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Digital twin can protect physical systems and train new users

2021-04-07
It is more complicated than copy and paste, but digital twins could be way of future manufacturing according to researchers from the University of Kentucky. They developed a virtual environment based on human-robot interactions that can mirror the physical set up of a welder and their project. Called a digital twin, the prototype has implications for evolving manufacturing systems and training novice welders. They published their work in the IEEE/CAA Journal of Automatica Sinica (Volume 8, Issue 2, February 2021). "This human-robot interaction working style helps to enhance the human users' operational productivity and ...

The structure and function of cortical brain cells modulated by attention

The structure and function of cortical brain cells modulated by attention
2021-04-07
To effectively perform any daily task, the human brain needs to process information from the outside world using various cognitive functions. This cognitive processing passes through a dense interconnected network of cells whose physiology is specialized. The interconnected cell network needs to perform this processing of information efficiently and interact cooperatively to provide us, in real time, with useful instructions for living. Research published on 23 March in the journal Proceedings of the National Academy of Sciences of the United States of America challenges recent scientific advances seeking to find out how cognitive control and sensory information relate to the cortical machinery ...

First images of cells exposed to COVID-19 vaccine reveal native-like Coronavirus spikes

First images of cells exposed to COVID-19 vaccine reveal native-like Coronavirus spikes
2021-04-07
New research has for the first time compared images of the protein spikes that develop on the surface of cells exposed to the Oxford-AstraZeneca vaccine to the protein spike of the SARS-CoV-19 coronavirus. The images show that the spikes are highly similar to those of the virus and support the modified adenovirus used in the vaccine as a leading platform to combat COVID-19. The SARS-CoV-2 virus, which causes COVID-19, has a large number of spikes sticking out of its surface that it uses to attach to, and enter, cells in the human body. These spikes are coated in sugars, known as ...

'Patchwork' tumors prevalent across multiple cancer types

2021-04-07
Researchers at the Francis Crick Institute, as part of an international collaboration of scientists through the Pan-Cancer Analysis of Whole Genomes Consortium, have analysed the whole genomes of tumour samples from over 2,600 patients with different types of cancer. They identified a high prevalence of genetic diversity within individual tumours, which they further characterised. Their findings confirm that, even at late stages of development, tumour evolution is driven by changes that benefit the cancer. When cancer cells divide, errors occur in the process of copying their DNA. These copying errors mean that different tumours can be made up of cells presenting a wide range of genetic diversity. This variation is a challenge for doctors as a treatment that ...

The opportunities and risks of digitalization for sustainable development

2021-04-07
Digitalisation can support transitions towards a more sustainable society if technologies and processes are designed in line with suitable criteria. This requires a systemic focus on the risks and benefits of digital technologies across the three dimensions of sustainable development: the environment, society, and the economy. This is the conclusion of a study prepared by a team of researchers at the Institute for Advanced Sustainability Studies (IASS) in Potsdam. Applying this precautionary approach to digitalisation requires the active involvement of developers, users, and regulators. Digitalisation ...

Manual workers face twice the risk of developing ALS

Manual workers face twice the risk of developing ALS
2021-04-07
ALS is a progressive neurological disease that attacks the nerves that interact with the body's muscles. The disease typically leads to complete paralysis of the body, robbing patients of their ability to walk, speak, eat and breathe. Researchers studied ALS patients and healthy elderly volunteers living in Malta who took part in an ongoing study aiming at identifying genetic and environmental risk factors. Malta is a sovereign microstate in the middle of the Mediterranean Sea, and is home to a geographically and culturally isolated population. Recently, Maltese ALS patients were found to have a unique genetic makeup compared to ...

Foetus in bishop's coffin was probably his grandson

2021-04-07
Bishop Peder Winstrup died in 1679, and is one of the most well-preserved human bodies from the 1600s. Researchers at Lund University in Sweden may now have solved the mystery of why a foetus was hidden in his coffin in Lund Cathedral. DNA from the bishop and the foetus, along with kinship analyses, has shown that the child was probably the bishop's own grandson. Something is protruding between Bishop Peder Winstrup's two calves. The X-ray reveals small bones. Could it be an animal? When the image is studied more closely, the osteologists from Lund University can see faint signs of what is to become ...

Visionary bone damage study

Visionary bone damage study
2021-04-07
A novel way to pinpoint and illuminate bone damage promises to make X-rays more efficient at diagnosing bone and other injuries, Flinders University researchers say. The new technique, looking at potential biomedical applications of an ancient inorganic salt-based aggregation induced emission (AIE) radio-luminescence material, could open new frontiers in medicine including X-ray dosimetry, bioimaging and advanced applications such as optogenetics, says Professor Youhong Tang, from Flinders University's College of Science and Engineering. The review article, published by Professor Tang, postdoctoral student Dr Javad Tavokoli, colleagues in Hong Kong and Australian technology company Micro-X and, examined the potential of the AIEgen luminogens ...

Estimating costs of uterine transplantation

Estimating costs of uterine transplantation
2021-04-07
Sweden's acclaimed research on uterine transplants has taken a new step forward: into the field of health economics. Now, for the first time, there is a scientifically based estimate of how much implementing the treatment costs. The current research is based on the nine uterine transplants from living donors carried out in 2013, under the leadership of Mats Brännström, Professor of Obstetrics and Gynecology at Sahlgrenska Academy, University of Gothenburg, and Chief Physician at Sahlgrenska University Hospital. The transplants were performed within the scope of the world's first systematic, scientifically based study in the field. After ...

Training in compassion improves the well-being of relatives to people with mental illness

2021-04-07
If relatives of people with mental illness become better at accepting the difficult emotions and life events they experience - which is what training in compassion is about - their anxiety, depression and stress is reduced. These are the results of a new study from the Danish Center for Mindfulness at Aarhus University. Being a relative of a person with a mental illness can be very burdensome. It can feel like a great responsibility, and many people struggle with feelings of fear, guilt, shame and anger. A new study from the Danish Center for Mindfulness shows that eight weeks of training in compassion can significantly improve the well-being of relatives. Compassion is a human quality that is anchored in the recognition of and desire to relieve ...

Myositis-specific autoreactive T cells are pathogenic for dermatomyositis

2021-04-07
Tsukuba, Japan - Dermatomyositis is an idiopathic inflammatory myopathy that has been regarded as an autoimmunity-based disorder, although its pathogenesis remains unclear. In this study, researchers from the University of Tsukuba used a mouse model to identify a mechanism by which dermatomyositis may develop in humans. The animal model and findings can be used to better understand the disease and develop disease-specific treatments. Dermatomyositis belongs to a group of idiopathic inflammatory myopathies that are associated with the presence of specific autoantibodies in patient sera. Multiple myositis-specific autoantibodies, which target proteins ubiquitously expressed in the nucleus or cytoplasm, have been described. One ...

Scientists develop eco-friendly pollen sponge to tackle water contaminants

2021-04-07
A team of scientists led by Nanyang Technological University, Singapore (NTU Singapore) has created a reusable, biodegradable sponge that can readily soak up oil and other organic solvents from contaminated water sources, making it a promising alternative for tackling marine oil spills. Made of sunflower pollen, the sponge is hydrophobic - it repels water - thanks to a coat of natural fatty acid on the sponge. In lab experiments, the scientists showed the sponge's ability to absorb oil contaminants of various densities, such as gasoline and motor oil, ...

Black hole pairs found in distant merging galaxies

2021-04-07
Astronomers have found two close pairs of quasars in the distant Universe. Follow-up observations with Gemini North spectroscopically resolved one of the distant quasar pairs, after their discovery with the Hubble Space Telescope and Gaia spacecraft. These quasars are closer together than any pair of quasars found so far away, providing strong evidence for the existence of supermassive black hole pairs as well as crucial insight into galaxy mergers in the early Universe. The quasars in each of the two pairs are separated by just over 10,000 light-years, suggesting ...

A few hundred dollars makes a difference in use of long-lasting birth control

A few hundred dollars makes a difference in use of long-lasting birth control
2021-04-07
Getting a birth control implant used to cost some women hundreds of dollars, if they were among the nearly half of privately insured Americans covered by a health plan with a high deductible that they were responsible for paying. But a new study in the April issue of Health Affairs shows that after the Affordable Care Act's no-cost birth control provision took effect in 2013, women in these high-deductible health plans (HDHPs) opted for long-acting contraception even more than women with other types of health plans. The study's findings have important policy implications, because employers now have the ability to opt out of the birth control portion of the ACA, following a Supreme Court case decided in 2020. Many employers have shifted to HDHPs to hold down their overall health ...

Wild barley from Jordan holds key to stem rust resistance

Wild barley from Jordan holds key to stem rust resistance
2021-04-07
Stem rust is a devastating disease of cereal crops, including barley, one of the first domesticated crops in agriculture and the fourth most widely grown crop in the world. Barley is unique because it is one of only a few crops that can be cultivated in almost any climate and across a range of elevations, making it economically and nutritionally important. Stem rust is one of the biggest threats to barley production and capable of causing complete crop loss during severe epidemics. And since barley is also used as malt for beer and spirits and feed for animals ...

Is combat-induced post-traumatic stress disorder unique to industrialized warfare?

Is combat-induced post-traumatic stress disorder unique to industrialized warfare?
2021-04-07
Thirty years ago, clinical psychiatrist Jonathan Shay drew attention to similarities between the trauma experienced by the Greek warriors, as documented in the epic poem "The Iliad," and Vietnam veterans in America. Could the experience of war impact people in similar ways in vastly different cultural milieus? Research published this week by ASU researcher Sarah Mathew and former ASU postdoctoral researcher Matthew Zefferman in the Proceedings of the National Academy of Sciences shows that Turkana pastoralist warriors from Kenya also experience PTSD (post-traumatic stress disorder) symptoms, even though their lifestyles and combat experiences are ...

Aquatic ecosystems source of half of global methane emissions

2021-04-07
Direct human alterations to natural aquatic ecosystems can increase methane emissions, a new study has found. Atmospheric methane has tripled since pre-industrial times. It traps heat far more effectively than carbon dioxide and accounts for 25% of atmospheric warming to date. And much of that methane is coming from aquatic ecosystems, with human activities contributing to the emissions levels, a new paper published in Nature Geoscience has found. The global contribution and importance of aquatic ecosystems as methane emitters has been underestimated, ...

How the spinifex got its hole

2021-04-07
Anyone who has visited the Australian outback would be familiar with spinifex grasses, which cover almost a fifth of our continent. Like many scientists, they may have also wondered why this iconic arid grass grows in striking ring shapes. Previous studies have tested whether spinifex rings could be caused by termites, water availability or nutrient depletion, but none has provided a convincing explanation. Now scientists from UNSW Sydney have found that pathogenic soil microbes play a role in how the spinifex got its hole. Their study, the first of its kind in an arid ecosystem, has been published in the Australian Journal of Botany. Professor Angela Moles and Neil Ross from ...

Stem cell therapy research could help patients with non-healing diabetic foot ulcers

Stem cell therapy research could help patients with non-healing diabetic foot ulcers
2021-04-07
Durham, NC - According to the results of a phase 1 clinical trial just published in STEM CELLS Translational Medicine, a new stem cell therapy shows promise of making diabetes-related amputations a thing of the past. The trial involved injecting diabetes patients suffering from non-healing diabetic foot ulcers (DFU) with a cell preparation containing adult stem cells harvested from their own fat. The results showed that the treatment induced regeneration of the blood vessels surrounding the DFUs, accelerated healing - all with no serious side effects. "Non-healing diabetic foot ulcers usually ...

Eucalyptus trees can be genetically modified not to invade native ecosystems

Eucalyptus trees can be genetically modified not to invade native ecosystems
2021-04-07
CORVALLIS, Ore. - Eucalyptus, a pest-resistant evergreen valued for its hardy lumber and wellness-promoting oil, can be genetically modified not to reproduce sexually, a key step toward preventing the global tree plantation staple from invading native ecosystems. Oregon State University's Steve Strauss led an international collaboration that showed the CRISPR Cas9 gene editing technique could be used with nearly 100% efficiency to knock out LEAFY, the master gene behind flower formation. "The flowers never developed to the point where ovules, pollen or ...

Silver linings to New Zealand lockdown

Silver linings to New Zealand lockdown
2021-04-07
Two thirds of New Zealanders believed there were 'silver linings' to the country's Alert Level 4 COVID-19 lockdown imposed in March last year, a University of Otago survey has found. The researchers were able to question New Zealanders while they were at home, giving a unique insight into their lives during the nationwide lockdown between 25 March and 23 April, widely regarded as one of the strictest imposed anywhere in the world. One year on from lockdown, the results of their study have been published in the international scientific journal, PLOS ONE. Participants were asked 'Have you experienced any silver linings, or positive aspects during the COVID-19 Level 4 lockdown' and were able to answer 'yes, for me personally', ...

Nanoparticles reveal their location via mirror SELFI

Nanoparticles reveal their location via mirror SELFI
2021-04-07
Can a mirror turn an orange into a doughnut? The answer is definitely no in the real (macro) world. But at the nanoscale, a mirror can turn an "orange" shaped pattern into a "doughnut" shaped pattern by overlapping the "orange" with its reflected mirror image. A team of researchers from the University of Technology Sydney (UTS) has shown for the first time that fluorescent nanoparticles placed near a mirror generate unique patterns that can be used to pinpoint their location. The researchers attribute this effect to the light emitting nanoparticle's interference with its own mirror image. Using this method they can also detect the size of particles to a resolution of one nanometre - or around 1/80,000th of the diameter of a human ...

Misogynistic tweets correlate with violence against women

Misogynistic tweets correlate with violence against women
2021-04-07
Areas with a relatively greater amount of misogynistic tweets have higher incidences of domestic and family violence, a UNSW study has found. The study, published in Psychological Science, not only found this connection with domestic and family violence carried over from one year to the next, but also occurred despite the 'usual suspects' of domestic violence, such as alcohol and inequality. Examples of misogynistic tweets identified by the researchers included, "Women are all bitches," "Whore had it coming," and, "Make me a sandwich, slut." "We found that misogynistic ...

New proposal for the management of low back pain with a proprioceptive approach

New proposal for the management of low back pain with a proprioceptive approach
2021-04-07
Ever since the early humans learned to walk upright, they have suffered, as an unfortunate consequence of their erect posture, from low back pain. Modern understanding on this matter dictates that low back pain, in particular, is caused due to a postural instability resulting from poor "proprioception", which is a term for the perception of part of our body's own position in space. In fact, our trunk and lower legs are key to maintaining postural stability due to the presence of "proprioceptors"--sensory receptors responding to position and movement--in those areas. Elderly people suffering from low back pain tend to have poorly performing proprioceptors, ...

Scientists harness chaos to protect devices from hackers

2021-04-07
COLUMBUS, Ohio - Researchers have found a way to use chaos to help develop digital fingerprints for electronic devices that may be unique enough to foil even the most sophisticated hackers. Just how unique are these fingerprints? The researchers believe it would take longer than the lifetime of the universe to test for every possible combination available. "In our system, chaos is very, very good," said Daniel Gauthier, senior author of the study and professor of physics at The Ohio State University. The study was recently published online in the journal IEEE Access. The researchers created a new version ...
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