Have you forgotten where you laid your keys? Ever wondered where you had parked your car? Or having trouble remembering the name of the new neighbor? Unfortunately, these things seem to get worse as one gets older. A big question for researchers is where does benign forgetfulness end and true disease begin? One of the keys to having a healthy brain at any age is having a healthy blood-brain barrier, a complex interface of blood vessels that run through the brain. Researchers reviewed more than 150 articles to look at what happens to the blood-brain barrier as we age. Their findings were published March 15 in Nature ...

LOS ALAMOS, N.M., March 18, 2021--A new, simpler solution process for fabricating stable perovskite solar cells overcomes the key bottleneck to large-scale production and commercialization of this promising renewable-energy technology, which has remained tantalizingly out of reach for more than a decade. "Our work paves the way for low-cost, high-throughput commercial-scale production of large-scale solar modules in the near future," said Wanyi Nie, a research scientist fellow in the Center of Integrated Nanotechnologies at Los Alamos National Laboratory and corresponding ...

During a pandemic like COVID-19, vulnerable countries are traditionally the focus of global attention and concern. However, new research suggests that we need to rebuild our understanding. A study published in KeAi's Global Health Journal, examined the relationship between state vulnerabilities (measured using the Fragile States Index (FSI) from Fund for Peace) and COVID-19 incidence and death rates in 146 countries. The FSI consists of 12 specific indicators covering cohesion, economy, politics and society. "When using the total FSI score for statistical analysis, we were surprised to find that, overall, the more fragile countries had lower cumulative incidence and fatality rates for COVID-19," explains one of the study's authors, Yangmu ...

In new findings published online March 18, 2021 in the journal Cancer Cell, an international team of researchers, led by scientists at University of California San Diego School of Medicine and Moores Cancer Center, describe how pancreatic cancer cells use an alternative method to find necessary nutrients, defying current therapies, to help them grow and spread. Pancreatic cancer accounts for roughly 3 percent of all cancers in the United States, but it is among the most aggressive and deadly, resulting in 7 percent of all cancer deaths annually. Pancreatic cancer is especially deadly once it metastasizes, with the number of people who are alive five years later declining from 37 percent to just 3 percent. All cancer cells require a constant supply of nutrients. Some types ...

Smart glass can change its color quickly through electricity. A new material developed by chemists of Ludwig-Maximilians-Universität (LMU) in Munich has now set a speed record for such a change. On the highway at night. It rains, the bright headlights of the car behind you are blinding. How convenient to have an automatically dimming rearview mirror in such a case. Technically, this helpful extra is based on electrochromic materials. When a voltage is applied, their light absorption and color change. Controlled by a light sensor, the rearview mirror can thus filter out strongly dazzling light. Recently, experts discovered that, in addition to established inorganic electrochromic materials, a new generation of highly ordered lattice structures can also be equipped ...

KINSHASA, DEMOCRATIC REPUBLIC OF CONGO (March 18, 2021) - A new study in the journal Conservation Science and Practice finds that restaurants in urban areas in Central Africa play a key role in whether protected wildlife winds up on the menu. The study, by a team of scientists from Michigan State University, Wildlife Conservation Society (WCS), and University of Maryland, used a crime science "hot product" approach, which looks at frequently stolen items coveted by thieves. The approach offered new insights into wildlife targeted by the urban wild meat trade and can inform urban wildlife policies. The study engaged lower, middle, and upper-level tiered restaurants to understand which species were traded. ...

Detailed, new analysis published this week in the British Medical Journal (BMJ) Open highlights significant concerns about a growing issue of sex selective abortion of girls in Nepal. Drawing on census data from 2011 and follow-on survey data from 2016, the social scientists estimate that roughly one in 50 girl births were 'missing' from records (i.e. had been aborted) between 2006-11 (22,540 girl births in total). In the year before the census (June 2010 - June 2011) this had risen to one in 38. For certain areas of the country, the practice was more widespread. In Arghakhanchi, the most affected district, one in every six girl births were 'missing' in census data. In the Kathmandu Valley, Nepal's main urban centre, around 115 boys are born for ...

Anyone who has watched an infant's eyes follow a dangling trinket dancing in front of them knows that babies are capable of paying attention with laser focus. But with large areas of their young brains still underdeveloped, how do they manage to do so? Using an approach pioneered at Yale that uses fMRI (or functional magnetic resonance imaging) to scan the brains of awake babies, a team of university psychologists show that when focusing their attention infants under a year of age recruit areas of their frontal cortex, a section of the brain involved in more advanced functions that was previously thought to be immature in babies. The findings were ...

At the heart of clouds are ice crystals. And at the heart of ice crystals, often, are aerosol particles - dust in the atmosphere onto which ice can form more easily than in the open air. It's a bit mysterious how this happens, though, because ice crystals are orderly structures of molecules, while aerosols are often disorganized chunks. New research by Valeria Molinero, distinguished professor of chemistry, and Atanu K. Metya, now at the Indian Institute of Technology Patna, shows how crystals of organic molecules, a common component of aerosols, can get the ...

Observations of groups of wild bonobos, reported in Scientific Reports, suggest that two infants may have been adopted by adult females belonging to different social groups. The findings may represent the first report of cross-group adoption in wild bonobos, and potentially also the first cases of cross-group adoption in wild apes. Bonobos form social groups of multiple males and females that sometimes temporarily associate with one another. Nahoko Tokuyama and colleagues observed four groups of wild bonobos between April 2019 and March 2020 in the Luo Scientific Reserve in Wamba, Democratic Republic of the Congo. The authors identified two infants whom ...

Newly excavated skeletal remains of an ankylosaurid -- a large armoured herbivore that lived during the Cretaceous Period -- may indicate that members of this family of dinosaurs were able to dig, according to a study published in Scientific Reports. The specimen, known as MPC-D 100/1359, may further our understanding of ankylosaurid behaviour during the Late Cretaceous (84-72 million years ago). Yuong-Nam Lee and colleagues excavated the skeletal elements of MPC-D 100/1359 from a deposit of the Baruungoyot Formation in the southern Gobi Desert, Mongolia, ...

UC Santa Cruz researchers published a new study--in collaboration with UC Water and the Sierra Nevada Research Institute at UC Merced--that suggests covering California's 6,350 km network of public water delivery canals with solar panels could be an economically feasible means of advancing both renewable energy and water conservation. The concept of "solar canals" has been gaining momentum around the world as climate change increases the risk of drought in many regions. Solar panels can shade canals to help prevent water loss through evaporation, and some types of solar panels also work better over canals, because the cooler environment keeps them from overheating. ...

Training neural networks to perform tasks, such as recognizing images or navigating self-driving cars, could one day require less computing power and hardware thanks to a new artificial neuron device developed by researchers at the University of California San Diego. The device can run neural network computations using 100 to 1000 times less energy and area than existing CMOS-based hardware. Researchers report their work in a paper published Mar. 18 in Nature Nanotechnology. Neural networks are a series of connected layers of artificial neurons, where the output of one layer provides the ...

From swallowing pills to injecting insulin, patients frequently administer their own medication. But they don't always get it right. Improper adherence to doctors' orders is commonplace, accounting for thousands of deaths and billions of dollars in medical costs annually. MIT researchers have developed a system to reduce those numbers for some types of medications. The new technology pairs wireless sensing with artificial intelligence to determine when a patient is using an insulin pen or inhaler, and flags potential errors in the patient's administration method. "Some past work reports that up to 70% of patients do not ...

A study by Monash University has uncovered that liver metabolism is disrupted in people with obesity-related type 2 diabetes, which contributes to high blood sugar and muscle loss - also known as skeletal muscle atrophy. Using human trials as well as mouse models, collaborative research led by Dr Adam Rose at Monash Biomedicine Discovery Institute has found the liver metabolism of the amino acid alanine is altered in people with obesity-related type 2 diabetes. By selectively silencing enzymes that break down alanine in liver cells, high blood sugar and muscle loss can be reversed by the restoration of skeletal muscle protein synthesis, a critical determinant of muscle size and strength. The research, published today in Nature Metabolism, has shown the altered liver metabolism ...

Scientists have witnessed bonobo apes adopting infants who were born outside of their social group for the first time in the wild. Researchers, including psychologists at Durham University, UK, twice saw the unusual occurrence among bonobos in the Democratic Republic of Congo, in central Africa. They say their findings give us greater insight into the parental instincts of one of humans' closest relatives and could help to explain the emotional reason behind why people readily adopt children who they have had no previous connection with. The research, led by Kyoto University, in Japan, is published in the journal Scientific Reports. Researchers observed a number of bonobo groups over several years in the Wamba area of ...

Researchers at Seattle's Institute for Systems Biology and their collaborators looked at the electronic health records of nearly 630,000 patients who were tested for SARS-CoV-2, and found stark disparities in COVID-19 outcomes -- odds of infection, hospitalization, and in-hospital mortality -- between White and non-White minority racial and ethnic groups. The work was published in the journal Clinical Infectious Diseases. The team looked at sociodemographic and clinical characteristics of patients who were part of the Providence healthcare system in Washington, Oregon and California. These ...

Metformin, a drug used to treat type-2 diabetes, could help reduce chronic inflammation in people living with HIV (PLWH) who are being treated with antiretroviral therapy (ART), according to researchers at the University of Montreal Hospital Research Centre (CRCHUM). Although ART has helped improved the health of PLWH, they are nevertheless at greater risk of developing complications related to chronic inflammation, such as cardiovascular disease. These health problems are mainly due to the persistence of HIV reservoirs in the patients' long-lived memory T cells and to the constant activation of their immune system. In a pilot study published recently in ...

MADISON, Wis. -- Scientists at the University of Wisconsin-Madison have developed a way to use a cell's own recycling machinery to destroy disease-causing proteins, a technology that could produce entirely new kinds of drugs. Some cancers, for instance, are associated with abnormal proteins or an excess of normally harmless proteins. By eliminating them, researchers believe they can treat the underlying cause of disease and restore a healthy balance in cells. The new technique builds on an earlier strategy by researchers and pharmaceutical companies to remove proteins residing inside of a cell, and expands on this system to include proteins ...

For the first time, scientists have documented biofluorescence in an Arctic fish species. The study, led by researchers at the American Museum of Natural History who spent hours in the icy waters off of Greenland where the red-and-green-glowing snailfish was found, is published today in the American Museum Novitates. "Overall, we found marine fluorescence to be quite rare in the Arctic, in both invertebrate and vertebrate lineages," said John Sparks, a curator in the American Museum of Natural History's Department of Ichthyology and one of the authors of the ...

The ongoing COVID-19 pandemic changed the higher education experience for students across the United States, with more than 90 percent of institutions reporting a shift in education delivery with the arrival of COVID-19. The rapid transition to remote study came with its own learning curve for students and faculty alike. But for many students with disabilities, the shift offered new educational modalities as well as challenges - and the hope that some changes will continue after the threat of the virus subsides. "This was a really unique, historical moment," says Nicholas Gelbar '06 (ED), '07 MEd, '13 Ph.D., an associate research professor with the Neag School of Education. "Remote learning, ...

Millions of children weighing less than 15kg are currently denied access to Ivermectin treatment due to insufficient safety data being available to support a change to the current label indication. The WorldWide Antimalarial Resistance Network (WWARN)'s new meta-analysis published today provides evidence that supports removing this barrier and improving treatment equity. ...

DURHAM, N.H.-- Researchers at the University of New Hampshire have found that more than 50% of children in high-risk populations in the United States are not receiving behavioral health services that could improve their developmental outcomes when it comes to mental and physical health problems. In their END ...

HOUSTON - (March 18, 2021) - If you're looking for one technique to maximize photon output from plasmons, stop. It takes two to wrangle. Rice University physicists came across a phenomenon that boosts the light from a nanoscale device more than 1,000 times greater than they anticipated. When looking at light coming from a plasmonic junction, a microscopic gap between two gold nanowires, there are conditions in which applying optical or electrical energy individually prompted only a modest amount of light emission. Applying both together, however, caused a burst of light that far exceeded ...

When it comes to recreational crabbing--one of the most iconic pastimes along Maryland's shores--the current estimate of 8% of "total male commercial harvest" runs just a little too low. Biologists, with local community support, found stronger evidence for the underestimate in the END ...