. This event will take place at Mayfair Mall, and proceeds with be donated to the Children's Hospital of Wisconsin. You may be asking yourself, why is TV Frenzies doing this. We say, why not? Purposeful and meaningful events like this that will lead to substantial donations for a Children's Hospital truly make me tremble inside. It makes me think of the all-powerful lyrics from the world famous song, The Greatest Love of All. Here at ...

Dreams become reality as KJ Garett publishes his novel, psychological horror, "Black Mass." For more than four decades, KJ Garett has written horror and mystery short stories under different pen names, he wrote for horror magazines, horror story websites, and paranormal websites. Writing is difficult for most people, yet even more so, for someone with a handicap, KJ's handicap is not visible; his handicap called dyslexia, making it hard to read and write. Others would tease him, and call him stupid yet his IQ is 185. He began writing to cure his "problem" while he was in ...

A high percentage of women in the premenopause and postmenopause years experience hot flashes and night sweats. In fact, the National Institutes of Health recently published a report called the "State-of-the-Science Statement on the Management of Menopause-Related Symptoms" (1). In this article, the authors write that 30% to 80% of women in menopause regularly experience this sudden, intense, hot, perspiring feeling in their face and upper body. A diminished level of estrogen has a direct effect on the hypothalamus, the part of the brain responsible for controlling our ...

Rodney Mesriani, Esq., founder and CEO of the Mesriani Law Group - one of the leading law firms in Los Angeles and Southern California - has attended this year's 29th Annual Convention of the Consumer Attorneys of Los Angeles (CAALA) held from September 2 to 5at the Palazzo Venetian Resort in Las Vegas, Nevada. As a long-time CAALA member, Rodney Mesriani regularly attends the organization's convention as part of his firm's effort to enhance their services to clients and to keep updates on the latest trend in their profession. The two-and a half day prestigious event, ...

Chicago, Illinois will play host to the 2010 Miss Leadership Pageant. The Miss Leadership Pageant is a traditional beauty pageant competition which is open to young ladies between the ages of 5 and 19. This Pageant is being promoted and organized by Waverly Media Group and headed by T.L. Inspirations. The Miss Leadership Pageant will be telecasted LIVE across the world and hosted at the Holiday Inn Chicago Midway in Chicago, IL. The pageant will be Friday, Saturday & Sunday, November 12-14, 2010. The mission of the Miss Leadership Pageant is to develop leadership skills ...

The CIO Healthcare Summit team invites CIOs and Senior IT Executives from national healthcare organizations to participate in the upcoming technology event as a speaker or panelist. Qualified presenters will receive complimentary airfare, accommodations, food and drink for the duration of the event, as well as full access to all agenda sessions and networking opportunities. If you are interested in participating in the event's agenda, please visit http://www.ciohealthcaresummit.com/callforspeakers/. To be held December 12-15, 2010 in Scottsdale, Arizona, the CIO Healthcare ...