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Small but mighty: the hidden power of broccoli sprouts

Small but mighty: the hidden power of broccoli sprouts
2023-10-24
Remember when your parents used to say, “Eat your greens, they are good for you”? Well, they were really onto something. Several studies have shown that higher intakes of cruciferous vegetables like broccoli, one of the most widely consumed vegetables in the United States, are associated with reduced risks of diseases such as diabetes and cancer, thanks to their organosulfur compounds, such as glucosinolates and isothiocyanates that exhibit a broad spectrum of bioactivities including antioxidant activity. However, few studies have focused on ...

Are retrospective adjustments to sustainability reports helping CEOs score a bonus?

Are retrospective adjustments to sustainability reports helping CEOs score a bonus?
2023-10-24
A lack of clarity around sustainability reporting is allowing ASX-listed companies to retrospectively alter figures, ensuring CEO bonus pay tied to these metrics is realised, new research suggests.  Sustainability reports serve as critical tools for investors, regulators and other stakeholders to gauge a company's environmental, social, and governance (ESG) performance. They highlight issues such as environmental pollution and worker safety that might otherwise be overlooked. Close to 90% of ASX top 200 companies provide detailed ESG information. Many of these ...

Cathode active materials for lithium-ion batteries could be produced at low temperatures

Cathode active materials for lithium-ion batteries could be produced at low temperatures
2023-10-24
Layered lithium cobalt oxide, a key component of lithium-ion batteries, has been synthesized at temperatures as low as 300°C and durations as short as 30 minutes. Lithium ion batteries (LIB) are the most commonly used type of battery in consumer electronics and electric vehicles. Lithium cobalt oxide (LiCoO2) is the compound used for the cathode in LIB for handheld electronics. Traditionally, the synthesis of this compound requires temperatures over 800°C and takes 10 to 20 hours to complete. A team of researchers at Hokkaido University and Kobe University, led by Professor Masaki Matsui at Hokkaido University’s Faculty of Science, have developed a new method to ...

How to slow the spread of deadly ‘superbugs’

How to slow the spread of deadly ‘superbugs’
2023-10-24
Harnessing new advances in genomic surveillance technology could help detect the rise of deadly ‘superbugs’ and slow their evolution and spread, improving global health outcomes, a new Australian study suggests. Antimicrobial resistance occurs when bacteria, viruses, fungi and parasites change over time and no longer respond to the medicines and chemicals we use to kill them. These ‘superbugs’ make infections harder to treat and increase the risk of disease spread, severe illness and death. Without significant intervention, global annual deaths involving antimicrobial resistance are estimated ...

Burning sugarcane possible cause of mystery kidney disease in agricultural workers

2023-10-24
AURORA, Colorado (October 23, 2023) - The burning of sugarcane and rice husks may be releasing a toxicant causing a mysterious kidney disease in agricultural workers, according to a paper out today in the American Journal of Kidney Diseases. An ongoing epidemic of chronic kidney disease has been observed among manual laborers in hot agricultural communities throughout the world, including along the Pacific coast of Central America, India and Sri Lanka. While heat stress and climate change have contributed to this epidemic, researchers have identified tiny silica particles released from sugarcane ash that can be inhaled or ingested through contaminated drinking water that cause ...

Researchers identify ‘switch’ to activate cancer cell death

Researchers identify ‘switch’ to activate cancer cell death
2023-10-24
A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die. This new ability to trigger programmed cell death could open the door for improved cancer treatments. The findings were published Oct. 14 in the Nature journal Cell Death & Differentiation. CD95 receptors, also known as Fas, are called death receptors. These protein receptors reside on cell membranes. When activated, ...

Role of innate immunity in SARS-CoV-2 infection

2023-10-24
https://doi.org/10.1016/j.bsheal.2023.08.005   During severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, activated macrophages, dendritic cells, neutrophils, and natural killer cells are the first defense against infection. These immune effectors trap and ingest the virus, kill infected epithelial cells, or produce anti-viral cytokines. Evidence suggests that aging, obesity, and mental illness can lead to weakened innate immunity and, thus, are all associated with elevated infection and severe disease progression of coronavirus disease 2019 (COVID-19). ...

Viral rebound and safety of nirmatrelvir/ritonavir for lung-transplant recipients infected with SARS-CoV-2

2023-10-24
https://doi.org/10.1016/j.bsheal.2023.08.004   Data on the viral rebound and safety of nirmatrelvir/ritonavir in lung transplant (LTx) recipients are limited. The study prospectively followed four LTx recipients. Clinical characteristics, viral RNA dynamic in throat swabs, and tacrolimus blood concentration were monitored regularly. All four LTx recipients, aged 35–74 years, were not vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). They got coronavirus disease 2019 (COVID-19) after ...

Residents unprepared for wildland fires, face barriers in implementing prevention measures: York U study

2023-10-23
TORONTO, October 23, 2023 –This year, Canada saw the worst wildfire season in its history, with fires destroying homes, displacing thousands of residents, and burning the largest area since contemporary records began in 1983. Much of this damage to communities could be reduced with better wildfire preparedness – but wildland urban interface (WUI) communities often face significant barriers in implementing these improvements, according to a study by York University’s Disaster and Emergency Management researchers. According to the study, Determinants of residential wildfire mitigation uptake: A ...

Diffraction-limited visible imaging for large aperture telescopes: development and application of piezoelectric deformable secondary mirror

Diffraction-limited visible imaging for large aperture telescopes: development and application of piezoelectric deformable secondary mirror
2023-10-23
A new publication from Opto-Electronic Advances, 10.29026/oea.2023.230039 discusses diffraction-limited visible imaging for large aperture telescopes.   The deformable mirror used in adaptive optics can change its surface to instantly correct the static wavefront aberration of the optical system and atmospheric turbulence wavefront disturbance. This allows the optical system to automatically adapt to changes in the environment and maintain optimal performance. High-resolution astronomical observation, laser atmospheric transmission, and biomedical imaging all make extensive use ...

Texas A&M joins multimillion-dollar moon orbit tracking project

2023-10-23
Texas A&M University is joining a multi-university team on a major research project to track objects orbiting the moon. The Air Force Research Laboratory is awarding up to $5 million over five years for the Space University Research Initiative (SURI). “The SURI is an outstanding initiative to train our next-generation workforce. We look forward to carrying out creative research aimed at addressing astronautical challenges in cislunar space,” said Dr. Manoranjan Majji, an associate professor and Josey Family Foundation Faculty Fellow in the Department of Aerospace Engineering at ...

Nurse practitioners and physicians are similarly likely to inappropriately prescribe medications to older patients

2023-10-23
Embargoed for release until 5:00 p.m. ET on Monday 23 October 2023 Annals of Internal Medicine Tip Sheet @Annalsofim Below please find summaries of new articles that will be published in the next issue of Annals of Internal Medicine. The summaries are not intended to substitute for the full articles as a source of information. This information is under strict embargo and by taking it into possession, media representatives are committing to the terms of the embargo not only on their own behalf, but also on behalf of the organization ...

UArizona researchers probe how a piece of the moon became a near-Earth asteroid

UArizona researchers probe how a piece of the moon became a near-Earth asteroid
2023-10-23
In 2021, a team of University of Arizona astronomers suggested that a recently discovered near-Earth asteroid, Kamo`oalewa, could be a chunk of the moon. Two years after the striking discovery, another UArizona research group has found that a rare pathway could have enabled this to happen. So far, only distant asteroids from beyond the orbit of Mars have been considered a source of near-Earth asteroids, said Renu Malhotra, Regents Professor of Planetary Sciences and a senior author on the paper. "We are now establishing that the moon is a more likely source ...

Rare lungs cells reveal another surprise with implications for cystic fibrosis

Rare lungs cells reveal another surprise with implications for cystic fibrosis
2023-10-23
A new study by University of Iowa researchers finds that rare lung cells known as pulmonary ionocytes facilitate the absorption of water and salt from the airway surface. This function is exactly the opposite of what was expected of these cells and may have implications for cystic fibrosis (CF) lung disease.   Five years ago, scientists reported the unexpected discovery that ionocytes—a cell type commonly found in fish gills and frog skin—are also present in the lining of human lungs and airways. These pulmonary ionocytes were particularly interesting to CF researchers because although they only account for about 1% of all the cells in the airway ...

New UCF project is harnessing virtual reality to teach quantum computing

2023-10-23
ORLANDO, Oct. 23, 2023 – Researchers from the University of Central Florida, University of Texas at Dallas and Vanderbilt University have received a three-year, $927,203 grant for advancing future quantum education by using virtual reality (VR) and machine learning to identify and address misconceptions regarding quantum information science (QIS). The U.S. National Science Foundation-funded project started in August 2023 and leverages QubitVR, a quantum-education VR application previously developed ...

Major pathologic response to neoadjuvant pembrolizumab in advanced melanoma trial exceeds 50 percent

2023-10-23
In exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major pathologic response in more than half of surgical specimens taken from patients who had been treated with neoadjuvant (pre-operative) pembrolizumab. These and other results of the analyses are presented as a proffered paper (Abstract LBA48) at the European Society of Medical Oncology (ESMO) Congress 2023 in Madrid, Spain, on Monday, October 23, by Sapna P. Patel, MD, chair of the SWOG melanoma committee and associate professor of melanoma medical oncology at the University of Texas MD Anderson Cancer Center. Patel is principal investigator ...

NYSCF announces 2023 Class of NYSCF – Robertson Investigators

2023-10-23
The New York Stem Cell Foundation (NYSCF) today announced the 2023 class of NYSCF – Robertson Investigators, welcoming three outstanding stem cell researchers into the NYSCF Innovator community. The NYSCF – Robertson Stem Cell Investigator Awards support promising early career scientists whose cutting-edge research holds the potential to accelerate treatments and cures through the NYSCF – Robertson Stem Cell Investigator Awards. The awards provide unrestricted seed funding – $1.5 million over five years –  for scientists who have established their own, ...

Researchers capture first images of a radio 'ring of fire' solar eclipse

Researchers capture first images of a radio ring of fire solar eclipse
2023-10-23
Researchers at New Jersey Institute of Technology’s Center for Solar-Terrestrial Research (NJIT-CSTR) have captured the Oct. 14 solar eclipse in a way never seen before — recording the first radio images of an annular eclipse’s famous “ring of fire” effect. The eclipse was partially visible to much of the continental U.S. for several hours that Saturday, though the full “ring of fire” effect was only visible for less than five minutes, and only for those within its 125-mile-wide path of annularity. However, the new observations of the radio Sun’s eclipse — ...

University of Montana leads $12.3 million contract to advance TB vaccine

University of Montana leads $12.3 million contract to advance TB vaccine
2023-10-23
MISSOULA – The National Institutes of Health recently awarded a $12.3 million contract to the University of Montana to develop a novel vaccine adjuvant for use in a tuberculosis vaccine. Adjuvants are substances that boost the effectiveness of vaccines. The five-year award went to UM’s Center for Translational Medicine and its partners. The contract is titled “Development of UM-1098: A Novel Synthetic Th17 Inducing Adjuvant and Delivery System.” “The development and clinical evaluation of safe and effective ...

People who communicate more, show expertise are more likely to be seen as essential team members

2023-10-23
A new study sheds light on the vital role of communication and expertise within organizations, revealing their impact on group performance. Researchers examined how individuals become part of communication networks and the effect of selection processes on group performance. The study found that people who communicated more during training were more likely to be chosen as a central member of the network. In addition, teams that chose their central member performed as well as and often better than teams whose central member was randomly assigned. The study, by researchers ...

Apoptotic cells may drive cell death in hair follicles during regression cycle

Apoptotic cells may drive cell death in hair follicles during regression cycle
2023-10-23
“Revealing the stem cell niche self-renewal dynamics is important not only for understanding tissue homeostasis but also for understanding the initiation of cancer [7].” BUFFALO, NY- October 23, 2023 – A new research paper was published in Oncotarget's Volume 14 on October 19, 2023, entitled, “Apoptotic cells may drive cell death in hair follicles during their regression cycle.” Intravital microscopy in live mice has shown that the elimination of epithelial cells during hair follicle regression involves supra-basal cell differentiation and basal cell apoptosis through synergistic action of TGF-β (transforming ...

$3.6 million NIH award funds research to treat painful diabetic neuropathy

$3.6 million NIH award funds research to treat painful diabetic neuropathy
2023-10-23
COLUMBUS, Ohio – A $3.6 million award from the National Institutes of Health will allow neurosurgical, neurology and neuroscience researchers at The Ohio State University Wexner Medical Center and College of Medicine to test a novel diagnosis and treatment combination for painful diabetic neuropathy. The approach combines spinal cord stimulation with measurement of small fiber nerve activity using a patent-pending device called Detecting Early Neuropathy (DEN). Diabetes is a growing health concern worldwide, ...

Superdeep diamonds provide a window on supercontinent growth

Superdeep diamonds provide a window on supercontinent growth
2023-10-23
Washington, DC—Diamonds contain evidence of the mantle rocks that helped buoy and grow the ancient supercontinent Gondwana from below, according to new research from a team of scientists led by Suzette Timmerman—formerly of the University of Alberta and now at the University of Bern—and including Carnegie’s Steven Shirey, Michael Walter, and Andrew Steele. Their findings, published in Nature, demonstrate that superdeep diamonds can provide a window through space and time into the supercontinent growth and formation ...

American Cancer Society awards pilot funding to University of Cincinnati Cancer Center for early-stage investigators

American Cancer Society awards pilot funding to University of Cincinnati Cancer Center for early-stage investigators
2023-10-23
The American Cancer Society has awarded the University of Cincinnati Cancer Center an Institutional Research Grant. Cancer Center member David Plas, PhD, is primary investigator for the grant, with members Maria Czyzyk-Krzeska, MD, PhD, and Kathryn Wikenheiser-Brokamp, MD, PhD, serving as co-principal investigators. The American Cancer Society awards Institutional Research Grants to academic and nonprofit organizations that have a track record of outstanding cancer research and a pool of experienced researchers who can mentor junior faculty. The purpose is to support early-stage ...

Climate is increasing risk of high toxin concentrations in Northern US lakes

Climate is increasing risk of high toxin concentrations in Northern US lakes
2023-10-23
Washington, DC— As climate change warms the Earth, higher-latitude regions will be at greater risk for toxins produced by algal blooms, according to new research led by Carnegie’s Anna Michalak, Julian Merder, and Gang Zhao. Their findings, published in Nature Water, identify water temperatures of 20 to 25 degrees Celsius (68 to 77 degrees Fahrenheit) as being at the greatest risk for developing dangerous levels of a common algae-produced toxin called microcystin.   Harmful algal blooms result when bodies of water get overloaded with nitrogen and phosphorus ...
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