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With impressive accuracy, dogs can sniff out coronavirus

With impressive accuracy, dogs can sniff out coronavirus
2021-04-15
Many long for a return to a post-pandemic "normal," which, for some, may entail concerts, travel, and large gatherings. But how to keep safe amid these potential public health risks? One possibility, according to a new study, is dogs. A proof-of-concept investigation published today in the journal PLOS ONE suggests that specially trained detection dogs can sniff out COVID-19-positive samples with 96% accuracy. "This is not a simple thing we're asking the dogs to do," says Cynthia Otto, senior author on the work and director of the University of Pennsylvania School of Veterinary Medicine Working Dog Center. "Dogs have to ...

Novak Djokovic now has a tiny new snail species named after him

Novak Djokovic now has a tiny new snail species named after him
2021-04-15
Do freshwater snails make good tennis players? One of them certainly has the name for it. Enter Travunijana djokovici, a new species of aquatic snail named after famous Serbian ten­nis player Novak Djokovic. Slovak biospeleologist Jozef Grego and Montenegrin zoologist Vladimir Pesic of the University of Montenegro discovered the new snail in a karstic spring near Podgorica, the capital of Montenegro, during a field trip in April 2019. Their scientific article, published in the open-access, peer-reviewed journal Subterranean Biology, says they named it after Djokovic "to acknowledge his inspiring enthusiasm and energy." "To discover some of the world's rarest animals that inhabit the unique underground habitats of the Dinaric karst, to reach inaccessible cave and spring habitats ...

Norovirus clusters are resistant to environmental stresses and UV disinfection, new study finds

Norovirus clusters are resistant to environmental stresses and UV disinfection, new study finds
2021-04-15
WASHINGTON (April 15, 2021) -- Clusters of a virus known to cause stomach flu are resistant to detergent and ultraviolet disinfection, according to new research co-led by END ...

German National HPC Centre provides resources to look for cracks in the standard model

German National HPC Centre provides resources to look for cracks in the standard model
2021-04-15
Since the 1970s, the Standard Model of Physics has served as the basis from which particle physics are investigated. Both experimentalists and theoretical physicists have tested the Standard Model's accuracy, and it has remained the law of the land when it comes to understanding how the subatomic world behaves. This week, cracks formed in that foundational set of assumptions. Researchers of the "Muon g-2" collaboration from the Fermi National Accelerator Laboratory (FNAL) in the United States published further experimental findings that show that muons--heavy subatomic relatives of electrons--may have a larger "magnetic moment" than earlier Standard Model estimates had predicted, indicating that an unknown particle or force might be influencing ...

The architect of genome folding

The architect of genome folding
2021-04-15
The DNA molecule is not naked in the nucleus. Instead, it is folded in a very organized way by the help of different proteins to establish a unique spatial organization of the genetic information. This 3D spatial genome organization is fundamental for the regulation of our genes and has to be established de novo by each individual during early embryogenesis. Researchers at the MPI of Immunobiology and Epigenetics in Freiburg in collaboration with colleagues from the Friedrich Mischer Institute in Basel now reveal a yet unknown and critical role of the protein HP1a in the 3D genome re-organization after fertilisation. The study published in the scientific journal Nature identifies HP1a as an epigenetic regulator that is involved in establishing ...

Potential impact of pass/fail USMLE Step 1 scoring on radiology residency applications

Potential impact of pass/fail USMLE Step 1 scoring on radiology residency applications
2021-04-15
Leesburg, VA, April 15, 2021--A Scientific E-Poster to be presented at the 2021 ARRS Virtual Annual Meeting found that as the United States Medical Licensing Examination (USMLE) Step 1 transitions from a numerical score to pass or fail--as early as January 2022--radiology residency program directors will likely rely on USMLE Step 2 Clinical Knowledge (CK) scores as an objective and standardized metric to screen applicants. "However," wrote lead investigator Rebecca Zhang of the University of Maryland School of Medicine in Baltimore, "program directors remain unsure whether they will ...

Outcome predictive performance of admission chest radiographs in COVID-19 patients

Outcome predictive performance of admission chest radiographs in COVID-19 patients
2021-04-15
Leesburg, VA, April 15, 2021--A Scientific E-Poster to be presented at the 2021 ARRS Virtual Annual Meeting found that in the setting of a high pretest probability of COVID-19 infection or with a quick turnaround of the rapid real-time reverse transcriptase-polymerase chain reaction (RT-PCR) COVID-19 test, a chest x-ray (CXR) scoring system may be used prospectively to predict patient outcomes. "We developed an accurate and reliable tool for classifying COVID-19 severity, which can be used both at the attending chest radiologist and junior resident level. This study identifies the laboratory, clinical and radiographic data that predict important patient outcomes such as death, intubation, and the need for chronic renal replacement ...

TPU scientists find method to more effectively predict properties of ClO2 isotopologues

2021-04-15
Scientists of Tomsk Polytechnic University has conducted research on the 35ClO2 isotope and developed a mathematical model and software, which allow predicting characteristics by 10 folds more accurate than already known results. The research work was conducted by a research team of Russian, German and Swiss scientists. The research findings are published in the Physical Chemistry Chemical Physics (IF: 3,4; Q1) academic journal and listed as one of the best articles. The ClO2 molecule is extremely important for medicine and biophysics, as well as for the Earth atmosphere. It is used in medicine for disinfection and ...

How changing income assistance payment schedules impact drug use and related harm

2021-04-15
A study published this week in The Lancet Public Health examines how we can use our income assistance systems to address drug use and drug-related harm. The study, led by University of British Columbia (UBC) medical sociologist Dr. Lindsey Richardson and conducted at the British Columbia Centre on Substance Use (BCCSU), tests whether varying the timing and frequency of income assistance payments can mitigate drug-related harms linked to the existing once-monthly payment schedule that is common across North America and Europe. Monthly synchronized income assistance payments have long been linked to considerable and costly increases in drug use and resulting harm, including overdose, hospital admission, treatment interruption and emergency service calls. The study finds that varying when ...

HIV has been had

HIV has been had
2021-04-15
Tokyo, Japan - A team of scientists led by the Institute of Biomaterials and Bioengineering at Tokyo Medical and Dental University (TMDU) have created novel molecules that prevent human immunodeficiency virus (HIV) particles from attacking immune cells. This is accomplished by injecting compounds mimicking the protein the virus usually uses to enter the cells. This work may lead to new treatments for HIV that may be more effective at stopping the proliferation of the virus with fewer side effects. HIV is a very dangerous pathogen because it attacks the very immune cells, including T helper cells, that are needed for the body to fight back. An HIV particle first ...

New benefits from anti-diabetic drug metformin

New benefits from anti-diabetic drug metformin
2021-04-15
Researchers from Kumamoto University (Japan) have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating pathological conditions like reduced kidney function, glomerular damage, inflammation and fibrosis. Metformin's mechanism is different from existing therapeutics which only treat symptoms, such as the blood pressure drug losartan, so the researchers believe that a combination of these medications at low dose will be highly beneficial. CKD (chronic kidney disease) ...

Uncovering the secrets of some of the world's first color photographs

2021-04-15
It is often said that before air travel our skies were bluer yet how, in the 21st century, could we ever know what light and colors were like one hundred years ago? Recently, a group of researchers from EPFL's Audiovisual Communications Laboratory, in the School of Computer and Communication Sciences (IC), had a unique opportunity to try to find out. Normally hidden treasures locked away in the vaults of a handful of museums, the researchers were offered access to some of the original photographic plates and images of the scientist and inventor Gabriel Lippmann, who won the 1908 Nobel Prize in physics for his method of reproducing colors in photography. In a paper just published in the Proceedings of the National ...

Recent wildlife documentaries affect public understanding of wider conservation

2021-04-15
Research led by the University of Kent's Durrell Institute of Conservation and Ecology (DICE) has found that the personification of animals in recent wildlife documentaries leads to significant misinformation and creates problems for public understanding of wider conservation. In a research paper published by People and Nature, Professor Keith Somerville (DICE), Dr Amy Dickman, Dr Paul Johnson (both from the Wildlife Conservation Research Unit, University of Oxford), and Professor Adam Hart (University of Gloucestershire) argue that the portrayal of charismatic animals in nature films, while ...

Objective analysis of stress in the classroom

2021-04-15
"This enables us to contrast the subjective perception of stress with an objective measurement method and compare the two," explains Nina Minkley. Contrary to expectations, it turned out that the effort invested in the task does not increase with its difficulty, nor does the stress level. The study was featured in the journal Frontiers in Education on 12. April 2021. Simple questionnaire surveys criticised To date, the stress experience of students has mostly been surveyed with questionnaires. But this approach has been criticised, because many factors have an effect on one's own perception that have nothing to do with the task. "For example, women often report higher stress levels ...

Researchers identify five double star systems potentially suitable for life

2021-04-15
Almost half a century ago the creators of Star Wars imagined a life-sustaining planet, Tatooine, orbiting a pair of stars. Now, 44 years later, scientists have found new evidence that that five known systems with multiple stars, Kepler-34, -35, -38, -64 and -413, are possible candidates for supporting life. A newly developed mathematical framework allowed researchers at New York University Abu Dhabi and the University of Washington to show that those systems -- between 2764 and 5933 light years from Earth, in the constellations Lyra and Cygnus -- support a permanent "Habitable Zone", a region around stars in which liquid water could ...

3500 year-old honeypot: Oldest direct evidence for honey collecting in Africa

3500 year-old honeypot: Oldest direct evidence for honey collecting in Africa
2021-04-15
Honey is humankind's oldest sweetener - and for thousands of years it was also the only one. Indirect clues about the significance of bees and bee products are provided by prehistoric petroglyphs on various continents, created between 8,000 and 40,000 years ago. Ancient Egyptian reliefs indicate the practice of beekeeping as early as 2600 year BCE. But for sub-Saharan Africa, direct archaeological evidence has been lacking until now. The analysis of the chemical residues of food in potsherds has fundamentally altered the picture. Archaeologists at Goethe University in cooperation with chemists at the University ...

First 3D-printed proton-conductive membrane paves way for tailored energy storage devices

First 3D-printed proton-conductive membrane paves way for tailored energy storage devices
2021-04-15
The advent and increased availability of 3D printing is leading to more customizable parts at lower costs across a spectrum of applications, from wearable smart devices to autonomous vehicles. Now, a research team based at Tohoku University has 3D printed the first proton exchange membrane, a critical component of batteries, electrochemical capacitors and fuel cells. The achievement also brings the possibility of custom solid-state energy devices closer to reality, according to the researchers. The results were published on March 29 in ACS Applied Energy Materials, a journal of the American Chemical Society. "Energy storage devices whose shapes can be tailored enable entirely new possibilities for applications related, for example, to smart wearable, electronic medical ...

Classification scheme developed for newly identified multiple sclerosis-like disease

Classification scheme developed for newly identified multiple sclerosis-like disease
2021-04-15
Researchers in the Department of Neurology at Tohoku University, which is led by professor Masashi Aoki, have developed a classification scheme for neuromyelitis optica spectrum disorder, a rare autoimmune disease that until recently was thought to be a type of multiple sclerosis (MS). The new taxonomy for the disease replaces one borrowed from MS but which was inappropriate for what is in fact a distinct condition. An autoimmune disease, neuromyelitis optica spectrum disorder (NMOSD), was for a long time thought to be a type of multiple sclerosis (MS), but it has recently been identified as an entirely different illness. As a result of this confusion, ...

McMaster scientists discover trained immune cells are highly effective against cancer

McMaster scientists discover trained immune cells are highly effective against cancer
2021-04-15
Hamilton, ON (April 14, 2021) - Modified immune cells that ruthlessly kill cancerous tumours may prove a game-changer for people living with late-stage cancer. McMaster University researchers Ali Ashkar and Sophie Poznanski have uncovered that changing the metabolism of natural killer (NK) immune cells allows these cells to overcome the hostile conditions found inside tumours and destroy advanced ovarian and lung cancer. In the past decade cancer immunotherapy has achieved tremendous therapeutic effects in patient with blood cancers. However, the immunosuppressive conditions found inside solid tumours, whose aggressive growth starves surrounding healthy tissues of energy, have ...

Two distinct types of COVID-19-associated acute respiratory distress syndrome identified

2021-04-15
BOSTON - Approximately one in four patients hospitalized for the acute respiratory distress syndrome (ARDS) associated with severe COVID-19 infections may have a distinct phenotype (disease presentation) or biochemical profile associated with organ dysfunction, blood-clotting abnormalities and greater risk of death than patients with other, seemingly similar forms of the disease, researchers at Massachusetts General Hospital (MGH) have found. Among 263 patients admitted to intensive care units (ICUs) at MGH for respiratory failure due to severe COVID-19 infection, 70 (26.6%) had increased ...

Snake species from different terrains surrender surface secrets behind slithering success

2021-04-15
WASHINGTON, April 15, 2021 -- Some snake species slither across the ground, while others climb trees, dive through sand or glide across water. Today, scientists report that the surface chemistry of snake scales varies among species that negotiate these different terrains. The findings could have implications for designing durable materials, as well as robots that mimic snake locomotion to cross surfaces that would otherwise be impassable. The researchers will present their results today at the spring meeting of the American Chemical Society (ACS). ACS Spring 2021 is being held online April 5-30. Live sessions will be hosted April 5-16, and on-demand and networking ...

Good dental health may help prevent heart infection from mouth bacteria

2021-04-15
DALLAS, April 15, 2021 - Maintenance of good oral health is more important than use of antibiotics in dental procedures for some heart patients to prevent a heart infection caused by bacteria around the teeth, according to a new American Heart Association (AHA) scientific statement published today in the association's flagship journal, Circulation. Infective endocarditis (IE), also called bacterial endocarditis, is a heart infection caused by bacteria that enter the bloodstream and settle in the heart lining, a heart valve or a blood vessel. It is uncommon, ...

UZH researchers find new measure to predict stress resilience

2021-04-15
Researchers at the University of Zurich show that increased sensitivity in a specific region of the brain contributes to the development of anxiety and depression in response to real-life stress. Their study establishes an objective neurobiological measure for stress resilience in humans. Some people don't seem to be too bothered when it comes to handling stress. For others, however, prolonged exposure to stress can lead to symptoms of anxiety and depression. While stress resilience is a widely discussed concept, it is still very challenging to predict people's ...

With the right carbon price path there is no need for excessive CO2 removal

2021-04-15
Technologies to remove CO2 from the atmosphere, such as reforestation or bioenergy with carbon capture and storage (BECCS), are an indispensable part in most scenarios to limit climate change. However, excessive deployment of such technologies would carry risks such as land conflicts or enhanced water scarcity due to a high demand for bioenergy crops. To tackle this trade-off, a team of researchers from Potsdam and Berlin has now identified requirements for a dynamic, long-term carbon price pathway to reduce the demand for CO2 removal technologies and thus effectively limit long-term ...

Pregnancy increases kidney stone risk, Mayo Clinic study finds

2021-04-15
ROCHESTER, Minn. - Though researchers have long known that several physiological and anatomical changes occur during pregnancy that can contribute to kidney stone formation, evidence of the link has been lacking. But now Mayo Clinic researchers believe they have that evidence. An observational study that reviewed the medical records for nearly 3,000 female patients from 1984 to 2012 finds that pregnancy increases the risk of a first-time symptomatic kidney stone. The risk peaks close to delivery and then improves by one year after delivery, though a modest risk of developing kidney stones continues beyond ...
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