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Humans were apex predators for two million years

Humans were apex predators for two million years
2021-04-05
Researchers at Tel Aviv University were able to reconstruct the nutrition of stone age humans. In a paper published in the Yearbook of the American Physical Anthropology Association, Dr. Miki Ben-Dor and Prof. Ran Barkai of the Jacob M. Alkov Department of Archaeology at Tel Aviv University, together with Raphael Sirtoli of Portugal, show that humans were an apex predator for about two million years. Only the extinction of larger animals (megafauna) in various parts of the world, and the decline of animal food sources toward the end of the stone age, led humans to gradually increase the vegetable element in their nutrition, until finally they had no choice but to domesticate both plants and animals - and became farmers. "So far, attempts to reconstruct the diet of stone-age humans ...

What are forever chemicals, and do they last forever? (video)

What are forever chemicals, and do they last forever? (video)
2021-04-05
WASHINGTON, April 5, 2021 -- Forever chemicals are known for being water-, heat- and oil-resistant, which makes them useful in everything from rain jackets to firefighting foams. But the chemistry that makes them so useful also makes them stick around in the environment and in us -- and that could be a bad thing: https://youtu.be/tqKEG5LxPiY. INFORMATION: Reactions is a video series produced by the American Chemical Society and PBS Digital Studios. Subscribe to Reactions at http://bit.ly/ACSReactions and follow us on Twitter @ACSReactions. The American Chemical Society (ACS) is a nonprofit organization chartered by the U.S. Congress. ACS' mission is to advance the broader ...

Deep dive into key COVID-19 protein is a step toward new drugs, vaccines

Deep dive into key COVID-19 protein is a step toward new drugs, vaccines
2021-04-05
CORVALLIS, Ore. - Researchers in the Oregon State University College of Science have taken a key step toward new drugs and vaccines for combating COVID-19 with a deep dive into one protein's interactions with SARS-CoV-2 genetic material. The virus' nucleocapsid protein, or N protein, is a prime target for disease-fighting interventions because of the critical jobs it performs for the novel coronavirus' infection cycle and because it mutates at a comparatively slow pace. Drugs and vaccines built around the work of the N protein carry the potential to be highly effective and for longer periods of time - i.e., less susceptible to resistance. Among the SARS-CoV-2 proteins, ...

New 'quantum' approach helps solve an old problem in materials science

New 'quantum' approach helps solve an old problem in materials science
2021-04-05
Ishikawa, Japan - One of the most important classes of problems that all scientists and mathematicians aspire to solve, due to their relevance in both science and real life, are optimization problems. From esoteric computer science puzzles to the more realistic problems of vehicle routing, investment portfolio design, and digital marketing--at the heart of it all lies an optimization problem that needs to be solved. An appealing technique often used in solving such problems is the technique of "quantum annealing", a framework that tackles optimization problems by using "quantum tunneling"--a quantum physical phenomenon--to pick out an optimum solution out of several candidate solutions. ...

POLST and other advance medical planning should not be a one-time conversation

POLST and other advance medical planning should not be a one-time conversation
2021-04-05
INDIANAPOLIS -- The high incidence of COVID-19 and resulting sudden changes in the health of many long-stay nursing home residents across the country have amplified the importance of advance care planning and the need for periodic review of the process, especially as widespread vaccination changes the calculus of the disease. Two new studies from Indiana University and Regenstrief Institute focus on POLST, a medical order form widely used in nursing homes that documents what life-sustaining treatments a person prefers to receive or not receive, such as hospitalization or comfort-focused care. The studies, published online ...

Adult nocturnal fishflies found to visit flowers for food

Adult nocturnal fishflies found to visit flowers for food
2021-04-05
Researchers from Kumamoto University (Japan) have found that adult nocturnal fishflies (Neochauliodes amamioshimanus), which are typically aquatic insects, feed on pollen at night. They also present circumstantial evidence suggesting that this species not only forages in flowers, but is also a supplementary pollinator. Their work sheds light on the terrestrial life of adult fishflies, which has been a mystery until now. Megaloptera is a small taxon (about 400 species worldwide) consisting of the families Sialidae (alderflies) and Corydalidae (dobsonflies and fishflies), and is considered to be one of the oldest groups of insects that undergo complete metamorphosis. The biology of the fishfly's aquatic larvae, which were sometimes used as folk remedies in Japan, is relatively well understood. ...

Doping by athletes could become tougher to hide with new detection method

2021-04-05
WASHINGTON, April 5, 2021 -- As the world awaits the upcoming Olympic games, a new method for detecting doping compounds in urine samples could level the playing field for those trying to keep athletics clean. Today, scientists report an approach using ion mobility-mass spectrometry to help regulatory agencies detect existing dopants and future "designer" compounds. The researchers will present their results today at the spring meeting of the American Chemical Society (ACS). ACS Spring 2021 is being held online April 5-30. Live sessions will be hosted April 5-16, and on-demand and networking content will continue through April 30. The meeting features nearly 9,000 presentations ...

Making cleaner, greener plastics from waste fish parts

Making cleaner, greener plastics from waste fish parts
2021-04-05
WASHINGTON, April 5, 2021 -- Polyurethanes, a type of plastic, are nearly everywhere -- in shoes, clothes, refrigerators and construction materials. But these highly versatile materials can have a major downside. Derived from crude oil, toxic to synthesize, and slow to break down, conventional polyurethanes are not environmentally friendly. Today, researchers discuss devising what they say should be a safer, biodegradable alternative derived from fish waste -- heads, bones, skin and guts -- that would otherwise likely be discarded. The researchers will present their results today at the spring meeting of the American Chemical Society (ACS). ACS Spring 2021 is being held online April 5-30. Live sessions will be hosted ...

Paleopharmaceuticals from Baltic amber might fight drug-resistant infections

Paleopharmaceuticals from Baltic amber might fight drug-resistant infections
2021-04-05
WASHINGTON, April 5, 2021 -- For centuries, people in Baltic nations have used ancient amber for medicinal purposes. Even today, infants are given amber necklaces that they chew to relieve teething pain, and people put pulverized amber in elixirs and ointments for its purported anti-inflammatory and anti-infective properties. Now, scientists have pinpointed compounds that help explain Baltic amber's therapeutic effects and that could lead to new medicines to combat antibiotic-resistant infections. The researchers will present their results today at the spring meeting of the American Chemical Society (ACS). ACS Spring 2021 is being held online ...

Certain high blood pressure medications may alter heart risk in people with HIV

2021-04-05
DALLAS, April 5, 2021 -- When people with human immunodeficiency virus (HIV) develop high blood pressure, the type of medication chosen for their initial treatment may influence their risk of heart disease, stroke and heart failure, according to new research published today in Hypertension, an American Heart Association journal. With current anti-retroviral medications, people with HIV are able to live longer. However, people with HIV receiving anti-retroviral therapy (ART) are more likely to develop high blood pressure (hypertension) and hypertension-related heart problems than people who do not have the virus. The current study is the first to examine how the choice of blood pressure medications influences the long-term risk of heart disease, stroke and ...

Rise of oxygen on Earth: Initial estimates off by 100 million years

Rise of oxygen on Earth: Initial estimates off by 100 million years
2021-04-05
New research shows the permanent rise of oxygen in our atmosphere, which set the stage for life as we know it, happened 100 million years later than previously thought. A significant rise in oxygen occurred about 2.43 billion years ago, marking the start of the Great Oxidation Episode -- a pivotal moment in Earth's history.  An international research team including a UC Riverside scientist analyzed rocks from South Africa formed during this event. Findings, published this week in the journal Nature, include the discovery that oxygen fluctuated dramatically after its early appearance until it became a permanent constituent of the atmosphere much later. These ...

NIH scientists develop breath test for methylmalonic acidemia

2021-04-05
Researchers at the National Institutes of Health have developed a breath test that measures how well patients with methylmalonic acidemia (MMA) respond to receiving liver or combined liver and kidney transplantation. Researchers also used the test to assess the severity of the disease in people and help determine if they would benefit from surgical or experimental genomic therapies that target the liver. The study results were published in Genetics in Medicine. Scientists at the National Human Genome Research Institute (NHGRI) led the project team, with collaborators from the National ...

Long wait times increase for children seeking emergency care for mental health

2021-04-05
Rates of prolonged visits for pediatric mental health emergency department (ED) visits increased over a decade, in contrast to non-mental health visits for which visit times remained stable, according to a study published in the journal Pediatrics. From 2005-2015, rates of ED visits lasting over six hours for children presenting for mental health issues jumped from 16 percent to nearly 25 percent, while rates of visits lasting over 12 hours increased from 5 percent to nearly 13 percent. "The trend of increasingly long ED visits for pediatric mental health problems likely represents worsening access to essential mental health services. This is concerning, especially since during the COVID-19 pandemic we are seeing substantially more children coming ...

New paper shows benefits of Louisiana coastal restoration to soil carbon sequestration

2021-04-05
BATON ROUGE, La. (March 2021) - Without restoration efforts in coastal Louisiana, marshes in the state could lose half of their current ability to store carbon in the soil over a period of 50 years, according to a new paper published in American Geophysical Union Journal of Geophysical Research Biogeosciences. "This reduction in capacity could significantly alter the global carbon budget, given that Louisiana's marsh soils account for between 5 and 21 percent of the global soil carbon storage in tidally influenced wetlands," said Melissa Baustian, lead author and coastal ecologist at The Water Institute of the Gulf. The article, "Long-term carbon sinks in marsh soils of coastal Louisiana are at risk to wetland loss" ...

New study ties solar variability to the onset of decadal La Nina events

2021-04-05
A new study shows a correlation between the end of solar cycles and a switch from El Nino to La Nina conditions in the Pacific Ocean, suggesting that solar variability can drive seasonal weather variability on Earth. If the connection outlined in the journal Earth and Space Science holds up, it could significantly improve the predictability of the largest El Nino and La Nina events, which have a number of seasonal climate effects over land. For example, the southern United States tends to be warmer and drier during a La Nina, while the northern U.S. tends to be colder ...

Outside factors may help children develop internal control

2021-04-05
PULLMAN, Wash. - The ability to control your own behavior, known as executive function, might not exist all in your head. A new theory proposes that it develops with many influences from outside the mind. The theory, detailed in Perspectives on Psychological Science, draws on dynamic systems theory which originated in mathematics and physics and has been used to describe complex organizing phenomena like cloud formation and flying patterns of birds. Now, a research team led by Washington State University human development assistant professor Sammy Perone is applying ...

Less sugar, please! New studies show low glucose levels might assist muscle repair

Less sugar, please! New studies show low glucose levels might assist muscle repair
2021-04-03
Tokyo, Japan - Researchers from Tokyo Metropolitan University have shown that skeletal muscle satellite cells, key players in muscle repair, proliferate better in low glucose environments. This is contrary to conventional wisdom that says mammalian cells fare better when there is more sugar to fuel their activities. Because ultra-low glucose environments do not allow other cell types to proliferate, the team could produce pure cultures of satellite cells, potentially a significant boost for biomedical research. Healthy muscles are an important part of a healthy life. With the wear and tear of everyday use, our muscles continuously repair themselves to keep them in top condition. In recent years, scientists have begun to understand how muscle repair ...

Tracking receptor proteins can unveil molecular basis of memory and learning

Tracking receptor proteins can unveil molecular basis of memory and learning
2021-04-03
The neurons in our nervous system "talk" to each other by sending and receiving chemical messages called neurotransmitters. This communication is facilitated by cell membrane proteins called receptors, which pick up neurotransmitters and relay them across cells. In a recent study published in Nature Communications, scientists from Japan report their findings on the dynamics of receptors, which can enable understanding of the processes of memory formation and learning. The regulation of receptor movement and localization within the neuron is important for synaptic plasticity, an important process in the central nervous system. A specific type of ...

Deprivation is 'driving' Covid-19 ethnic disparities, claims new analysis

Deprivation is 'driving' Covid-19 ethnic disparities, claims new analysis
2021-04-03
DEPRIVATION among society at large is 'driving' Covid-19 disparities among minority ethnic groups - predominantly South Asian and Black African or Caribbean populations - and could be considered the main cause of disproportionate infection rates, hospitalisation and deaths experienced by these populations, according to new analysis from the University of Leicester. The study, supported by the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre (BRC) comes a day after a government-commissioned review concluded race and racism have become less important factors in explaining social disparities in the UK. Researchers at the University of Leicester used UK Biobank data of 407,830 South Asian, Black ...

Prioritizing who gets vaccinated for COVID-19 saves lives

2021-04-03
Waiting for your turn can be frustrating, especially when it comes to COVID-19 vaccinations. But prioritizing who receives the limited supply of vaccines available saves lives and reduces spread of infection, according to a study published today in the journal PNAS from the University of California, Davis. While there is mostly universal agreement that older people should be prioritized, debates are currently underway about prioritizing a variety of other groups. Still others argue against targeting at all. "Prioritization has benefits because people differ in at least two key ways -- their risk of infection and the likelihood of serious consequences from infection," said senior author ...

Michigan's Middle Eastern and North African population face barriers to optimal health

Michigan's Middle Eastern and North African population face barriers to optimal health
2021-04-02
Within southeast Michigan's Middle Eastern and North African community, those who worry about deportation or believe they've been treated unfairly are likely to face more adverse conditions associated with poor health, including food insecurity and financial distress. The MENA people who face several of these barriers are also more likely to report chronic illness and mental health issues as well as worse overall health. That's according to a new study by the University of Michigan Rogel Cancer Center, the University of Michigan School of Public Health, and the Arab Community Center for ...

OECD PISA report on student growth mindset to be released April 8

2021-04-02
Washington, April 2, 2021--The Organisation for Economic Co-operation and Development (OECD) will release a new PISA report on student growth mindset on Thursday, April 8 at 5:00 a.m. ET, followed by a press conference held in collaboration with the American Educational Research Association (AERA) and the Yidan Prize Foundation at 10:30 a.m. ET. The new report "Sky's the limit: Growth mindset, students, and schools in PISA" provides analyses on student growth mindset, a concept much discussed in the current field of psychology. Growth mindset is the belief that someone's ability and intelligence can be developed over time. PISA collected international ...

Research reveals why redheads may have different pain thresholds

2021-04-02
BOSTON - New research led by investigators at Massachusetts General Hospital (MGH) provides insights on why people with red hair exhibit altered sensitivity to certain kinds of pain. The findings are published in Science Advances. In people with red hair (as in numerous other species of animals with red fur), the pigment-producing cells of the skin--called melanocytes--contain a variant form of the melanocortin 1 receptor. This receptor sits on the cell surface, and if it becomes activated by circulating hormones called melanocortins, it causes the melanocyte to switch from generating yellow/red melanin pigment to producing brown/black melanin pigment. Earlier work by David E. Fisher, MD, PhD, director of the Mass General Cancer Center's ...

Study identifies possible COVID-19 drugs -- including several that are FDA-approved

2021-04-02
PHILADELPHIA - A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has identified nine potential new COVID-19 treatments, including three that are already approved by the Food and Drug Administration (FDA) for treating other diseases. The team, whose findings were published in Cell Reports, screened thousands of existing drugs and drug-like molecules for their ability to inhibit the replication of the COVID-19-causing coronavirus, SARS-CoV-2. In contrast to many prior studies, the screens tested the molecules for anti-coronaviral activity in a variety of cell types, including human airway-lining cells that are similar to the ones principally affected in COVID-19. Of ...

Study sheds light on interplay among PTSD, combat experience, alcohol use

Study sheds light on interplay among PTSD, combat experience, alcohol use
2021-04-02
A new Veterans Affairs study finds that combat experience is associated with a higher risk of alcohol use to cope with PTSD symptoms. But the connection is weaker when accounting for the severity of the PTSD. The findings appeared online in the Journal of Dual Diagnosis in March 2021. In an observational study of more than 11,000 men with at least one traumatic experience, the researchers found that those with combat experience were much more likely than those without to report drinking alcohol to cope with PTSD. The diversity of traumatic experiences, the severity of PTSD, and diagnoses ...
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